Gene Information

Name : murD (D11S_0784)
Accession : YP_003255400.1
Strain : Aggregatibacter actinomycetemcomitans D11S-1
Genome accession: NC_013416
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 708759 - 710063 bp
Length : 1305 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGCAATATCAAGATAAAAAAGTCACGGTAATCGGGTTAGGCAAAACAGGCTTATCCTGTGTGGATTTTCTGCGTGCCAA
ACAGGCGGATGTGCGTGTCATAGATACGCGTCAACATCCTGCGGGCGCTGAGCAGCTTGATAAAGCGATTCCTCTGCATA
CGGGCGGTTTAAACCAGCAATGGCTGCTGGAAAGCGATCTGATTGTTATCAGCCCGGGGCTGGCGGTAAAAACACCTGAA
ATTCAGACCGCACTTCAAGCAGGTGTCGAGGTGGTGGGCGACATCGAATTATTCTGTCGCGAGGCGGATAAACCGATTGT
GGCAATTACCGGTTCCAACGGTAAAAGCACTGTCACCACATTGGTGGCGGAAATGGCGAAGGCCGCCGGTTTAAGAGTGG
GTATGGGCGGCAATATTGGTATTCCGGCACTTTCCCTGTTAAATCAACAACATGATTTGTATGTGTTGGAACTGTCCAGC
TTCCAATTGGAAACAACCTATTCCCTCAAGGCTGTGGCGGCAACAGTATTAAACGTGACCGAAGATCACATGAATCGCTA
TGTGGATCTGCAGGATTATCGCCACGCGAAATTAAACATTTACAATCATTGCCAAACGGCGGTGATTAATGCGGAAGATG
CATTGACGTTGCCAACGACCCAGCGACCGCAAAAGCAGGTTTCTTTTGGTGAAAACCACGCGGATTATTGGTTAAAAACC
GAAAATAACAAAACCTATTTAATGGCGTACGATGAAGCGGTGTTAGCCTGTGATGAAATGAAATTGACCGGTCGCCATAA
TTACATGAATGCCTTGGCTGCCATTGCGTTGGCACAGGCGGCAGGCATAAATTTAACCGGAATTCGAACCGCACTTTGTG
CGTTCGGTGGTTTGGAGCACCGCTTCCAAGTGGCGCATATCGCTGACGGCGTGCGCTGGATTAACGATTCCAAAGCCACT
AATGTGGGTAGCACCGTTGCCGCCTTAACCGGTTTGCAGGTAGCGGGCAAGCTCCATTTATTGCTCGGCGGTGACGGCAA
AGGCGCGGATTTCTCCGAATTGGCACGCTTAATTAATCAACCGCACATTTACTGCTATTGTTTCGGTCGCGACGGCAAAC
AGTTAGCCGCACTCTCTTCCCAAAGCCAATTATTTGACACCATGGAACACGCCATTGCGGCGATTCGTCCGCAGCTACAG
GCAGGCGACATGGTGCTGTTATCACCGGCTTGCGCCAGTTTGGATCAATTCAGCTGTTTTGAAGCTCGCGGCGATGAATT
TACGCGTTTGTCACGCTTAAGTTAA

Protein sequence :
MQYQDKKVTVIGLGKTGLSCVDFLRAKQADVRVIDTRQHPAGAEQLDKAIPLHTGGLNQQWLLESDLIVISPGLAVKTPE
IQTALQAGVEVVGDIELFCREADKPIVAITGSNGKSTVTTLVAEMAKAAGLRVGMGGNIGIPALSLLNQQHDLYVLELSS
FQLETTYSLKAVAATVLNVTEDHMNRYVDLQDYRHAKLNIYNHCQTAVINAEDALTLPTTQRPQKQVSFGENHADYWLKT
ENNKTYLMAYDEAVLACDEMKLTGRHNYMNALAAIALAQAAGINLTGIRTALCAFGGLEHRFQVAHIADGVRWINDSKAT
NVGSTVAALTGLQVAGKLHLLLGGDGKGADFSELARLINQPHIYCYCFGRDGKQLAALSSQSQLFDTMEHAIAAIRPQLQ
AGDMVLLSPACASLDQFSCFEARGDEFTRLSRLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 8e-54 41
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 8e-54 41