Gene Information

Name : Gbro_3822 (Gbro_3822)
Accession : YP_003274893.1
Strain : Gordonia bronchialis DSM 43247
Genome accession: NC_013441
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 4108258 - 4109754 bp
Length : 1497 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: bmj:BMULJ_04931 NAD-dependent aldehyde dehydrogenase

DNA sequence :
ATGACCGCCGTCGCCACCGAATTGCTCCCGAGGATCCGAGACTTCATCTCCGCCGACCGATCCATGCTGATCGGCGGGGA
ATGGGTCTCGGCCGCCTCCGGGCGCACCTTCGAGACCATCGACCCGGCCACCGCTCGGCCGATCACCTCGGTGGCGCACG
GCGAGGCCACCGACGTCGACCGCGCGGTCCGAGCCGCACGCCGCGCCTTCGACGAAGGTCCCTGGGCGTCGATGAAGCCG
AACGAGCGGGAACGACTGCTCTGGCGGGTCGGCGACCTCCTCACCGAACGCGCCGCAGAGTTCGGGCAGCTCGAGGCGCT
CGACAACGGCAAGGCCGCGACCATCGCCTCCGCGGTCGACGTGTCGTGGTCGGCGGACATCTTCCGCTACAACGCCGGCC
TGGCCACCAAGATCACCGGCTCGACGGTCGACGTGTCGATGCCGTTCGTGCCGGGCGGCGAGTTCCACGCGTACACGCTG
CGGGAGCCGGTCGGCGTCTGCGGGCTCATCGTGCCGTGGAACTTCCCGTTGCTGATGGCGGCGTTCAAACTGGCACCCGC
GCTGGCCGCCGGAAACACGGTGATCCTCAAGCCCGCCGAACAGACACCGCTCACCGCACTGCTGCTCGGCGAGATCTTCG
AGGAGGCCGGATTCCCGCCCGGTGTGGTCAACATCGTCACCGGTTTCGGCGACGCGGGGGCCGCGCTGGCCGCCCACGAC
GACGTCGACAAGATCGCATTCACCGGTTCCACCGAGGTCGGCAAGAAGATCGTCGAGGCCGCCAAGGGCAATCTGAAGAA
GGTCTCCCTGGAACTCGGCGGGAAGAGCCCCAACATCGTGTTCGCCGACGCCGACTTCGAGAAGGCGGTCGCCGGTTCGG
TGGCCGCGTGGATGTTCAACCACGGCCAGTGCTGCGTGGCCGGCACCCGACTTTTCGTGGAACGCCCGATCTTCGACGAC
TTCACCGCGGCAGTCGCCGAGGCCGCATCGCAGGCCAAGATCGGCCCGGGCCTGGACCCCGCCACCGAACTCGGTCCGCT
GGTCAGCCAGGAGCAGTTCGACCGCGTCAGCGGCTACCTGTCGGCCGGACTCGCCGACGGCGCCCGTGCCCTGACCGGCG
GAAAGCGTTGGGGCGATGAGGGATTCTTCATCGAGCCGACCGTCTTCGTCGACGTCGAGCCACATTTCTCGATCGTGACC
GAGGAGATCTTCGGGCCCGTCGTCGCAGCACTGCCCTTCGACGCCGACACCGGCGTCGCGGCCGCCGCCAACGACTCCAT
CTACGGTCTGGCCGCGGGCATCTGGACACAGGACCTGTCCAAGGCGCACAAGACCGCGCGGGCGATCAAGGCCGGTTCGG
TGTGGGTCAACCAGTACAACGGCTTCGACACCGCCATGCCCTTCGGCGGCTACAAGCAGTCCGGCTGGGGACGCGAACTG
GGGTCGTCGGCCATCGACCTGTACACGCAGACCAAGGCCGTCAACATCGCCCTCTGA

Protein sequence :
MTAVATELLPRIRDFISADRSMLIGGEWVSAASGRTFETIDPATARPITSVAHGEATDVDRAVRAARRAFDEGPWASMKP
NERERLLWRVGDLLTERAAEFGQLEALDNGKAATIASAVDVSWSADIFRYNAGLATKITGSTVDVSMPFVPGGEFHAYTL
REPVGVCGLIVPWNFPLLMAAFKLAPALAAGNTVILKPAEQTPLTALLLGEIFEEAGFPPGVVNIVTGFGDAGAALAAHD
DVDKIAFTGSTEVGKKIVEAAKGNLKKVSLELGGKSPNIVFADADFEKAVAGSVAAWMFNHGQCCVAGTRLFVERPIFDD
FTAAVAEAASQAKIGPGLDPATELGPLVSQEQFDRVSGYLSAGLADGARALTGGKRWGDEGFFIEPTVFVDVEPHFSIVT
EEIFGPVVAALPFDADTGVAAAANDSIYGLAAGIWTQDLSKAHKTARAIKAGSVWVNQYNGFDTAMPFGGYKQSGWGREL
GSSAIDLYTQTKAVNIAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-64 46
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-60 42
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-63 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-63 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-63 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-63 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Gbro_3822 YP_003274893.1 aldehyde dehydrogenase VFG0082 Protein 1e-60 42