Gene Information

Name : Gbro_0127 (Gbro_0127)
Accession : YP_003271369.1
Strain : Gordonia bronchialis DSM 43247
Genome accession: NC_013441
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 142798 - 146214 bp
Length : 3417 bp
Strand : +
Note : KEGG: sml:Smlt2232 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); protein of unknown function DUF472; protein of unknown function DUF471; protein of unknown function DUF470; nucleic acid binding OB-fold

DNA sequence :
ATGGCTCTCGACACCCCTTCGTCGGACCTCCCGGTCAGCACCGACGACACTGCTGAGCACCAGCCCACCCCAGCGCACCG
TCCGCCGTCGGCGGCCGATCGCCGATCCGTCGACCTGCTCGAAAAGATCAGGCGGCCCAGAGGATTCGGGGCCGGCGCAC
CCAAGATCGCGGGCACTGTGGTCGGCGTGCTGGCCGGCATCGCGCTGTTGTCGAGCATCTTCCCGCTGTTCCGCCGGCTG
ATCCACTACCCGCGCGACTTCATCGACAACTACATCGTCTCGCTGCCCAACACGAGTCTGGCGTGGGCCTTCGTGCTGGC
GCTGGTCGCGATCGCACTGTCGTCACGCAAACGCATCGCGTGGTGGATCGCGACGATCTACCTGGTGCTGTTCATGGTGA
GCAATGCGCTGCTGCTCGTCGATCCGGTGGCCACCGACTTCGGCGTCGACACCGACGAACGCATCCAGATCTGGATCGGA
CTGGGAATCGATGCGGCCGCACTCATCTTCCTGATCGTCACCTACCGGCAGTTCTACACACGTGTCCGCCGCGGCGCCCT
CTTCCGGGCCCTCGGTGTGCTCATCGTCGGACTCACCGCCGCCACCCTCGTCGGATGGGGTCTGGTGTGGGCGTGGCCGG
GGAGTCTGGAGCGGACCGAACGCCTGCCGTACGCGTTCAACCGGGTGGTCACCTTCGGCAGCATCGACAGCCGAACCTTC
GACGGTCACCACACCCACATCGTCATCGACAGTGCACTGGGGCTGCTCGGGGCGCTGGCCCTTATCGCCGCGGCGACGGT
GCTGTTCCGCTCACAGCGACTGGAATCGTTGATGACCAGCGACGACGAGAAGCTGATCCGCGCACTGATCACCCGATTCA
ACGACGACGATTCGCTGGCCTACTTCTCCACCCGCCGCGACAAGGCGGTGGTGTTCTCACCCGACGGCCGGGCCGCGATC
ACCTACCGCGTGGAGATCGGCGTCGGACTGGCCGGCGGCGACCCGATCGGAGATCCGGAATCCTGGCCCGACGCCATCGC
CGAGTTCCTCACGTTGTGCGATCGGTATGGCTGGCATCCGGCGGCGATGGGGTCGAGTGCGCGGGGCGCGGCCGCCTACG
ATGCGGCCGGATTCGGCTCGCTCTCCATCGGCGACGAAGCCATCCTGCACACCCGCGAGTACACGATCAGCGGACCCGCG
ATGAAGGCGGTGCGGCAGGCCGTGACGCGCACCCGCCGCGCCGGGGTGACGGTGCGGATTCGACGGCACGGCGAGGTGCC
CGACGATGAGATGCCACAGGTCATCGCCCGGGCCGATGCGTGGCGGGACACCGACGAGGAACGCGGCTTCGCGATGGCGC
TCTCGCGGCTCGGTGACCGTGCCGACGACGACTGCCTGCTGGTGGAGGCCGTCGAACATGCGGGCACCCCCGAGGAGAAG
GTGATCGGGATGCTCTCGTTTGTGCCGTGGGGCCGACGAGGTGTCTCGCTGGATGTGATGCGACGCGATCGTGGCAGCGT
GAACGGCGTCGTCGAGACGATGGTCACCGAATTGTGCCGCAACTCCGAGCAATTCGGTATCACCGAGATCTCGCTGAACT
TCGCCACCTTCCGCGCCTTCTTCGAGCAGGGCCCGCAGATCGGGGCCGGGCCCATCATGCGGCTCGGCTACTCGGTGCTC
ATGTTCGGCTCACGGTTCTTCCAGATGGAGTCGCTGTACAAGTCGAACGCCAAATATCTGCCGGACTGGCAGCCCCGGTT
CCTGTGCTTCGAGGACAACCGAATCCTGCCGCGCGTCGGGCTGGCCGCCATCGTCACCGAGGGCTTCGTGCAGCTGCCGA
GGTTCGGGCGCAAGCAGCATTACATCGCAGGTCAGTCGTCGATTCCGGCCGGAGTCGACGCCGACGCATTGATCGCGCAG
CTGGAGTCCGAGGAGGACCGCACGGCCGTCGAGGTGCACCGGCCTGAGCAGGTACGGGTGCGCGTCGCCAAGCTCGACCG
GCTGATCGAGGAGGGCTTCGACCCGTACCCGCCCGCCGATGCGCCGACACACACGATTGCCGAGGCGATCGCCGAGCCGG
AGGGCACGCAGGTCACCATCGCCGGACGGGTCACCAAGATGCGCGACTTCGGCAAGGTCACCTTCGCCGATGTGCACGAC
TGGTCCGGGCAGATACAGATGCTCGTCGAGGCGTCGCGGGTTATCCCGGGCACCCCCGACTTCGGATCCGACGTCGACCT
CGGCGACCTCGTCGAGGCACGTGGGGTGATCGGGCGGAGCCGGTCCGGGGAACTGTCGGTGCTGATCGATGCGTGGCGCT
TCAACGGCAAATGCCTGCGGCCGCTGCCCGATAAGTGGTCCGGACTCACAGACCCGGAAGCCCGTGTGCGGCAACGCTAT
GTGGACCTTGCGATCAACCCGCGCAGCCGTGAGCTGCTGGCCACCCGGAGTGTGGTGGTCAAGGCGCTGCGGGATTTCCT
CGCCGACCGCGGATTCATGGAGGTCGAGACGCCCATCCTGCAGCAGATTCACGGCGGGGCGAATGCCACCCCGTTCCAGA
CCCACATCAACGCCTACAACCTGGATCTGTATCTGCGGATCGCGCCGGAGTTGTATCTCAAGCGGCTGTGTGTCGGCGGC
GTCGAGAAGGTGTTCGAGATCGGTCGCAACTTCCGCAACGAGGGTGTCGACTTCAGTCACAACCCCGAGTTCACCAGCCT
GGAAGCCTATGCGGCACACAGCGATTACCTGAAGATGCTGGACCTGACGCGGGAAATGATCCAGCACGCAGCGACTGCCG
CGCACGGCGAGCCGGTGATCATCCGCGTCGACGACGAGGGCAACGAGCAGCGCGTCGACATCTCCGGTGACTGGCCGGTC
CGGACCGTGCACGAGGTGGTGTCGGAAGGCGCCGGTGTCGAGATCACATCGGACACAGAGGTTTCCGAGCTTCGCGGCAT
TTGCGATCGTCTGGAGATCGCCTACCGGCCGGACTGGGATGCCGGGCAGATCGTGCTGGAACTCTACGAGCATCTCGGCG
AGGATCGCACCACCGTCCCGACGTTCTACACCGATTTCCCCACGTCGACGTCGCCGCTGACCCGGGCGCACCGCAGCAAA
CCCGGCGTGGCCGAGCGCTGGGATCTGGTGGCCTGGGGGGTGGAACTCGGTACCGCGTACACCGAGCTGACCGATCCGGT
CGAGCAACGCAAACGGCTGACCGCACAGTCGATCCTGGCCGCCGACGGTGATCCGGAGGCGATGGAGTTGGACGAGGACT
TCCTCACCGCCCTCGAGTATGCGATGCCGCCCACCGGTGGTCTCGGCGTCGGGGTGGATCGGGTGGTCATGCTCATCACC
GGGCAGTCGATTCGTGAGTCGCTGGCGTTTCCGATGGTCAAGCCGACGGACGCGTGA

