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Name : Tcur_2040 (Tcur_2040) Accession : YP_003299645.1 Strain : Thermomonospora curvata DSM 43183 Genome accession: NC_013510 Putative virulence/resistance : Resistance Product : beta-lactamase Function : - COG functional category : V : Defense mechanisms COG ID : COG2602 EC number : 3.5.2.6 Position : 2401262 - 2402164 bp Length : 903 bp Strand : + Note : PFAM: penicillin-binding protein transpeptidase; KEGG: pla:Plav_3016 beta-lactamase DNA sequence : ATGCCACCTCACCGTCCCGCACCGGCCCCCCGGCGTCCGCGGACCGGGCGGCTCGCCGCCGTCCTCACCGCGCTGACGCT CCTCGGCGCCGCCTGCGCGGCCCCCGCCACCCCGCCGCGGGCCGCGCAGAGCACCACCGCGACCGCGCCGCACAGCCGGC CGGCGTCCCCGCAGGTCCGCGACGATCTGCTGGAGGTCTTCCGCCAGGCCTCCGTCACCGGAACGTTCGTGCTGATGGAG GCGGAAAGCGGCCGCACCACCGTGGTCGGCCGCGAACGTGCCGCCCGCCGCTACGTGCCCGCCTCCACCTTCAAGATCCC CCACAGCCTGATCGCCCTGGAGACGGGCGCGGTCGCAGACGCCGAGGAGGTGATCCCCTACGGGGGACGGCCCCAGCCCC GTCCCGAATGGGAACGGGACATGACCTTGCGCGAGGCGATCGCGGCCTCCAACGTGCCGGTGTTCCAAACCCTGGCCCGC CGGATCGGCCTGGCACGGGAACGGCACTGGCTGCGGCGGCTCGGCTACGGCAACCGGCAGACCGGCACGGCGCTCGACCG CTTCTGGCTGGACGGGCCGCTGGCGATCTCGGCGCTCGAACAGACCGGCTTCCTGGCGCGCCTGGCCACCGGGCGGCTGC CGGCCTCCCGCCGCCACCAGCGCCTCGTCCGCGACCTGCTGCGCGTCGAACGCACCGTGGACTACGCGTTGTTCGCCAAG ACCGGCTGGGGCACGGCCGGCGACCCCGGCATCGGCTGGTGGGTCGGCTGGGTCGAACGCGACGGCCGGATCTGGACCTT CGCCCTCAACATCGACGTCGGCGACGACCGCGACGCCGCCCTGCGGATCCCGCTGGGACGGAGACTGCTGCACCGCCTGG GCGTGCTGCCGTACCCCGCCTAG Protein sequence : MPPHRPAPAPRRPRTGRLAAVLTALTLLGAACAAPATPPRAAQSTTATAPHSRPASPQVRDDLLEVFRQASVTGTFVLME AESGRTTVVGRERAARRYVPASTFKIPHSLIALETGAVADAEEVIPYGGRPQPRPEWERDMTLREAIAASNVPVFQTLAR RIGLARERHWLRRLGYGNRQTGTALDRFWLDGPLAISALEQTGFLARLATGRLPASRRHQRLVRDLLRVERTVDYALFAK TGWGTAGDPGIGWWVGWVERDGRIWTFALNIDVGDDRDAALRIPLGRRLLHRLGVLPYPA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| blaOXA-129 | AET25386.1 | OXA-129 beta-lactamase | Not tested | PAGI-2(C) | Protein | 2e-44 | 46 |
| bla OXA-129 | AFG30109.1 | OXA-129 beta-lactamase | Not tested | PAGI-2 | Protein | 2e-44 | 46 |
| ACICU_00226 | YP_001844885.1 | Beta-lactamase class D | Not tested | AbaR20 | Protein | 1e-29 | 43 |
| bla OXA-10 | CAJ77047.1 | Oxacillinase | Not tested | AbaR1 | Protein | 2e-45 | 42 |
| blaOXA-2 | YP_005176242.1 | beta-lactamase OXA-2 protein | Not tested | ICEPmu1 | Protein | 4e-29 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AM932669.1.gene2.p01 | Protein | 1e-44 | 46 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | X58272.1.gene1.p01 | Protein | 4e-44 | 44 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AY423074.1.gene1.p01 | Protein | 6e-37 | 44 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AF024602.1.gene3.p01 | Protein | 5e-30 | 43 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AY343493.1.gene1.p01 | Protein | 2e-34 | 43 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | U37105.2.gene2.p01 | Protein | 1e-45 | 42 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | NC_010410.6002874.p0 | Protein | 1e-45 | 42 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | EU086834.1.gene1.p01 | Protein | 5e-39 | 42 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | JF273470.1.gene1.p01 | Protein | 3e-39 | 42 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | EU086830.1.gene1.p01 | Protein | 5e-39 | 42 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AF300985.1.gene1.p01 | Protein | 5e-29 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | GU831575.1.gene1.p01 | Protein | 1e-39 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | DQ519090.1.gene1.p01 | Protein | 2e-39 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | NC_010481.6155789.p0 | Protein | 1e-39 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | EF102240.1.gene13.p0 | Protein | 2e-39 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AY665723.gene.p01 | Protein | 1e-39 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | HM570036.1.gene1.p01 | Protein | 2e-35 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AF371964.1.gene1.p1 | Protein | 1e-29 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AY139598.1.gene3.p01 | Protein | 6e-29 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AM412777.1.gene1.p01 | Protein | 3e-45 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | U59183.1.gene3.p01 | Protein | 5e-45 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AY445080.1.gene1.p01 | Protein | 2e-45 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AF231133.1.gene3.p01 | Protein | 1e-43 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | AJ854182.1.gene1.p01 | Protein | 3e-45 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | Z22590.1.gene1.p01 | Protein | 4e-45 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | M95287.gene.p01 | Protein | 2e-29 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | U63835.1.gene1.p01 | Protein | 4e-29 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | L07945.1.gene1.p01 | Protein | 1e-29 | 41 |
| Tcur_2040 | YP_003299645.1 | beta-lactamase | JF795487.1.gene1.p01 | Protein | 2e-28 | 41 |
