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Name : Gbro_0643 (Gbro_0643) Accession : YP_003271862.1 Strain : Gordonia bronchialis DSM 43247 Genome accession: NC_013441 Putative virulence/resistance : Virulence Product : AMP-dependent synthetase and ligase Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG1021 EC number : - Position : 703603 - 705525 bp Length : 1923 bp Strand : + Note : PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: scl:sce3880 (2,3-dihydroxybenzoyl)adenylate synthase DNA sequence : GTGGTCTCCACCGGTGGCAACCACTTAGGGTACCCAGACTATAGACTCGCTCGCGTGACTGGATATCCGCCTGACTTCGC TCGGCGTTACCGCGAGCGTGGTTACTGGATAGGGCAGACCCACACCGCGCTCCTCGAATCGGCTGCGGACGCCCACCCCG ACCGGGTTGCGGTGATCGACGATCGCCGGACGCTGACCTACCGGCAACTCCTCGACTCGTCCCGTTCCCTGGCGCACGGA TTCACCGGGCTCGGCCTGGACCCCGGCGCGCGTGTCGTGGTGCAGATGCCGAATGTCGGCGAGTACCTCGAGGTGGTGTT CGCCCTGTTCGACGCCGGTCTGATCCCGGTGTTCGCACTCGCCTCGCACGGCCGCGCCGAGATCGATGACCTGGTGACCC GCGCCGAAGCGTCGGCATATGTGACCGTCGACGCCTTCTCGGCCACGCGGTACGCCGACATCGCTGCGGCGATCCAGACC GCCCATCAGAGTGTCGCGGTCGTGGTCGCCCCGCTCGGTGGTTCCGACTCGCCGCTCCCGGACGGTGTTATCGGCCTCGA CGACCTCCGTACCGGCACCGCCGGCAGCACGGGACGGTCGTCGAGTCCGGCCGACATCGCGTTCTTGCAGCTCTCCGGCG GGACGACGGGCGTGCCGAAGCTCATCGGCCGTACCCACGACGACTACCTTTATTCGGTCCGGGAGAGCGCCCGGATCAGC GGATTGTCGCCCGAATCGGTGTTCGGGGTGGTCCTGCCGGTCTCGCACAACTTCACGATGAGCTCACCGGGTGTGCTCGG CGCGATCCACGCCGGCGCGAGGATCGTCATGGTGGGTTCACCCGACGCCGGCACCGTCTTCGGTGCTGTTGCGAGGCATC GGATCACCCATCTGTCCGCGGTGCCGCCGCTGGTGGCCGCCTGGCTGGACTCGCCGGCGCGCACCGCACACGACGTGTCG TCGTTGCAGGTCCTCCAGGTCGGCGGGGCCAAGCTGTCGCGGGCGTTGGCCGAGCGGGTGCCCGACGCATTCGGCGTGTG TCTGCAGCAGGTCTTCGGGATGGCCGAGGGACTGGTGAACTACACCCGGCTCGACGACGACGCGGAGACCATCGTCGACA CGCAGGGGCGCCCGATCAGTCCCGACGACGAGATCCGGGTGGTGGGGCCCGACGGTGGCGAGGTTCCCGACGGTAGCGCG GGGGCGTTGCAGACCCGTGGGCCGTACACCATCCGGAACTATTGGGGCGGAGTGTCGCCCGAGTCGTTCACCCCCGACGG CTTCTACATCACCGGCGACATCGTGGTGCGGGATGCGCGCGGCTACCTACGGGTCGTCGGCCGCGACAAGGACCAGATCA ACCGGGCCGGCGAGAAGATCGCGCCCGAGGAGGTGGAGAACCATCTGCTGAGCCACCCGGCGGTGCGGGACGCGTCGGTG GTGGGCGTCCCCGACGACCGGCTCGGTGAACACATCCGTGCCTACGTCATCCCCGCGTCGAGCGCCGGACAGGAATTGCC CGACGAGGTGGGTATCCGCGGGTATCTCCGCGAACGCGGGCTGGCCGCGTTCAAGATCCCCGACGAGATCCTGGTGGTCG