Gene Information

Name : Hneap_0232 (Hneap_0232)
Accession : YP_003262142.1
Strain : Halothiobacillus neapolitanus c2
Genome accession: NC_013422
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 244073 - 245356 bp
Length : 1284 bp
Strand : +
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: bpt:Bpet4030 polysaccharide biosynthesis protein

DNA sequence :
GTGAAGAGCAAGGAAGCCGCTGAACCCATCATTGCTGTCATCGGCCTAGGCTATGTCGGCCTGCCGCTCGCGGTCGAGTT
CGGCAAAATACGCCCCGTGATCGGCTTTGATGTTGATGCCACCCGCATTGACCAATTAAAAAGCGGCCACGACCGCACGC
GCGAAGTCGAGCCGGATGAGCTGCAAAACGCCCGCCACCTGAGTTATACCGTCGATCCTGCCGATCTGCGAAAAGCCAGC
CTATTTATCGTCACCGTGCCCACGCCGATTGACGCGCACAAACGCCCGGACCTCAGCCCGCTGATCAAAGCCAGCGAAAC
CGTCGGGCGCGCGCTCAAACGCGGCGATATCGTGATTTATGAATCCACCGTCTACCCCGGCGCCACCGAAGAAGACTGCG
TGCCGGTGCTCGAACAATACTCCGGCCTGCGCTTCAACCACGATTTTTACTGCGGCTACAGCCCAGAGCGCATCAACCCC
GGCGACAAAACCCACCGCCTGCCCGCCATCAAAAAAGTCACCGCCGGTTCCACCCCTGCCGTGGCCGAAGCGGTCGATGC
GCTCTACCGGCAAATCATTACCGCCGGCACCCACCCAGCGCCCAGCATCCGCGTGGCCGAGGCCGCCAAGGTGATTGAAA
ACACCCAGCGCGATGTCAATATCGCGCTCATCAACGAACTGGCCATCTTATTCGGCAAACTCGGGCTCGATACCCAAGCC
GTGCTCGAAGCGGCGGGCAGCAAATGGAACTTCTTGCCGTTTCGCCCCGGCCTGGTAGGCGGCCACTGCATCGGCGTGGA
CCCGTACTACCTCACCCACAAAGCCCAGCAAGTCGGCCATCACCCTGAAATGATATTGGCCGGTCGCCGCATCAACGACG
GCATGGGCGCGTATGTGGCCGGCCAACTCATCAAAGCCATGCTGAAAAAAGGCATCACCGTACAAGGCGCGCGCGTACTC
GTGCTGGGGCTCACCTTTAAAGAAAACTGCCCCGATCTACGCAACACCCGCGTCATTGATGTGATTACCGAACTCAAAGA
CTACGGCCTAACCGTCGATGTGCACGACCCTTGGGCCGATGCCGCTTGCGCACGGCATGAGTACGGACTTGAGCTTACCG
CCACGCCACCATCAAATACCTATGAAGCCATCGTGCTGGCCGTTGCCCATCGAGAATTCAGAACCTTGGGCGCACCAGCC
ATTCACGCACTCGGCAAAGAACAGCATGTGCTCTACGACCTCAAACACCTCTTTCATGCCGATGAAGCCGACATTCGGTT
GTAA

Protein sequence :
MKSKEAAEPIIAVIGLGYVGLPLAVEFGKIRPVIGFDVDATRIDQLKSGHDRTREVEPDELQNARHLSYTVDPADLRKAS
LFIVTVPTPIDAHKRPDLSPLIKASETVGRALKRGDIVIYESTVYPGATEEDCVPVLEQYSGLRFNHDFYCGYSPERINP
GDKTHRLPAIKKVTAGSTPAVAEAVDALYRQIITAGTHPAPSIRVAEAAKVIENTQRDVNIALINELAILFGKLGLDTQA
VLEAAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKAQQVGHHPEMILAGRRINDGMGAYVAGQLIKAMLKKGITVQGARVL
VLGLTFKENCPDLRNTRVIDVITELKDYGLTVDVHDPWADAACARHEYGLELTATPPSNTYEAIVLAVAHREFRTLGAPA
IHALGKEQHVLYDLKHLFHADEADIRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 6e-137 64
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 6e-137 64
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-122 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hneap_0232 YP_003262142.1 nucleotide sugar dehydrogenase VFG0431 Protein 2e-137 64