Gene Information

Name : D11S_0822 (D11S_0822)
Accession : YP_003255438.1
Strain : Aggregatibacter actinomycetemcomitans D11S-1
Genome accession: NC_013416
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 745159 - 747096 bp
Length : 1938 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGACTTTTTATAGCGGAAAAACCCAGTCTCGGACGCGCCATCGCCGATGTGTTGCCGAAACCGCATCAGCGCGGTGA
CGGTTTTATTAAATGCGGCGAGAACGACTGTGTCACTTGGTGCGTGGGGCATTTGCTGGAACAGGCGGAACCTGATGCGT
ACGACGCGCGTTTCAAACAATGGCGGCTGGAAGATTTGCCCATCGTGCCGCAAAAATGGCAACTCATTCCGAAAAAAGAA
ACCCACAAACAGCTGAAAACCGTTGAAAAATTAGTGCAGCAAGCGGATGTCTTGGTCAACGCCGGCGACCCCGATCGCGA
AGGGCAGTTGTTGGTGGACGAAGTGTTCAGTTATCTCAACCTGTCGGCGGAAAAACGCAATGCCATTCAACGCTGTTTAA
TCAGCGATTTGAACCCAAGTGCGGTAGAAAAAGCCATCAAAAAATTGCAGCCGAATCGTGATTTTGTCCCGCTTGCTACT
TCTGCCTTAGCCCGCGCCCGTGCCGATTGGTTATACGGCATTAACATGACCCGCGCCTATACTATTCACGGTCGGCAGGC
GGGCTACGACGGCGTGCTTTCCGTCGGGCGCGTACAAACACCGGTGCTTGGTTTAATCGTGCGCCGTGATTTGGAAATCG
AACATTTTCAGCCGAAAGATTTTTTTGAAGTGCTGGCTTGGGTGCGGGATCCGAAAGGTGAAAAAACACCTGAAAAACCG
ACCGCACTTTTTTCCGCGTTATGGCAACCGAGCAAAGCCTGCGAAGATTATCAGGACGATGACGGACGCGTGTTATCCCG
CGCGCTGACGGAAAATGTGGTAAAACGCATTGCCGACCAACCGGCGGAAGTCACCGATTACACGGACAAACGAGAGAAAG
AAACGGCGCCTTTGCCTTATTCGTTATCCGCCCTGCAAATTGATGCCGCCAAGCGTTTTGGGATGTCGGCGCAGGAGGTG
CTGGACACGTGTCAGCGCTTGTATGAAACCTACAAATTGATTACTTATCCCCGTTCCGATTGTCGCTATTTACCACAAGA
GCATTTTGCCGACCGAATGGCGGTGATGAATGCGATTTCCAGTCATTTATCCCAATTTCAGCCGTTGCCGGAAATCATCG
ATCCCGAGCAGAAAAATCGTTGCTGGAACGATAAAAAAGTGGAGGCGCACCACGCCATTATTCCCACGGCAAAAAATCGC
CCGGTAGGTTTGACTTCGGCAGAACAAAATGTGTATTTTCTGATTGCCCGCCAATACCTCATGCAATTTTGTCCTGATGC
GGAATACCGCAAATGTAAAATCACCTTAAATATCGCCGGCGGAACCTTTGTGGCGCAGGCGCGCAATTTGCAAATTGCCG
GCTGGAAGCAACTTTGGGGCAAAGAGGACAGCGACGATGAACAGCAGGACGCGCTGCTGCCCGTGGTAAAAAAAGGGCAA
ATACTGCATTGCGAAAAGGGCGAGATTGTCAGTAAAAAAACGCAGCCGCCGAAACCCTTCACCGACGCGACTTTGCTTTC
CGCCATGACAGGCATTGCCCGCTTCGTGCAGGATAAAGAATTGAAAAAAATCCTACGTGAAACCGACGGCTTGGGCACTG
AAGCCACCCGTGCGGGCATCATCGAGTTGTTGTTTAAACGCGGTTTTCTGTATAAAAAAGGACGCAATATTCACAGCACC
GAAGCAGGGAGGATTCTGATTAACGCCTTGCCTGATGTGGCAACCCAGCCCGATATGACCGCACATTGGGAATCCCAGTT
GGACGGTATTAGCCGCAAACAGGCGAGTTATCAGCAATTTATGGAAAACCTGACGCAACTTTTGCCGGAATTGTTGCATT
ACATTAATTTTTCCGCCTTGCGTGAGTTAAGTCGGCATAATTCGGGTGTCAAAAAGCAGGGCATTAAAAAGAAAACATCG
AGAATCACGAAAAGTTAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHQRGDGFIKCGENDCVTWCVGHLLEQAEPDAYDARFKQWRLEDLPIVPQKWQLIPKKE
THKQLKTVEKLVQQADVLVNAGDPDREGQLLVDEVFSYLNLSAEKRNAIQRCLISDLNPSAVEKAIKKLQPNRDFVPLAT
SALARARADWLYGINMTRAYTIHGRQAGYDGVLSVGRVQTPVLGLIVRRDLEIEHFQPKDFFEVLAWVRDPKGEKTPEKP
TALFSALWQPSKACEDYQDDDGRVLSRALTENVVKRIADQPAEVTDYTDKREKETAPLPYSLSALQIDAAKRFGMSAQEV
LDTCQRLYETYKLITYPRSDCRYLPQEHFADRMAVMNAISSHLSQFQPLPEIIDPEQKNRCWNDKKVEAHHAIIPTAKNR
PVGLTSAEQNVYFLIARQYLMQFCPDAEYRKCKITLNIAGGTFVAQARNLQIAGWKQLWGKEDSDDEQQDALLPVVKKGQ
ILHCEKGEIVSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLYKKGRNIHST
EAGRILINALPDVATQPDMTAHWESQLDGISRKQASYQQFMENLTQLLPELLHYINFSALRELSRHNSGVKKQGIKKKTS
RITKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 6e-106 42
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-101 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-107 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-107 41
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-107 41