Gene Information

Name : Rmar_1388 (Rmar_1388)
Accession : YP_003290665.1
Strain : Rhodothermus marinus DSM 4252
Genome accession: NC_013501
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1621975 - 1623648 bp
Length : 1674 bp
Strand : -
Note : TIGRFAM: mercuric reductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; Heavy metal transport/detoxification protein; KEGG: sal:Sala_2683 mercuric reductase MerA

DNA sequence : 
ATGAAAAAGATCCTGGAACTGCGTATCGGGGGAATGACCTGCACGCATTGCGCGCGCACGATCGAACAGGCGCTCATGCG
GGTGCCCGGTGTGGTGCGCGCGCAGGTGCCCGGCTGGCAGAGCGGCCGGGCTGTAGTAACCTGGGAAGGCGACGCTGTCG
ATGCCGAAGCGCTCAGGAAGGCCGTCGCGCAGGCCGGCCACGGATACCGACTGGAGGCGTGGGAGGTGGTGCGTGAAATC
GGCAGCGAGACGCCGACCAGGAGCGGTTCGGATCGGATCGATTACGATCTGCTGATCATCGGCGGTGGCTCGGCGGCGTT
TGCGGCGGCGTTGCGGGCGCGGGAGCTGGGCTTCCGGAGCTTGATCGTCAACGACGGCCTGCCGCCGGGCGGCACGTGTG
TGAACGTCGGCTGCGTGCCCTCGAAGGCGCTTATCCGGGCGGCCGAAGCGCATCACCGGGCGGCGCATCATCCGTTTGCG
GGGATCCGTTCCACCAGTCGGGTGGAGGATTTCGGCGCTGTAATCGGCCAGGTGCAGGCGCTGACCGACGAACTGCGTCG
GCACAAGTACCTGGATCTCATCGACGGCCGGCAGATCGTCTTTCGCGAAGGGCGGGCGCGGCTGGCCGGTCCGACCGCCA
TTCAGGTGGGCGACGAAACGATCACGGGCCGGGCCGTGCTGATCGCGACAGGTTCTCGGACGGCGCTGCCGCCCGTTCCG
GGTCTGGCCGACGGCCCTTATCTCACCAACGAAACACTCTACCGGCTATCTGTGCTACCCGAGCACCTGATCGTACTGGG
CGGCGGCTACATCGGACTGGAAAACGCCCAGGCCTTTGCCCGGCTGGGCAGCCGGGTAACGGTGCTGGAGCTGTTGCCGC
AGATTCTCCCGCAGGAAGACGCCGACGTGGCCGAGGCGCTCACAACGTACCTGCAGGCAGAGGGCATCGACATTCAGACC
GAGGCGCGTGTCGTGGAGGTAGCCTGGCAGGAAGGCAGCGTGGTGGTCACATATGAACGAGATGGCGCGACGCATCGGCT
GGAGGGCTCGCATTTGCTGGTGGCGACCGGCCGCCGGGGCAACACGGACGATCTGGGCCTGGAGGCACTGGGCATAGCCA
CCGACCGCCAGGGTTTTCTGCAGGTGGACGAAACGCTGCGGACGGCGGTGCCGACCGTGCTGGGGGCCGGCGACGTGATC
GGCAATCCGCCGTTCGTGTACACGGCCGCCTACGAAGGCCAACTGGCCGCCGAAAATGCCCTGATGAATCGGCACGAGGT
GCGGGACTACAGCGCGCTACCCTGGGTGGTGTTCACCGATCCCCAGGTGGCCGGGGTGGGCCTGAGTGAGCGCGAGGCGC
AGGCGGCGGGCCTTGAATACGAAACGTCCGTGCTGCCGCTTTCGGAGGTGCCGCGGGCGCTGGTGGGCCGCGACACGCGC
GGGTTCATCAAGCTGCTGCGCGATCCGGTGACGGACCGACTGCTGGGCGCGCGGATCGTAGCCCCTGAGGGCGGCGAGCT
GGTCATGGAGCTGTCGCTGGCGCTGCGCTACGAGATCCCGGTCTCGGAGCTGGCCCGTCGGTTTCATCCCTATCTGACCT
GGTCCGAGGCCGTCAAACTGGCCGCGCTGGGCTTTACAAAGGATGTGCGCCAGCTCAGCTGCTGTGCCGTGTGA

Protein sequence : 
MKKILELRIGGMTCTHCARTIEQALMRVPGVVRAQVPGWQSGRAVVTWEGDAVDAEALRKAVAQAGHGYRLEAWEVVREI
GSETPTRSGSDRIDYDLLIIGGGSAAFAAALRARELGFRSLIVNDGLPPGGTCVNVGCVPSKALIRAAEAHHRAAHHPFA
GIRSTSRVEDFGAVIGQVQALTDELRRHKYLDLIDGRQIVFREGRARLAGPTAIQVGDETITGRAVLIATGSRTALPPVP
GLADGPYLTNETLYRLSVLPEHLIVLGGGYIGLENAQAFARLGSRVTVLELLPQILPQEDADVAEALTTYLQAEGIDIQT
EARVVEVAWQEGSVVVTYERDGATHRLEGSHLLVATGRRGNTDDLGLEALGIATDRQGFLQVDETLRTAVPTVLGAGDVI
GNPPFVYTAAYEGQLAAENALMNRHEVRDYSALPWVVFTDPQVAGVGLSEREAQAAGLEYETSVLPLSEVPRALVGRDTR
GFIKLLRDPVTDRLLGARIVAPEGGELVMELSLALRYEIPVSELARRFHPYLTWSEAVKLAALGFTKDVRQLSCCAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AGK07079.1 MerA Not tested SGI1 Protein 6e-70 42
merA ABQ57371.1 MerA Not tested SGI1 Protein 6e-70 42
merA AGK07021.1 MerA Not tested SGI1 Protein 6e-70 42
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 2e-67 41
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 7e-71 41
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 4e-68 41
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 1e-67 41
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 8e-68 41
merA AFG30120.1 MerA Not tested PAGI-2 Protein 8e-68 41
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 6e-68 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rmar_1388 YP_003290665.1 mercuric reductase BAC0650 Protein 2e-62 43
Rmar_1388 YP_003290665.1 mercuric reductase BAC0653 Protein 7e-72 42
Rmar_1388 YP_003290665.1 mercuric reductase BAC0649 Protein 2e-97 42