Gene Information

Name : Hoch_4428 (Hoch_4428)
Accession : YP_003268815.1
Strain : Haliangium ochraceum DSM 14365
Genome accession: NC_013440
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 6062733 - 6064148 bp
Length : 1416 bp
Strand : +
Note : KEGG: mxa:MXAN_6299 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta

DNA sequence : 
ATGCGACGCGCCAAGATCGTGTGCACCCTGGGTCCGGCCTCTTCGACGCCAGAGCGTATCGGCGAGCTCATCGAAGCCGG
TATGAACGTGGCCCGTTTGAACTTCTCCCACGGTGACCACGAAGGTCACGCGAAGATGCTGCATACCATCCGCAGCGAGG
CCGAGCGCCGCGGCAAACCGGTGGCCATCCTGCTCGACCTGCAGGGCCCCAAGATCCGTACTGGCCGCTTCAAGGACGGC
GCGGTCGAGCTGAGCAAGGGCCAGGAGTTCACAATCACCACCGACACCGAGGTGCTCGGCGACGAGACCCAGGTGTCGAC
CACCTACCCGGGCCTGGTCGGCGACGTGAAGGTCGGCGATCAGATCCTGCTCGACGATGGGTATCTGGCGCTGGCGGTCA
CCGAGGTGCGCGACCACGCGGTCAAGACCGTGGTGGTCACCGGCGGCACGCTCAAGAACAACAAGGGCATCAACCTGCCC
CACGTCGAGGTGTCGGCGCCGGCGCTGAGCGAGAAGGATCGCGCCGACCTGGCGTTTGGCGTGCGCATGGGCGTGGACTA
CATCGCGCTGTCCTTCGTGCGCACGCCCGAGTGTGTGCGCGAGGCGCGGCGGCTGGCCACGGTCGAGGGCGACCATATCC
CGATCATCGCCAAGATCGAAAAGCCGCAGGCGCTCGACCGCATCGAGGCCATCGTGGACGAGGCCGACGGCGTGATGGTG
GCGCGCGGCGACCTGGGTGTGGAGCTGGGCCCGGAAAAAGTCCCGCTGGTCCAAAAAGAGCTCATCGAGCTGACCAACGC
CAAGGGCAAGGTGGTCATCACGGCCACGCAGATGCTCGAGTCGATGATTCAAAACCCCCGGCCGACCCGCGCCGAGGCCT
CGGACGTGGCCAACGCGGTGCTCGATGGCTCGGACGCGCTCATGCTCTCGGGTGAGACCGCGGCCGGCGATCATCCCACC
GAGGCGGTGCGCACCATGGCGCGCATCATCACCGAGGTCGAGCAGAGCGCCTACTACCGCCGGCAGCTCGAGCGGCCGGA
GCTGGCGCTGCAGGTGTCGGCCAACGCCATCGCCCACGGCGCCGCCATGGCCGCGCGCTCCATGCATTGCCGCATCATCG
TCACGGTCACCGAGTCGGGCGGCTCGGCGCGTCTGCTCAGCGAGTATCGCCCCGAGGCGCACGTCATCGCGCTGACCACC
AGCGAGACCACGTATCGCCGCCTGGCGCTGAACTGGGGCGTGACCCCGATCCTCACCAGCCCGGCCGCGACCATCAACGA
GGTCATCGAGTGCACCGAGACGGTGCTGCGCGAGCGCAACCTCGCCGGCGCGGGCGACCACGTGGTCATCACCGCGGCCA
TGCCCGTGGGCGCGGGCGAGACCACCAACATGCTCAAGCTGCACCGCATGCCCTGA

Protein sequence : 
MRRAKIVCTLGPASSTPERIGELIEAGMNVARLNFSHGDHEGHAKMLHTIRSEAERRGKPVAILLDLQGPKIRTGRFKDG
AVELSKGQEFTITTDTEVLGDETQVSTTYPGLVGDVKVGDQILLDDGYLALAVTEVRDHAVKTVVVTGGTLKNNKGINLP
HVEVSAPALSEKDRADLAFGVRMGVDYIALSFVRTPECVREARRLATVEGDHIPIIAKIEKPQALDRIEAIVDEADGVMV
ARGDLGVELGPEKVPLVQKELIELTNAKGKVVITATQMLESMIQNPRPTRAEASDVANAVLDGSDALMLSGETAAGDHPT
EAVRTMARIITEVEQSAYYRRQLERPELALQVSANAIAHGAAMAARSMHCRIIVTVTESGGSARLLSEYRPEAHVIALTT
SETTYRRLALNWGVTPILTSPAATINEVIECTETVLRERNLAGAGDHVVITAAMPVGAGETTNMLKLHRMP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-81 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-81 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-81 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-80 44
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 3e-59 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hoch_4428 YP_003268815.1 pyruvate kinase VFG0479 Protein 2e-81 44