Gene Information

Name : Gbro_2755 (Gbro_2755)
Accession : YP_003273866.1
Strain : Gordonia bronchialis DSM 43247
Genome accession: NC_013441
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 2938628 - 2940346 bp
Length : 1719 bp
Strand : -
Note : KEGG: ank:AnaeK_0975 urease subunit alpha; TIGRFAM: urease, subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein; amidohydrolase

DNA sequence :
ATGGCATCACTCGGTCGTGACCGCTACGCGGCGCTGTTCGGCCCCACCACCGGCGACCGGATCCGGCTCGCGGATACCGA
CCTGCTGATCGAGGTCACCGAGGATCGCTCCGGCGGCCCGGGACGCGCGGGTGACGAGGCCGTCTTCGGTGGCGGCAAGG
TGATCCGCGAGTCGATGGGGCAGAGCCGCGCGACCCGCGCCGACGGCGCCCCCGACACGGTGATCACCGGCGTGGTGGTC
CTTGATCACTGGGGAATCATCAAGGCGGACCTAGGGATTCGGGACGGCCGGATCGTCGCGCTGGGCAAGGCGGGGAACCC
GGACACGATGGACGGCGTCCACCCAGATCTCGTGATCGGGCCGTCCACCGAGATCGTCGCCGGCAACGGCAAAATCGTCA
CGGCCGGCGGGATCGACTGTCACGTCCACTTCATCTGTCCGCAGATCATGGACGAGGCGCTCGGCAACGGCATCACTACC
CTGATCGGCGGTGGCACCGGTCCCGCCGAGGGGAGCAAGGCCACCACCGTCACCCCGGGTGCCTGGCATCTCGCCTCGAT
CCTGGCCGCTACCGATCACTGGCCGATGAACATCGCCCTGCTCGGTAAGGGCAACACGGTCAGTGCCGAGGCGATGTACG
AGCAGATCCGGGCCGGCGCATCGGGATTCAAACTTCATGAGGACTGGGGCAGCACCCCGGCCGCGATCGATGCGTGCCTG
CGGGTCGCCGACGAGACCGGTGTCCAGGTCGCGTTGCACTCCGACACCCTGAACGAGGCCGGATTCGTCGAGCAGACCCT
CGCCGCCATCGCCGGCCGCGGCATCCACGCCTACCACACCGAAGGCGCCGGTGGTGGGCATGCGCCCGACATCATCACGG
TCGCAGCACATCCCAACGTCCTGCCGAGTTCCACCAATCCCACCCGCCCGCACACCGTCAACACGCTCGACGAGCATCTC
GACATGCTCATGGTGTGTCATCACCTCAACCCGACCGTGCCGGAGGATCTCGCCTTCGCCGAAAGTCGTATCCGGCCGTC
CACCATCGCCGCGGAGGACCTGCTGCACGACCTCGGCGCCATCTCGATGATCGGATCGGACGCCCAGGCGATGGGCCGGA
TCGGTGAGGTGGTGTTGCGCACCTGGCAGACCGCGCACGTCATGAAGCGCAAACGCGGTGCGCTCGACGGCGATGGCCCG
GCCGACAACCTCCGCGCCCGCCGCTACGTCGCGAAGTACACGATCTGCCCCGCCATCGCGCACGGCTTCGACGACGAGAT
CGGCTCGGTCGAGGTGGGCAAGCTCGCCGACCTCGTCGTCTGGGACCCGGTGTTCTTCGGTGTCCGACCAGATCTCGTCA
TCAAGGGCGGTGCCATCGCGTGGGCGGCCATGGGTGATGCCAACGCGTCCATTCCCACCCCGCAGCCGGTGCTGGGGCGG
CCGATGTTCGGCGCGGCGGGCAAGGTTGCCGCGGCCACGTCGGTCAGCTTCGTCGCGCCCGGAGCCGACGACGGCCTGGC
CGATCGGATCGGTGTCGACCGAAAACTGGTGCCCGTCAAGAACACTCGGAGCCTCGGCAAGGCGGACATGCCAGGCAACG
ACGCCTGCCCGCGAATCGAGGTCGAACCCGACACCTTCACCGTGCGCATCGACGGTGAGGTGTGGGATTCACCGCCGATG
GACCGGTTGCCGATGGCGCAGCGGTATTTCCTGTTCTGA

Protein sequence :
MASLGRDRYAALFGPTTGDRIRLADTDLLIEVTEDRSGGPGRAGDEAVFGGGKVIRESMGQSRATRADGAPDTVITGVVV
LDHWGIIKADLGIRDGRIVALGKAGNPDTMDGVHPDLVIGPSTEIVAGNGKIVTAGGIDCHVHFICPQIMDEALGNGITT
LIGGGTGPAEGSKATTVTPGAWHLASILAATDHWPMNIALLGKGNTVSAEAMYEQIRAGASGFKLHEDWGSTPAAIDACL
RVADETGVQVALHSDTLNEAGFVEQTLAAIAGRGIHAYHTEGAGGGHAPDIITVAAHPNVLPSSTNPTRPHTVNTLDEHL
DMLMVCHHLNPTVPEDLAFAESRIRPSTIAAEDLLHDLGAISMIGSDAQAMGRIGEVVLRTWQTAHVMKRKRGALDGDGP
ADNLRARRYVAKYTICPAIAHGFDDEIGSVEVGKLADLVVWDPVFFGVRPDLVIKGGAIAWAAMGDANASIPTPQPVLGR
PMFGAAGKVAAATSVSFVAPGADDGLADRIGVDRKLVPVKNTRSLGKADMPGNDACPRIEVEPDTFTVRIDGEVWDSPPM
DRLPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-155 61
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-155 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-153 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-153 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-153 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-153 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Gbro_2755 YP_003273866.1 urease subunit alpha VFG0270 Protein 2e-140 55