Gene Information

Name : Hneap_2372 (Hneap_2372)
Accession : YP_003264228.1
Strain : Halothiobacillus neapolitanus c2
Genome accession: NC_013422
Putative virulence/resistance : Virulence
Product : betaine aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 2537681 - 2539168 bp
Length : 1488 bp
Strand : -
Note : PFAM: aldehyde dehydrogenase; KEGG: rfr:Rfer_0356 aldehyde dehydrogenase

DNA sequence :
ATGAACACGATTGATTGGCATGCCCGGGCGGCGGCGCTCACAATTGACGGTCGCGCCTGGATCAACGGCCAACGCGTCGA
TGCCGCCGATGGCAACACGTTCGAATGTCTGTCGCCGGTGGATGGTCGCAAACTGGCGGAGGTGGCGCGCTGCAAGGCGG
CGGATGTCGACCAGGCTGTCGTCGCGGCGCGCGGCGCGTTCGAAGACCGGCGCTGGGCCGGTCTGTCGCCGCGGGAGCGC
AAGACGATCCTGATCCGTTTTGCCGATCTGGTGTTGGCAAACCGCGAAGAACTGGCGCTGCTGGAAACGCTGGATATGGG
CAAACCCATCTCGGCCAGCATGAGCACCGATGTGCCCGCTACGGCGAATACCCTGCGCTGGTACGGCGAAGCGATCGACA
AGGTCTACGACGAGATCGCGCCGACCAACGACCGCACCCTGGCGCTGATTACCCGCGAACCCATAGGCGTGGTCGCGGCC
ATCGTGCCGTGGAATTATCCCATGCTGATGGCTTCTTGGAAGATTGCACCGGCGCTGGCCGCCGGGAACAGCGTCATCCT
CAAGCCTTCGGAAAAATCGCCATTGACCGCGCTGCGTCTGGGCGAACTCGCTTTGGAAGCGGGTATTCCGGCGGGTGTGT
TGAATGTGGTGCCGGGCTTTGGCCCGGAGGCCGGTTCGCCGCTGGCTCTTCACAGGGATATCGACTGCATCGCCTTCACC
GGTTCGACCGCGGTGGGCAAGAAAATCCAGGTCATGGCGGGCGAGAGCAATCTCAAGCGCGCGTGGTGCGAGCTGGGGGG
CAAGTCGCCCAACATCGTCTTCGCCGACTGTCCCGATCTGGACCGTGCCGTGGCTGCTGCTGCCGGTTCGATCTTCTACA
ACCAGGGCGAAAGCTGCAACGCGCCGTCGCGCCTGCTGGTCGAGCGCTCCATCCGCGATGAATTCGTCGAGAAACTCAAG
CAGTACTCGCCCAAGCACATGCCGGGCGACCCGCTCGATCCCAACACGACGATGGGTGCGCTGGTCGACCAGATGCAGAT
GGATAACGTGCTCAAATACATCGAAGCGGGCAAAAGCCAAGGCGCGACCTTGTGCTGTGGTGGCGAGCGCGTCCGCACGG
AAACCGGCGGTTTCTATGTGTCGCCGACCATTTTCGACGGCGTGACCAACGAAATGATCATCGCCAGCGAAGAAATCTTC
GGCCCCGTGCTGTCGATCATCACCTTCGACTCGCAGGAAGAAGCGATCCGAATCGCCAACGACACCAGCTACGGCCTGGC
CGCCGCCGTCTGGACGCGGGATATTTCACGGGCGCATCTTGTGGCCCGTGCCCTGCGCGCCGGGACCGTGCACGTCAACT
GCTACGACGAAGACGACATCACCGTGCCGTTCGGCGGATTCAAGCAATCCGGCAACGGTCGCGACAAGTCGCTGCACGCG
CTCGAAAAATACACCGAACTCAAAACCACGTGGATCAGCCTCGCCTGA

Protein sequence :
MNTIDWHARAAALTIDGRAWINGQRVDAADGNTFECLSPVDGRKLAEVARCKAADVDQAVVAARGAFEDRRWAGLSPRER
KTILIRFADLVLANREELALLETLDMGKPISASMSTDVPATANTLRWYGEAIDKVYDEIAPTNDRTLALITREPIGVVAA
IVPWNYPMLMASWKIAPALAAGNSVILKPSEKSPLTALRLGELALEAGIPAGVLNVVPGFGPEAGSPLALHRDIDCIAFT
GSTAVGKKIQVMAGESNLKRAWCELGGKSPNIVFADCPDLDRAVAAAAGSIFYNQGESCNAPSRLLVERSIRDEFVEKLK
QYSPKHMPGDPLDPNTTMGALVDQMQMDNVLKYIEAGKSQGATLCCGGERVRTETGGFYVSPTIFDGVTNEMIIASEEIF
GPVLSIITFDSQEEAIRIANDTSYGLAAAVWTRDISRAHLVARALRAGTVHVNCYDEDDITVPFGGFKQSGNGRDKSLHA
LEKYTELKTTWISLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-127 62
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-76 44
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-78 44
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-78 44
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-78 44
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-77 44
hpaE AAO17179.1 HpaE Not tested tcd island Protein 4e-67 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hneap_2372 YP_003264228.1 betaine aldehyde dehydrogenase VFG0082 Protein 5e-77 44