Gene Information

Name : Gbro_1618 (Gbro_1618)
Accession : YP_003272782.1
Strain : Gordonia bronchialis DSM 43247
Genome accession: NC_013441
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1688644 - 1689795 bp
Length : 1152 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: pol:Bpro_2831 cystathionine gamma-lyase

DNA sequence :
GTGAGCCAAGCCTTTTCGACCGGCTTCTCGACCCGCGCCATCCACGCCGGCTACGAGCCGGACCCGCAGACCGGTGCGGT
CAACGTGCCGATCTACGCGAGTTCCACGTTCGCCCAGGACGGTGTCGGCGGACTGCGCCAGGGATTCGAGTACGCGCGTA
CCGGTAACCCCACTCGACGTGCGCTCGAGGCCAACCTCGCCGCACTGGAGAACGGAACCCACGGGCGCGCCTTCGGTTCC
GGCATGGCCGCCACCGACACCCTGCTGCGTGCGACGCTGCGTCCCGGCGATCACCTCGTCATCCCGAACGACGCCTACGG
CGGTACCTTCCGGCTCATCGACAAGGTCTTCACCCAGTGGGGCATCACCTATTCCGTCGCCCCGGTCACCGACGTCGACG
CCGTACGCGCCGCCATCCGGCCGGAGACCAAGCTGGTCTGGACCGAGACACCCACCAACCCGCTGCTCAACGTTGGTGAC
ATCGAGGCGCTGGCCTCGGTGGCCCACGATGCGGGTGCAAAGCTGGTGGTGGACAACACCTTCGCTTCCCCGTATCTGCA
GCAGCCGTTGTCGCTGGGCGCGGATGTGGTGCTGCATTCGACCACCAAGTATCTCGGCGGGCACTCCGATGTGGTCGGTG
GTGCGCTGATCACCGACTCGACCGAACTCGACGAGGCGTTCGCGTTCCTGCAGAACGGGGCCGGTGCGGTACCCGGACCG
TTCGACGGATACCTGACCCTGCGCGGCATCAAAACCCTTGCGGTGCGGATGGATCGGCACTGCGACAACGCCGAGAAGGT
CGTCGAGTTCCTGAGCGGGCACGACAAGATCGACGCCGTGCTCTACCCGGGTCTTTCGACACATCCCGGGCACGGCGCCG
CGGCCAAGCAGATGAAGCGGTTCGGCGGAATGGTGTCGGTGCTGGTCAAGGACGGAATGGATGCGGCGCAGAAGTTCTGT
GCCCGCACCGAGGTGTTCACCCTCGCCGAGTCGCTCGGCGGCATCGAGTCGCTGATCGAGCATCCGGGCGCGATGACGCA
CGCCTCGACGGCCGGGTCGCTGCTGGAGGTCCCGGAGAACCTGGTGCGACTCTCGGTGGGTATCGAGGACATCGACGACA
TCCTCGCCGACCTGGACAACGCACTCGCCTGA

Protein sequence :
MSQAFSTGFSTRAIHAGYEPDPQTGAVNVPIYASSTFAQDGVGGLRQGFEYARTGNPTRRALEANLAALENGTHGRAFGS
GMAATDTLLRATLRPGDHLVIPNDAYGGTFRLIDKVFTQWGITYSVAPVTDVDAVRAAIRPETKLVWTETPTNPLLNVGD
IEALASVAHDAGAKLVVDNTFASPYLQQPLSLGADVVLHSTTKYLGGHSDVVGGALITDSTELDEAFAFLQNGAGAVPGP
FDGYLTLRGIKTLAVRMDRHCDNAEKVVEFLSGHDKIDAVLYPGLSTHPGHGAAAKQMKRFGGMVSVLVKDGMDAAQKFC
ARTEVFTLAESLGGIESLIEHPGAMTHASTAGSLLEVPENLVRLSVGIEDIDDILADLDNALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-68 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-70 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-49 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Gbro_1618 YP_003272782.1 cystathionine gamma-synthase BAC0207 Protein 5e-61 42