Gene Information

Name : Gbro_4102 (Gbro_4102)
Accession : YP_003275160.1
Strain : Gordonia bronchialis DSM 43247
Genome accession: NC_013441
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4404877 - 4407429 bp
Length : 2553 bp
Strand : -
Note : KEGG: gme:Gmet_2851 ATPase AAA; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA; Clp ATPase-like; ATPase AAA central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA

DNA sequence :
GTGGACAGCTTCACCCCCACCACCAAGACACAGCAAGCGTTGAGTGCTGCTGTGCAGGCGGCGGCCAGCGCTGGAAATCC
CGACGTGCGACCGGCCCATATCCTTGTGGCCCTGCTCGATCAGTCCGACGGCATCGCGTCGCCGCTGCTCAAAGCGGTCG
GGGTGGACCCGTCGAATGTTCGTGCGCAGGCCCAGGCGATGGTCGATCGCATGCCGACGGTGTCCGGTGCCAGCTCGACG
CCACAACTCTCCCGCGAGTCGATCGCGGCCATCAGTGCCGCTCAGCAGCTTGCCGGTGAGCTCGACGACGAGTACGTCTC
CACCGAACACATGGTGGTCGGTCTGGCGACCGGCGACTCCGACGTCGCCAAACTGCTGCACAACGCCGGGGCCACCCCGC
AGGCGTTGCGCGAGGCCTTCGTCGCCGTGCGCGGCAACGCCCGGGTGACCTCGGAGGACCCCGAATCGACGTATCAGGCA
CTGGAGAAGTACTCCACCGACCTGACCGCCGCGGCCCGCGAGGGCAAACTCGACCCGGTCATCGGCCGGGACACCGAGAT
CCGGCGCGTCGTGCAGGTGCTCAGTCGCCGTACCAAGAACAACCCGGTGCTCATCGGTGAGCCCGGCGTCGGCAAGACCG
CCATCGTGGAAGGGCTGGCCCAGCGCATCGTCGCCGGGGACGTCCCGGAATCGTTGCGCGGCAAAACCGTCATCTCCCTG
GACATGGGCTCGATGGTGGCCGGCGCCAAGTACCGCGGCGAATTCGAGGAACGACTCAAGGCCGTCCTCGACGAGATCAA
GGGATCGGCCGGGCAGGTCATCACCTTCATCGACGAGTTGCACACCATCGTGGGTGCCGGCGCGACAGGCGATTCCGCGA
TGGATGCCGGCAACATGATCAAGCCGATGCTGGCTCGCGGTGAGCTGCGGCTGGTCGGCGCGACCACCCTCGAGGAGTAC
CGCAAGTACATCGAGAAGGACGCCGCCCTCGAGCGCCGCTTCCAGCAGGTGTACGTCGGTGAACCCTCCGTCGAGGACGC
CATCGGCATCCTGCGTGGCCTGAAGGATCGGTACGAGGTGCACCACGGTGTGCGCATCACCGACTCCGCCCTGGTGGCCG
CGGCAACGCTGTCCGACCGCTACATCACCTCCCGCTTCTTGCCGGACAAGGCCATCGACCTCGTCGACGAGGCCGCGTCG
CGACTGCGGATGGAGATCGACTCGCGCCCCGTCGAAATCGACGAGGTGGAGCGCATTGTTCGCCGTCTGGAGGTCGAAGA
GGTTGCGCTGCAGAAGGAAACGGACGCCGCATCCAAGGAGCGGCTGGAGAAGCTGCGTCAGGAACTGGCCGACCAGAAGG
AAAAGCTCAACGAGCTGAGCGCCCGCTGGCAATCGGAGAAGACCGCCATCGACGCGGTCCGCGACCTCAAGGAAGAGCTG
GAACGGCTTCGCGGAGAGGCAGATCGGGCCGAGCGTGACGGCGATCTGGGCCGTGCGGCCGAACTGCGGTACGGCAAGAT
CCCCGGACTCGAGAAGAACCTCGAGGCCGCGATCGAGAAGACCGGCACCGATCCCGGGCAAGACGTGATGCTCCAGGAGG
AGGTCGGCCCCGACGACGTGGCGCAGGTCGTGTCGTCGTGGACCGGAATCCCTGCCGGGCGCATGCTCGAAGGTGAGACC
GCCAAGCTGCTGCGCATGGAAGAGGAACTGGGACACCGGGTCATCGGCCAGAAGGCGGCTGTGGTCGCGGTCTCCGACGC
CGTGCGCCGCGCCCGTGCCGGGGTCGCCGACCCCAACCGGCCGCTGGGTTCGTTCATGTTCCTCGGCCCGACCGGCGTCG
GCAAGACCGAGCTGGCCAAAGCGCTCGCCGAGTTCCTGTTCGACGACGAGCGGGCGATGGTCCGCATCGACATGAGCGAG
TACGGCGAGAAGCACAGCGTGGCAAGACTTGTGGGTGCCCCTCCCGGTTACGTCGGCTACGAGGCCGGCGGTCAGCTGAC
CGAGGCGGTGCGGCGTCGGCCGTACACGGTGGTGCTGTTCGACGAGATCGAGAAGGCCCACCCGGACGTCTTCGACGTGC
TGCTGCAGGTCCTCGACGAGGGTCGCCTGACCGATGGTCAGGGTCGCACGGTGGACTTCCGCAACACCATCCTCGTCCTC
ACGTCCAACCTGGGCGCGGGCGGCGACAAGGATCAGGTGATGGCGGCGGTCCGCAGCCGGTTCAAGCCGGAGTTCATCAA
CCGGCTCGACGACGTCATCATCTTCGACGCGCTGAGCCCCGAGGAACTGGTGTCCATCGTCGACATCCAGCTCGCCCAGC
TCGGTAAGCGGCTGGCACAGCGTCGGCTGGAACTGCAGGTCACGCCGAAGGCCAAGGAATGGCTCGCCGAGCGCGGATTC
GATCCGCTCTACGGTGCGCGGCCACTGCGCCGGCTGGTGCAGCAGGCCATCGGCGACAGCCTCGCCAAGGCGTTGCTGGC
CGGCGACATCCGCGACGGCGATGTGGTGCCGGTGAACGTCAGCGCCGACGGAGAGTCGTTGGTGCTCGGCTGA