ACGAGTTCCCGACGACGCCCGTGGGCAAGGTGAGCAAGAACGCGCAACGCGCCGACACTTCCGCGCCCGCACCGGACGCG GGTGTCGACCGGGACACCATTCTGGCCGACGTCGCAGAGAAACTCGGACTCGGCCCCGCCGCACTTTCGGGCACAATCCC GTTGGCCGACACCGGGATCGACTCGCTGGCACTGATGGCGTTGCTGGACAAGTGGCGGGCGCAGGGCGCGGCGGGCCTCG ACTTCGAGGAACTCGCGACCGCGGAGACCGTCGACGACCTGATCGCGGGAGTACTCGCGGCCCATGCCCGACGTGGCAGC TGA Protein sequence : MVSTGGNHLGYPDYRLARVTGYPPDFARRYRERGYWIGQTHTALLESAADAHPDRVAVIDDRRTLTYRQLLDSSRSLAHG FTGLGLDPGARVVVQMPNVGEYLEVVFALFDAGLIPVFALASHGRAEIDDLVTRAEASAYVTVDAFSATRYADIAAAIQT AHQSVAVVVAPLGGSDSPLPDGVIGLDDLRTGTAGSTGRSSSPADIAFLQLSGGTTGVPKLIGRTHDDYLYSVRESARIS GLSPESVFGVVLPVSHNFTMSSPGVLGAIHAGARIVMVGSPDAGTVFGAVARHRITHLSAVPPLVAAWLDSPARTAHDVS SLQVLQVGGAKLSRALAERVPDAFGVCLQQVFGMAEGLVNYTRLDDDAETIVDTQGRPISPDDEIRVVGPDGGEVPDGSA GALQTRGPYTIRNYWGGVSPESFTPDGFYITGDIVVRDARGYLRVVGRDKDQINRAGEKIAPEEVENHLLSHPAVRDASV VGVPDDRLGEHIRAYVIPASSAGQELPDEVGIRGYLRERGLAAFKIPDEILVVDEFPTTPVGKVSKNAQRADTSAPAPDA GVDRDTILADVAEKLGLGPAALSGTIPLADTGIDSLALMALLDKWRAQGAAGLDFEELATAETVDDLIAGVLAAHARRGS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ybtE | AAA93464.1 | yersiniabactin 2,3-dihydoxybenzoate-AMP ligase | Virulence | HPI | Protein | 2e-84 | 43 |
| ybtE | YP_853079.1 | yersiniabactin siderophore biosynthetic protein | Virulence | PAI IV APEC-O1 | Protein | 4e-84 | 43 |
| irp5 | YP_002346898.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 3e-84 | 43 |
| ybtE | NP_669710.1 | salicyl-AMP ligase | Virulence | HPI | Protein | 3e-84 | 43 |
| ybtE | NP_993003.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 3e-84 | 43 |
| ybtE | YP_070120.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 3e-84 | 43 |
| ybtE | CAA21394.1 | - | Virulence | HPI | Protein | 3e-84 | 43 |
| irp5 | YP_001006819.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 3e-83 | 42 |
| irp5 | CAA73130.1 | Irp5 protein | Virulence | HPI | Protein | 2e-83 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Gbro_0643 | YP_003271862.1 | AMP-dependent synthetase and ligase | VFG0168 | Protein | 6e-104 | 46 |
| Gbro_0643 | YP_003271862.1 | AMP-dependent synthetase and ligase | VFG0932 | Protein | 2e-93 | 43 |
| Gbro_0643 | YP_003271862.1 | AMP-dependent synthetase and ligase | VFG1817 | Protein | 1e-82 | 42 |
