Gene Information

Name : alr (D11S_0989)
Accession : YP_003255595.1
Strain : Aggregatibacter actinomycetemcomitans D11S-1
Genome accession: NC_013416
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : -
Position : 908584 - 909666 bp
Length : 1083 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCACATGAAGCCCGCGACAGCCAAAATCAGTTCTGTTGCTTTGAAGCACAATATTCAAACTATCAAACAAAAAGCTCC
GGAAAGCAAAATTATTGCGGTAGTCAAAGCCAACGCCTACGGCCATGGCGTCGTGTTCGTGTCTTCTGCCGTAGAAAATC
TGGTGGATTGCTTCGGCGTGGCGCGTTTGGAAGAAGCGTTAAAATTGCGTTCCAACGGTATTACCAAGCCGATTTTATTG
CTGGAAGGTTTTTTCTCTGCTAAAGATTTACCCGTTCTGGCGGTGAACAACATTCAAACCGTGGTGCACAGCCAAGAACA
GCTGGACGCGCTGGAACAGGCGAAAACCCCGAATCCGATCAAAGTCTGGTTAAAAATTGATACCGGTATGCACCGTTTAG
GGGTACATTTAGACGAAGTGGATGCCTTTTATCAAAAATTAAAATCGTTACCCTGTGTTGACCCGAATATCGGTTTTGTT
AGTCATTTTAGTCGCGCCGATGAATTGGCATGCGGTTATACCGAAAAACAATTGGCGCGTTTTTTACAGGCGACGGAAGG
TAAAGGCGGTGAGCGTAGTATTTCCGCATCCGGCGGTATTTTATTCTGGCAGGACGCGCATTTGGATTGGATCCGCCCTG
GTATTATTATGTACGGCATTTCACCGAATAATACCGCCGGCAAAGAATACGGTTTAATTCCGGTGATGAATCTTACGTCT
TCCCTAATTGCCGTACGCGAACATAAAAAAGGCGAGCCGGTGGGCTACGGCGGCGTTTGGATGAGTGACAAAGATACCAA
AATCGGCGTGGTGGCAATCGGCTACGGCGACGGTTATCCGCGTGACGTGCCGGAAGGTACGCCGGTTTACCTTAATGGTC
GACGTGTGCCTATTGTCGGAAAGGTTTCCATGGATATGCTTACCGTGGATCTTGGTGCAGACAGTCAGGATAAGGTCGGT
GATGAAGTGATCTTGTGGGGCAAAGAATTGCCTATTGAAGAAATTGCAGCAATTACCGGCGTTATCAGTTATGAATTAAT
CACCAAATTGACCCCGCGTGTTTTAACTGAATACATAGATTAA

Protein sequence :
MHMKPATAKISSVALKHNIQTIKQKAPESKIIAVVKANAYGHGVVFVSSAVENLVDCFGVARLEEALKLRSNGITKPILL
LEGFFSAKDLPVLAVNNIQTVVHSQEQLDALEQAKTPNPIKVWLKIDTGMHRLGVHLDEVDAFYQKLKSLPCVDPNIGFV
SHFSRADELACGYTEKQLARFLQATEGKGGERSISASGGILFWQDAHLDWIRPGIIMYGISPNNTAGKEYGLIPVMNLTS
SLIAVREHKKGEPVGYGGVWMSDKDTKIGVVAIGYGDGYPRDVPEGTPVYLNGRRVPIVGKVSMDMLTVDLGADSQDKVG
DEVILWGKELPIEEIAAITGVISYELITKLTPRVLTEYID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 1e-63 44