Gene Information

Name : hemC (D11S_0695)
Accession : YP_003255316.1
Strain : Aggregatibacter actinomycetemcomitans D11S-1
Genome accession: NC_013416
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 626122 - 627048 bp
Length : 927 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGACGCAAAAAAGCTTAAAAATAGCCACCCGCCAAAGTCCCTTGGCATTATGGCAGGCGAATTATGTGAAAGACCTCTT
GCAGCAGTTATATCCTGATCTGAATGTGGAACTCGTCCCAATGGTCACCAAAGGCGATGTGATTTTGGATTCGCCGTTGG
CGAAAATCGGCGGCAAAGGTTTGTTTGTCAAAGAACTGGAAAATGCGCTGCTGAATAAAGAGGCGGATATTGCCGTGCAT
TCCATGAAAGATGTGCCCATGCAATTTCCCGAAGGGCTTGGGTTGGCGGTGATTTGCAAACGTGAAGATCCGCGTGATGC
ATTCGTCTCAAATTCTTACCGCACTTTAGCGGAATTACCGCAAGGTGCCGTGGTCGGCACTTCCAGTTTACGCCGTCAAT
GTCAGTTAAAAACATTACGTCCCGATTTGGAAATTCGTTCTTTGCGCGGCAATGTGGGTACGCGTTTGAGTAAATTAGAT
AACGGTGATTATGATGCCATTATTTTGGCTTCCGCCGGTTTGATTCGGTTAGGTTTAGCAGAGCGTATCGCTTCTTTTAT
TGATGTGGAGCAATCCTTGCCTGCTGCCGGACAAGGCGCGGTGGGCATCGAATGTCGGACAGACGATGTTGCGGTTCAAC
AATTACTGGCGCCACTGGCGGATGCGGAAACTACCTCTTGCGTGCTGGCGGAACGCGCCATGAACCATCACTTACAAGGC
GGTTGCCAAGTGCCTATCGGCGGTTATGCGGTGTTGCGTGATAGTGAATTGTATTTGCGCGCCTTGGTAGGCAGTGTGGA
CGGTTCGACGATTATTCGCGCGGAAGGCAAAAGTGCGGTGGAAAACGCCGATGTTTTAGGCGTGCAAATTGCCGAACAGC
TACTGGCGCAGGGGGCGGATAAAATTTTGCAGGACATTTACGCGTAA

Protein sequence :
MTQKSLKIATRQSPLALWQANYVKDLLQQLYPDLNVELVPMVTKGDVILDSPLAKIGGKGLFVKELENALLNKEADIAVH
SMKDVPMQFPEGLGLAVICKREDPRDAFVSNSYRTLAELPQGAVVGTSSLRRQCQLKTLRPDLEIRSLRGNVGTRLSKLD
NGDYDAIILASAGLIRLGLAERIASFIDVEQSLPAAGQGAVGIECRTDDVAVQQLLAPLADAETTSCVLAERAMNHHLQG
GCQVPIGGYAVLRDSELYLRALVGSVDGSTIIRAEGKSAVENADVLGVQIAEQLLAQGADKILQDIYA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-88 66
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-88 66