Gene Information

Name : Rmar_1667 (Rmar_1667)
Accession : YP_003290941.1
Strain : Rhodothermus marinus DSM 4252
Genome accession: NC_013501
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1931702 - 1932862 bp
Length : 1161 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: afw:Anae109_3196 cystathionine gamma-synthase

DNA sequence :
ATGCAGCCACAGACGCGTCTGACGCTGGCCGGTCAGCAGACCGATTCCAGCTACAACAGCATCGTCCCGCCCATTTACCA
GTGCGCCACGTTCCGCTTCGAGGATGTCGGGTTGACGAAGGGATACGACTATTCGCGCAGCGGCAACCCGACGCGGCGTG
CGCTGGAAGAGGTGCTGGCCGACCTGGAGGGCGGCGCCGACGCCGTGGCCACCACCAGCGGCATGGCGGCCGTTTCGACG
GTGCTGGCCCTGTTCGACCACGGCATCCATGTGATCTGTGCCCACGACTGCTACGGCGGCACCGAGCGGCTGCTGAGCCT
GCTGGCGCGACAGGGCAAGCTGGAGGTGTCGTTCGTCGACCTGCGCGACCTGCAGGCCGTCGAGGCGGCCATCCGCCCGA
ACACCCGGCTCATCTGGGTGGAAACGCCCTCCAACCCGCTGCTGCGCATCGTCGATCTGGATGCACTCTGTCGCTTCGCG
AAAGCCCACGACCTGCTGGTGGTGGTGGACAATACCTTCCTGTCGCCGCTGCAGCAGCGGCCCATGGACTTCGGCGCCGA
CATCGTCGTCTATTCGACCACGAAGTACCTGAACGGCCACTCCGACGTCATCGGCGGGGCGGTCATCGTCCGCACCGGGG
AATTGAACGAGCAGTTGCAGTTTGTGGCGAACGCCCACGGCACCATCGCCGGTCCCTTCGACTGCTGGCTCGTACTGCGC
GGGCTGAAGACGCTTCCGGTGCGCATTCGCCAGCATGAGCACAACGCCATGGCCGTGGCGCGCTTCCTGGCGCAGCATCC
CAACGTCGAGCGCGTGTTCTATCCCGGATTGCCCTCGCATGAAGGCCACGAGATCGCGGCGCGCCAGCAGAAAGGGTTCG
GCGGCATGGTTTCGTTCACGGTCAAAGGGGGCCTGGAGGCCGTCCACCACATTCTGCGATCCACGCGCGTCTTCACGCTG
GCCGAATCGCTGGGCGGCGTCGAGTCGCTCATCGAGCATCCGGCCACGATGAGCCATGCGTCGATGCGCCCGGAACAACG
CGAGGCCGCCGGCATTACGGACAACCTGATCCGCCTGTCGGTCGGCATCGAGGCCACCGACGACCTGATCGCCGACCTGG
AACAGGCGCTGGCCTACGAACCGGCCACCGTTGCCGCCTGA

Protein sequence :
MQPQTRLTLAGQQTDSSYNSIVPPIYQCATFRFEDVGLTKGYDYSRSGNPTRRALEEVLADLEGGADAVATTSGMAAVST
VLALFDHGIHVICAHDCYGGTERLLSLLARQGKLEVSFVDLRDLQAVEAAIRPNTRLIWVETPSNPLLRIVDLDALCRFA
KAHDLLVVVDNTFLSPLQQRPMDFGADIVVYSTTKYLNGHSDVIGGAVIVRTGELNEQLQFVANAHGTIAGPFDCWLVLR
GLKTLPVRIRQHEHNAMAVARFLAQHPNVERVFYPGLPSHEGHEIAARQQKGFGGMVSFTVKGGLEAVHHILRSTRVFTL
AESLGGVESLIEHPATMSHASMRPEQREAAGITDNLIRLSVGIEATDDLIADLEQALAYEPATVAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-65 47
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-79 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-80 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rmar_1667 YP_003290941.1 cystathionine gamma-synthase BAC0207 Protein 3e-57 42