Gene Information

Name : Hoch_6707 (Hoch_6707)
Accession : YP_003271064.1
Strain : Haliangium ochraceum DSM 14365
Genome accession: NC_013440
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 9203470 - 9204642 bp
Length : 1173 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: acp:A2cp1_3847 cystathionine gamma-lyase

DNA sequence :
ATGGGCTCTCGTCCGCCTTCCCACGGCTTTGGCACCCGCGCCATCCACGCCGGCCAATCCCCTGACCCCAGCACCGGCGC
GATCATGACGCCGGTCTACATGACCTCCACCTACGTGCAGAGCACGCCGGGGGAACACAAGGGCTTCGAGTACTCGCGCA
CGCAGAACCCGACCCGTTCGGCGCTCGAGGCCAACCTCGCCGCGCTCGAGGGCGCGCGCCACGGGCTGGCCTTCGCCTCC
GGTCTGGCCGCGACCTCGACCGCGCTGCAGCTCCTGTCGGCGGGCGATCACGTGGTCGCCTGCGATGACCTCTACGGCGG
CACCTATCGCCTCTTCGACAAGGTGTATCGCCGCTTCGGGCTGTCCTTCGACTACGTGGATCCCAGCGCGGGTCCCAGCG
CCGTCGAGGCCGCGCTCACCGACGCGACCCGCATGGTGTGGCTGGAGACGCCGACCAACCCGATGCTCAAGCTGTGCGAC
ATCGCGGCCGTGGCCGAGCTGTGCAAGCGGCGCGGGCTGCTGCTGGCGGTCGACAACACTTTCCTCACGCCCTTCAACCA
GAACCCGCTGGCCCTGGGCGCGGACCTGGTCTGTCACTCGACGACCAAGTACCTCAACGGCCACTCCGACACCGTCGGCG
GCGCGCTCATCACCGATAACGACGAGCTGCACGAGAAGCTCGCGTTCCTGCAGAACGCGGTCGGCGCGGTGCCCTCGCCC
ATGGACTCGTTCCTGGTCATGCGCGGGCTCAAGACCCTGCACGTGCGCATGGAGCGGCACGAGCGCAACGCGCGCGCGCT
GGCCGAGTGGCTCGTGGGACACGAGCAGGTCGAGCGCGTCATCTACCCCGGCCTCGAGAGTCACCCGCAGCACGAGCTGG
CCAAGCGCCAACAGCGCGGCTTCGGCGGCATGATCAGCTTCGATCTGCGCGGCGGCGAGCCGGCTGCGCGGCGCTTCCTC
GAGACCTGCGAGCTGTTCTCGCTGGCTGAGTCGCTCGGCGGTGTCGAGTCATTGGTCGAGCATCCGGCCATTATGACCCA
CGCCAGCGTGCCGGCCGAGCGCCGTCGCGCGCTCGGGATCGGCGATGGCTTCATCCGCCTGAGCGTCGGCATCGAAGAGC
TGGACGACCTCCGTGGTGATCTAGAACGCGCTTTTTTCGCCGCCCGCTCCTGA

Protein sequence :
MGSRPPSHGFGTRAIHAGQSPDPSTGAIMTPVYMTSTYVQSTPGEHKGFEYSRTQNPTRSALEANLAALEGARHGLAFAS
GLAATSTALQLLSAGDHVVACDDLYGGTYRLFDKVYRRFGLSFDYVDPSAGPSAVEAALTDATRMVWLETPTNPMLKLCD
IAAVAELCKRRGLLLAVDNTFLTPFNQNPLALGADLVCHSTTKYLNGHSDTVGGALITDNDELHEKLAFLQNAVGAVPSP
MDSFLVMRGLKTLHVRMERHERNARALAEWLVGHEQVERVIYPGLESHPQHELAKRQQRGFGGMISFDLRGGEPAARRFL
ETCELFSLAESLGGVESLVEHPAIMTHASVPAERRRALGIGDGFIRLSVGIEELDDLRGDLERAFFAARS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-74 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-76 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-50 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hoch_6707 YP_003271064.1 cystathionine gamma-lyase BAC0207 Protein 5e-58 47