Gene Information

Name : D11S_1900 (D11S_1900)
Accession : YP_003256476.1
Strain : Aggregatibacter actinomycetemcomitans D11S-1
Genome accession: NC_013416
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1832203 - 1833333 bp
Length : 1131 bp
Strand : -
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGTTGTTTCGCGGAGGATTTATGACACAAAAATATGCGATTGATACCCTATTAGCCCAAGCCGGCAATCGCACCGACGA
GCGCACCGGCGCCGTTTCCACCCCAATTTTCCTTTCTACCGCTTACGGGCACCATGGCATTGGTGAAAGTACCGGTTTTG
ATTATACCCGAACCAAAAATCCTACTCGCGCTGTGTTAGAAGAGACTATCGCCCAATTAGAAAAGGGCGAGCGCGGTTTT
GCCTGCTCTTCCGGCATGGCGGCAATTCAATTATTGATGTCATTATTTACGTCACCCGATGAGTGGATTGTATCCAGTGA
TGTTTATGGTGGAACTTATCGTTTATTGGATTTTTGTTACAAAAACACCAACGGCGTCAAACCGGTTTATGTGAATACCG
CTTCTGTTCAGGCGATTGAAGGGGCGATTACGTCGAACACCAAAGCAGTTTTTATTGAAACTCCCTCCAATCCGTTAATG
GAAGAATGCGATGTGGATGCCATTGCCAAGGTGGCGAAAAAGCACAATTTATTACTTATTGTCGATAATACGTTCCTCAC
GCCGGTGTTATTCCGCCCGATGGAACATGGGGCTGATATTGTGATTCATAGCGGGACCAAATATATTGCCGGGCATAATG
ACGTTTTAGTCGGTTTGATTGTTGCTAAAGGGCAAGAACTGTGTGATCGCCTGTTTTACATCCAAAACGGTGCGGGCCCG
GTGTTATCGCCGTTTGACTCCTGGTTAACCATTCGCGGTATGAAAACTTTGGCATTGCGTATGCAGCGTCATGAAGAAAA
TGCCAAAGCCATCGCCGAATTTTTGCGTCAACAACCGCAAGTGAAAGATGTGTTGTATCCTAATAAAGGCGGTATGTTAT
CTTTCCGCCTGCAGGATGAAAGTTGGGTTAATACGTTCTTGAAGGCGATTAAATTGATTACGTTCGCCGAAAGCCTTGGC
GGTACCGAAAGTTTCATTACTTACCCGGCAACTCAAACCCACATGGATATTCCGGAAGCAGAGCGCATTGCGCGCGGTAT
CACCAATAATCTGCTGCGTTTCTCTGTCGGTTTGGAAAATGTGGAAGACATCAAAGCGGATCTGGTACAGGCGTTTGCAC
AGCTTAAATAA

Protein sequence :
MLFRGGFMTQKYAIDTLLAQAGNRTDERTGAVSTPIFLSTAYGHHGIGESTGFDYTRTKNPTRAVLEETIAQLEKGERGF
ACSSGMAAIQLLMSLFTSPDEWIVSSDVYGGTYRLLDFCYKNTNGVKPVYVNTASVQAIEGAITSNTKAVFIETPSNPLM
EECDVDAIAKVAKKHNLLLIVDNTFLTPVLFRPMEHGADIVIHSGTKYIAGHNDVLVGLIVAKGQELCDRLFYIQNGAGP
VLSPFDSWLTIRGMKTLALRMQRHEENAKAIAEFLRQQPQVKDVLYPNKGGMLSFRLQDESWVNTFLKAIKLITFAESLG
GTESFITYPATQTHMDIPEAERIARGITNNLLRFSVGLENVEDIKADLVQAFAQLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-65 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-66 42