Protein sequence :
MDSFTPTTKTQQALSAAVQAAASAGNPDVRPAHILVALLDQSDGIASPLLKAVGVDPSNVRAQAQAMVDRMPTVSGASST
PQLSRESIAAISAAQQLAGELDDEYVSTEHMVVGLATGDSDVAKLLHNAGATPQALREAFVAVRGNARVTSEDPESTYQA
LEKYSTDLTAAAREGKLDPVIGRDTEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRGKTVISL
DMGSMVAGAKYRGEFEERLKAVLDEIKGSAGQVITFIDELHTIVGAGATGDSAMDAGNMIKPMLARGELRLVGATTLEEY
RKYIEKDAALERRFQQVYVGEPSVEDAIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITSRFLPDKAIDLVDEAAS
RLRMEIDSRPVEIDEVERIVRRLEVEEVALQKETDAASKERLEKLRQELADQKEKLNELSARWQSEKTAIDAVRDLKEEL
ERLRGEADRAERDGDLGRAAELRYGKIPGLEKNLEAAIEKTGTDPGQDVMLQEEVGPDDVAQVVSSWTGIPAGRMLEGET
AKLLRMEEELGHRVIGQKAAVVAVSDAVRRARAGVADPNRPLGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSE
YGEKHSVARLVGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILVL
TSNLGAGGDKDQVMAAVRSRFKPEFINRLDDVIIFDALSPEELVSIVDIQLAQLGKRLAQRRLELQVTPKAKEWLAERGF
DPLYGARPLRRLVQQAIGDSLAKALLAGDIRDGDVVPVNVSADGESLVLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-98 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Gbro_4102 YP_003275160.1 ATP-dependent chaperone ClpB VFG2076 Protein 1e-106 44
Gbro_4102 YP_003275160.1 ATP-dependent chaperone ClpB VFG2084 Protein 6e-108 43