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Name : Tcur_1050 (Tcur_1050) Accession : YP_003298674.1 Strain : Thermomonospora curvata DSM 43183 Genome accession: NC_013510 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 1199172 - 1200323 bp Length : 1152 bp Strand : + Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: scl:sce6169 cystathionine gamma-synthase DNA sequence : ATGGACGAGGACGTTCAACGGGGCTTTGAGACGCTGGCCATCCATGCCGGGCAGGAGCCCGACCCGACGACCGGCGCGGT GGTCCCGCCGATATATCAGGTGTCCACCTACAAACAGGACGGGGTGGGCGGGCTGCGCGGCGGCTACGAGTACAGCCGCT CGGCCAACCCGACCCGCACGGCGCTGGAGGAGTGCCTGGCGGCGCTGGAGGGCGGGGTGCGCGCCCTGGCGTTCGCCTCC GGCCTGGCCGCCGAGGACACCCTGCTGCGCACCATCTGCGCGCCCGGGGACCACATCATCGCCCCCAACGACGCCTACGG CGGCACCTACCGGCTGTTCTCCAAGGTCTACGAGCGGTGGGGCGTGACCTGCGACCCGGTGCCGCTGGGGGATCTGGAGG CGGTGCGGGCGGCCGTCCGCGAGGGGGTCACCAAGGCGATCTGGGTGGAGACCCCGACCAACCCGCTGCTGGGCATCGCC GATATCGCGGCGCTGGCGGCCATCGCGGTCGAGGCCGGGGCGCTGCTGGTGGTCGACAACACCTTCGCCTCCCCCTACCT GCAGCAGCCGCTGACGCTGGGCGCCCACGTGGTGGTGCACTCCACCACCAAGTACCTGGGCGGGCACTCCGACGTGGTCG GCGGGGCGCTGGTGACCTCCGACGCCGAACTGGGGGAGCGGCTGGCCTTCCACCAGAACGCCATGGGCGCCATCGCCGGG CCGTTCGACTCGTGGCTGACGCTGCGCGGCATCAAGACGCTGGGCGTGCGGATGGACCGGCACTGCGCCAACGCCGCGGC GGTGGTGAAGCTGCTCACCGAGCACCCGGCGGTACGGCAGGTGCTCTACCCGGGACTGCCCGACCACCCCGGGCACGACA TCGCCGTCAAGCAGATGCGGGCCTTCGGCGGGATGGTCTCGTTCCGGATGGACTCCCCGGAGGCGGCGCTGCGGGTGTGC GAGCGCACCAAGGTGTTCACCCTCGGCGAGTCGCTGGGCGGCGTGGAGTCCCTCATCGAGCATCCGGCGAAGATGACGCA CGCCTCGGCGGCCGGTTCCCCGCTGGAGGTCCCCGCCGACCTGGTGCGCCTGTCGGTGGGCATCGAGAGCGTCGAGGATC TGCTGGCCGATCTGAGACAGGCTCTAGGGTGA Protein sequence : MDEDVQRGFETLAIHAGQEPDPTTGAVVPPIYQVSTYKQDGVGGLRGGYEYSRSANPTRTALEECLAALEGGVRALAFAS GLAAEDTLLRTICAPGDHIIAPNDAYGGTYRLFSKVYERWGVTCDPVPLGDLEAVRAAVREGVTKAIWVETPTNPLLGIA DIAALAAIAVEAGALLVVDNTFASPYLQQPLTLGAHVVVHSTTKYLGGHSDVVGGALVTSDAELGERLAFHQNAMGAIAG PFDSWLTLRGIKTLGVRMDRHCANAAAVVKLLTEHPAVRQVLYPGLPDHPGHDIAVKQMRAFGGMVSFRMDSPEAALRVC ERTKVFTLGESLGGVESLIEHPAKMTHASAAGSPLEVPADLVRLSVGIESVEDLLADLRQALG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 7e-75 | 50 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 7e-76 | 50 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 2e-52 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Tcur_1050 | YP_003298674.1 | cystathionine gamma-synthase | BAC0207 | Protein | 1e-55 | 44 |