Protein sequence :
MALDTPSSDLPVSTDDTAEHQPTPAHRPPSAADRRSVDLLEKIRRPRGFGAGAPKIAGTVVGVLAGIALLSSIFPLFRRL
IHYPRDFIDNYIVSLPNTSLAWAFVLALVAIALSSRKRIAWWIATIYLVLFMVSNALLLVDPVATDFGVDTDERIQIWIG
LGIDAAALIFLIVTYRQFYTRVRRGALFRALGVLIVGLTAATLVGWGLVWAWPGSLERTERLPYAFNRVVTFGSIDSRTF
DGHHTHIVIDSALGLLGALALIAAATVLFRSQRLESLMTSDDEKLIRALITRFNDDDSLAYFSTRRDKAVVFSPDGRAAI
TYRVEIGVGLAGGDPIGDPESWPDAIAEFLTLCDRYGWHPAAMGSSARGAAAYDAAGFGSLSIGDEAILHTREYTISGPA
MKAVRQAVTRTRRAGVTVRIRRHGEVPDDEMPQVIARADAWRDTDEERGFAMALSRLGDRADDDCLLVEAVEHAGTPEEK
VIGMLSFVPWGRRGVSLDVMRRDRGSVNGVVETMVTELCRNSEQFGITEISLNFATFRAFFEQGPQIGAGPIMRLGYSVL
MFGSRFFQMESLYKSNAKYLPDWQPRFLCFEDNRILPRVGLAAIVTEGFVQLPRFGRKQHYIAGQSSIPAGVDADALIAQ
LESEEDRTAVEVHRPEQVRVRVAKLDRLIEEGFDPYPPADAPTHTIAEAIAEPEGTQVTIAGRVTKMRDFGKVTFADVHD
WSGQIQMLVEASRVIPGTPDFGSDVDLGDLVEARGVIGRSRSGELSVLIDAWRFNGKCLRPLPDKWSGLTDPEARVRQRY
VDLAINPRSRELLATRSVVVKALRDFLADRGFMEVETPILQQIHGGANATPFQTHINAYNLDLYLRIAPELYLKRLCVGG
VEKVFEIGRNFRNEGVDFSHNPEFTSLEAYAAHSDYLKMLDLTREMIQHAATAAHGEPVIIRVDDEGNEQRVDISGDWPV
RTVHEVVSEGAGVEITSDTEVSELRGICDRLEIAYRPDWDAGQIVLELYEHLGEDRTTVPTFYTDFPTSTSPLTRAHRSK
PGVAERWDLVAWGVELGTAYTELTDPVEQRKRLTAQSILAADGDPEAMELDEDFLTALEYAMPPTGGLGVGVDRVVMLIT
GQSIRESLAFPMVKPTDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-154 43
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 5e-155 43
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 5e-155 43
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 5e-155 43