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Name : leuS (D11S_0466) Accession : YP_003255095.1 Strain : Aggregatibacter actinomycetemcomitans D11S-1 Genome accession: NC_013416 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 425224 - 427812 bp Length : 2589 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAGCAATATCGTCCTGATTTGCTTGAACCGGAAGTGCAAAAATTCTGGCAGGACAATAAAACTTTCAAAGCAGT ACAAGATAACAACAAAGAAAAATATTACTGTCTTTCCATGCTGCCGTATCCGTCCGGTCGTTTGCACATGGGGCATGTAC GCAATTACACCATCGGCGATGTGGTGTCCCGTTATCAACGTATGATTGGCAAGAACGTGTTGCAGCCGATGGGCTGGGAT GCCTTCGGTTTGCCGGCGGAAGGCGCGGCGGTGAAGAATAATACCGCTCCGGCGAAATGGACTTACGAAAATATTGCCTA CATGAAAAACCAGTTGCAACTGTTGGGTTTCAGTTACGATTGGGATCGCGAAGTAACCACGTGCCGCCCGGAATATTACA AATGGGAGCAATGGTTCTTTACCGAGCTATATAAAAAAGGCTTGGTGTATAAAAAAACCTCTACCGTGAACTGGTGTCCG AACGATAAAACCGTGTTGGCGAACGAGCAGGTGCATGAAGGTTGTTGCTGGCGTTGTGATACGCCGGTGGAGCAAAAAGA GATTCCGCAATGGTTTATCAAAATCACCGATTACGCCGAGCAGTTGCTTAATTGCTTAGATGAGTTACCACAATGGCCGG AAACGGTGAAAACCATGCAACGCAACTGGATCGGGCGTTCCGAGGGGGTGGAAATCACCTTTGACATTAAAGATACCAAC GAGAAGCTCGCGGTTTATACCACCCGCCCTGACACTTTCTATGGCGTCAGCTATGTGGCGGTGGCAGCGGCCCATCCGTT AGCCACGCTGGCGGCGCAGAATAATCCGGCATTGGCGCAATTCATTCAGGAAGCGAAAAATACCAAAGTTGCCGAGGCAG ACATTGCCACTATGGAGAAAAAAGGCATGGCGACCGGTTTGTATGCGGTGCACCCGCTAACCGGCGAATTGTTGCCGGTG TGGGTGGCGAATTTTGTCTTAATGCACTATGGTACCGGCGCGGTCATGGCGGTGCCGGCGCACGATCAGCGCGACTATGA ATTCGCACAAAAATACGGTTTACCGATTAAACAGGTTATTGAACCGATTCATGGCGAAGAAATCGATTTAACCAAACAAG CCTTTACCGAACACGGCAAACTCATTCATTCCGCCGAATTTGACGGTTTGGAATTTGGCGCGGCGTTCAGCGGCATTGCC GATAAATTGGAACAGTTAGGCATGGGTAAACGCCAAGTGAACTACCGCCTGCGCGACTGGGGCGTGTCCCGTCAGCGTTA TTGGGGCGCACCGATTCCGATGCTGACCTTGGAAAATGGCGATGTGGTGCCGGCACCAATGAAAGATTTGCCGATTATCC TACCGGAAGATGTAGTGATGAACGGTGTGAACAGCCCGATTAAAGCGGATCCCGAATGGGCGAAAACCACCTATCAGGGC AAACTGGCGTTGAAAGAAACGGACACCTTTGACACCTTCATGGAATCTTCCTGGTATTACGCCCGTTACACCTGCCCGGA ATATCAACAAGGTATGCTGAATAGCGAAGAAGCTAATTACTGGTTGCCGGTAGATCAATATATCGGCGGTATCGAACATG CCACCATGCACTTATTATATTTCCGGTTCTTCCATAAATTGCTGCGTGATGCCGGCTTTGTCACCAGCGATGAACCGGCG AACAAGTTGTTGTGTCAAGGCATGGTGTTGGCGGACGCGTTCTATTACACCAGCCCGACCAATGAGCGTATCTGGGTTTC ACCGACCAACGTTACATTAGAACGTGATGACAAAGGGCGTATTGTCAAAGCGACGGATGACGAAGGACATGAACTGGTAC ATGCCGGTATGACCAAAATGTCGAAATCCAAAAACAACGGTATCGACCCGCAGGAAATGGTGGAAAAATACGGCGCGGAC ACCGTGCGTTTGTTCATGATGTTCGCCTCCCCAGCAGAAATGACTTTAGAATGGCAGGAGTCCGGCGTGGAAGGCGCGAA ACGTTTCTTGGCGCGTTTGTGGAATTTGGTGTTTGAATACAACAAAAATCCGGCAAAAACGCCGTTAAATCCGACCGTAC TTTCCGCCGCCCAAAAGGCTCTGCGTCGTGACGTACACAAAACCATCGCGAAAGTGAGCGATGACATCGGTCGTCGTCAA ACCTTCAATACCGCTATTGCGGCGATTATGGAGTTGATGAACAAACTCACCCGCGCGCCGTTGGACGACGAACAAGATCG CGCCATGATGGCGGAGGCCTTGAGCGCGGTGGTTCGTATGCTTTACCCGATTACCCCGCACATTTGCTTCCATTTATGGC AAGAACTCGGCAATCAGGACATTATTGATTTCGCCCCTTGGGTGGAAGCCGATGCCGAAGCGATGATTGAAGATGAAAAA CTCATCGTAGTGCAAGTGAACGGTAAAGTGCGCGGCAAAGTAACCGTGGCGGCGGATACCGATGAAGACAGGGTGAAAGC GGTTGCCTTTGCCGATGAAAATGTCAAACGCTTTACCGACGGAATGCAAATTGTGAAAGTGATTTACGTTGCCGGCAAAT TACTCAACGTGGTGGTGAAACCACAATAA Protein sequence : MQEQYRPDLLEPEVQKFWQDNKTFKAVQDNNKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVSRYQRMIGKNVLQPMGWD AFGLPAEGAAVKNNTAPAKWTYENIAYMKNQLQLLGFSYDWDREVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP NDKTVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLNCLDELPQWPETVKTMQRNWIGRSEGVEITFDIKDTN EKLAVYTTRPDTFYGVSYVAVAAAHPLATLAAQNNPALAQFIQEAKNTKVAEADIATMEKKGMATGLYAVHPLTGELLPV WVANFVLMHYGTGAVMAVPAHDQRDYEFAQKYGLPIKQVIEPIHGEEIDLTKQAFTEHGKLIHSAEFDGLEFGAAFSGIA DKLEQLGMGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVPAPMKDLPIILPEDVVMNGVNSPIKADPEWAKTTYQG KLALKETDTFDTFMESSWYYARYTCPEYQQGMLNSEEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSDEPA NKLLCQGMVLADAFYYTSPTNERIWVSPTNVTLERDDKGRIVKATDDEGHELVHAGMTKMSKSKNNGIDPQEMVEKYGAD TVRLFMMFASPAEMTLEWQESGVEGAKRFLARLWNLVFEYNKNPAKTPLNPTVLSAAQKALRRDVHKTIAKVSDDIGRRQ TFNTAIAAIMELMNKLTRAPLDDEQDRAMMAEALSAVVRMLYPITPHICFHLWQELGNQDIIDFAPWVEADAEAMIEDEK LIVVQVNGKVRGKVTVAADTDEDRVKAVAFADENVKRFTDGMQIVKVIYVAGKLLNVVVKPQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 9e-154 | 42 |
