Gene Information

Name : guaA (Pecwa_1269)
Accession : YP_003258689.1
Strain : Pectobacterium wasabiae WPP163
Genome accession: NC_013421
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1384151 - 1385728 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTGAAAACATTCATCAACACCGCATTCTTATTCTGGATTTCGGCTCGCAGTACACGCAACTGGTCGCACGTCGCGT
GCGCGAACTGGGCGTTTACTGTGAACTGTGGGCATGGGATGTCACGGAAGCGCAGATTCGCGGCTTTAATCCGAACGGGA
TCATCCTGTCCGGTGGCCCGGAAAGCACCACCGAGTTCGGCAGCCCGCGCGCGCCAGAATACGTTTTCAATGCTGGCGTA
CCGGTATTAGGCGTGTGCTACGGCATGCAGACGATGGCGATGCAGTTGGGTGGCCACGTTGAAGGTTCCAACGAGCGTGA
GTTTGGTTATGCGCAGGTAGAAATTAAGACGGATAGCGCTTTGGTGCGTGATATTCAGGATGCGTTGAGCGCCACGGGCG
CGCCGCTGCTGGATGTCTGGATGAGCCACGGCGACAAAGTGACGGCTATCCCAGAAGGGTTTGAGACCGTTGCCAGCACC
GATACCTGTCCGTTCGCTATCATGGCTAACGAAGAGAAGCGTTTTTACGGCGTGCAGTTCCACCCGGAAGTGACGCACAC
GCGTCAGGGTCAGCGCATGTTAGAGCGTTTTGTCCTTGATATCTGCCAGTGTGAGGCCCTGTGGACGCCGGCCAAGATTA
TCGACGATGCGGTGAACCGTATTCGTGAGCAGGTGGGTAACGACCATGTGATTTTGGGTCTGTCTGGCGGCGTGGATTCT
TCCGTTACCGCGATGCTGCTGCACCGTGCGATTGGCGATCGTCTGACCTGCGTGTTTGTTGATAACGGCCTGCTGCGTTT
GAACGAAGCCGATCAGGTTCTGGAAATGTTCGGCGATCATTTCGGTCTGAACATTGTGCATGTCGCGGCGGAAGATCGCT
TCCTGAATGAACTGGCTGGTGAAAACGATCCAGAAGCCAAACGTAAAATCATCGGTCGCGTGTTCGTTGAAGTGTTCGAT
GAAGAAGCCAACAAGCAAACCGACGTGAAATGGCTGGCGCAAGGCACCATCTACCCGGATGTAATCGAGTCTGCAGCGTC
TGCTACCGGTAAAGCACACGTGATCAAGTCACACCACAACGTGGGTGGACTGCCGAAAGAGATGAAGCTGGGTCTGGTTG
AGCCGCTGAAAGAGCTGTTCAAAGACGAAGTGCGCAAGATCGGTCTGGAACTAGGTCTGCCGTACAACATGCTGTTCCGC
CATCCGTTCCCTGGCCCAGGTTTGGGCGTGCGCGTACTGGGTGAAGTGAAGAAAGAATACTGTGACTTGCTGCGTCGTGC
GGATGCGATCTTCATCGAAGAGCTGCACAAAGCCGATTTGTACAACAAGGTTAGCCAGGCATTCACCGTCTTCCTGCCGG
TTCGCTCCGTGGGTGTGATGGGCGATGGTCGTAAATACGATTGGGTTGTCTCACTGCGTGCAGTCGAAACCATCGACTTT
ATGACCGCACATTGGGCACATCTGCCATACGACTTCCTTGGCCGCGTTTCCAACCGCATCATCAACGAAGTCGACGGCAT
CTCCCGCGTCGTTTATGACGTATCGGGCAAGCCACCGGCAACGATTGAGTGGGAATGA

Protein sequence :
MTENIHQHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRGFNPNGIILSGGPESTTEFGSPRAPEYVFNAGV
PVLGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEIKTDSALVRDIQDALSATGAPLLDVWMSHGDKVTAIPEGFETVAST
DTCPFAIMANEEKRFYGVQFHPEVTHTRQGQRMLERFVLDICQCEALWTPAKIIDDAVNRIREQVGNDHVILGLSGGVDS
SVTAMLLHRAIGDRLTCVFVDNGLLRLNEADQVLEMFGDHFGLNIVHVAAEDRFLNELAGENDPEAKRKIIGRVFVEVFD
EEANKQTDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYNMLFR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-129 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-129 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-129 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-111 48