Gene Information

Name : Hoch_3411 (Hoch_3411)
Accession : YP_003267806.1
Strain : Haliangium ochraceum DSM 14365
Genome accession: NC_013440
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4709562 - 4710749 bp
Length : 1188 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: scl:sce7598 cystathionine gamma-synthase

DNA sequence :
ATGCAAAAAAATGACAAGGGATTTGGAACGCTGTCGGTCCACGCGGGCGAGCCGCGGCGCAAGGCGCACGGGGCCATTAC
CACCCCGATAAGCTGCACGGCCACCTACGTCTTCGACGACACCGCCGAGATGCGCGACCACTTCGAGGGTCGCATCGACC
GCGAGGAATACGGCCGCTACGGCAACCCCACGGTGCGCATCGCCGAGCGCAAGCTGGCCGCGGTGTGCGGCAGCGAGGAC
TGCGTGATCTTCTCCAGCGGCATGGCCGCGATCACGTCCACCCTGCTGGCCATGTTGCGCTCGGGGCAGCACGTCATCCT
CACCTCGGATTGCTACCGCCGCACCCGCCAGTTCGTCACCCAGGTCCTGGGCCGCTTCGGCGTGGAGTCGACCATCGTCG
CGCCCGACGACTACGAGGGCCTGGCGGCCGCGATCCGGCCGCACGAGACCCGGCTCATCATCTCGGAGTCGCCGACCAAT
CCCTATCTGCGCTGCCTCGATCTCGAGCGCGTCAGCGAGATCAAGAACCAGCACCCGGGCGTCAAGCTGATCATCGACGC
CACCTTCGCCACGCCGGTCAATCAGCGGCCGCTCGAGCAGGGCGCTGACCTGGTGTTCCACTCGTGCACCAAGTACCTGG
GCGGACACAACGACATGCTCGGCGGCGCGGTGGTCGGCTCGGCGCCGCTGGTGCAGGCGCTGCGCGAGTTCCGCGGCGTG
CTCGGCGGCATCCTCGACGCCCACAGCGGCTATCTGCTGATCCGCGGCCTCAAGACCCTGCAGCTGCGCGTGGCCCGCCA
GAACCAGACCGCGATGGCGGTGGCGCGCGCGCTCGAGGCCCATCCCCATGTCGAGCGCGTGTACTACCCGGGCCTCGAGA
GCCACCCCGATCACGAGATCGCCAAGCGCCATATGCGCGGCTTCGGCGGCGTGGTCAGCTTTCTGGTCAAGGGCGATCTC
GACAGCACCTCGCGTTTCATCGACGCCTGCACCCTGCCCGTCATCGGCCCCTCGCTGGGTGGCGTGGAGAGCCTGATCGA
GCAGCCGGCGCTGATGTCGTTCTACGAGCTGAGCACCGAGCAGCGGCTGGCCATCGGCATCCGCGACAACCTGGTGCGGC
TCTCGGTCGGCGTCGAGGAGACCGAGGATCTCATCGCCGACCTCACCCAGGCGCTCGACGCGACCTGA

Protein sequence :
MQKNDKGFGTLSVHAGEPRRKAHGAITTPISCTATYVFDDTAEMRDHFEGRIDREEYGRYGNPTVRIAERKLAAVCGSED
CVIFSSGMAAITSTLLAMLRSGQHVILTSDCYRRTRQFVTQVLGRFGVESTIVAPDDYEGLAAAIRPHETRLIISESPTN
PYLRCLDLERVSEIKNQHPGVKLIIDATFATPVNQRPLEQGADLVFHSCTKYLGGHNDMLGGAVVGSAPLVQALREFRGV
LGGILDAHSGYLLIRGLKTLQLRVARQNQTAMAVARALEAHPHVERVYYPGLESHPDHEIAKRHMRGFGGVVSFLVKGDL
DSTSRFIDACTLPVIGPSLGGVESLIEQPALMSFYELSTEQRLAIGIRDNLVRLSVGVEETEDLIADLTQALDAT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-62 41
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-63 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hoch_3411 YP_003267806.1 cystathionine gamma-synthase BAC0207 Protein 4e-60 41