Gene Information

Name : D11S_1817 (D11S_1817)
Accession : YP_003256397.1
Strain : Aggregatibacter actinomycetemcomitans D11S-1
Genome accession: NC_013416
Putative virulence/resistance : Virulence
Product : hemolysin D
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1566
EC number : -
Position : 1753967 - 1755400 bp
Length : 1434 bp
Strand : -
Note : identified by Glimmer3; putative

DNA sequence :
ATGAAAACTTGGCTTTTGGCATTGTATGATGTGCTTTCCCGTTATAAAAACGTGTGGAATGAAACTTGGAAAATTCGTAA
ACAGCTTGATTCTCCGGTTAGAGAAAAAGATGAAAATGAATTTCTGCCCGCGCATTTGGAATTAATTGAAACACCTGTAT
CAAATGCACCACGATTCGTGTCTTATTCCATTATGCTCTTTTTAACTTTAGCGATTATTGTTTCTATTTTTAGCAATGTG
GAAATTATCGCAACGGCTTCAGGAAAATTCGCACTAAGCGGGAGAAGCAAAGAAATTAAACCGATTGAAAACTCATTGGT
TAAAGATATTTTTGTGAAAGAGGGCGAATACGTGAAAAAGGGTGAACTATTGTTAAAACTGACCGCACTTGGTGCCGAAG
CGGATACGTTAAAAACGAAGACATCGCTTTCTCAGGCTAAACTGGAGGAATTTCGTTATAAATCTTTATTGGAAGCTGTT
GAAAAAGATCAATTACCAATATTAGATTTTTCTAAAATTGATTTGCCTTTTATGACGGAAAACGATCAAAAAAGAGTGAC
TTTACTGATTGAAGAACAATTCTCTACTTGGCAAAAACAACGCCATCAGAAAACCTTGAATCTTAATAAAAAAGAAGCGG
AAAAACTCAGTTATTTGGCACGAATAAAAAAATATGAAGGTCTGATTAATACAGAGCAAGTCCGATTGGATGATTTTAGA
GCCTTATATAAGGAACATGCTATTGCAAAACATACAGTTTTAGATGAAGAGAATAAATATCAGGATGCAATCAATGAGCT
TGAGGTATATAAGGCGAGTTTAATGCAAGTTGAAAACGAAGTTTTATTGGCCAAGGAAGAGCAGGAATTAGTCACACAAT
TGTTCAAAAATGATATTTTAGACAAGCTAAAACAGGCGACGGATAATGTGAATTTATTGACATTCGAACTAGACAAAAAC
AATCAACGCCAGCAAGTCTCTGAAATTCGAGCTCCTGTATCAGGTACTGTACAACAATTAAAAGTTCACACAATAGATGG
CGTTGTTACTACGGCTGAAACATTAATGGTAGTTGTGCCGGAAGAAGATTCCCTTGAAGTCACCGCACTTATTCAAAATA
AAGATATTGGTTTTGTGAAAGAAGGGCAAGAGGTTGTAATTAAGGTCGAAGCCTTCCCCTATACCCGTTATGGTTATTTA
ACGGGAAAAGTGAAAAATATTACTTTAGATGCGATTGAACATCCAAAGCTTGGACTTGTATTTAATACGATTATTGAACT
GGATAAAAAAACACTTTCTGCCGAAGAAAAAGAAATCCCACTTTCCGCAGGGATGGAAATTACTGCAGAAATTAAGACAG
GCATGAGAAGCGTTATAAGCTATCTACTTAGCCCATTAGAAGAATCTATTGATAAAAGTTTAAGAGAACGTTAA

Protein sequence :
MKTWLLALYDVLSRYKNVWNETWKIRKQLDSPVREKDENEFLPAHLELIETPVSNAPRFVSYSIMLFLTLAIIVSIFSNV
EIIATASGKFALSGRSKEIKPIENSLVKDIFVKEGEYVKKGELLLKLTALGAEADTLKTKTSLSQAKLEEFRYKSLLEAV
EKDQLPILDFSKIDLPFMTENDQKRVTLLIEEQFSTWQKQRHQKTLNLNKKEAEKLSYLARIKKYEGLINTEQVRLDDFR
ALYKEHAIAKHTVLDEENKYQDAINELEVYKASLMQVENEVLLAKEEQELVTQLFKNDILDKLKQATDNVNLLTFELDKN
NQRQQVSEIRAPVSGTVQQLKVHTIDGVVTTAETLMVVVPEEDSLEVTALIQNKDIGFVKEGQEVVIKVEAFPYTRYGYL
TGKVKNITLDAIEHPKLGLVFNTIIELDKKTLSAEEKEIPLSAGMEITAEIKTGMRSVISYLLSPLEESIDKSLRER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 3e-156 68
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 2e-156 68
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 4e-156 68
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 2e-141 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
D11S_1817 YP_003256397.1 hemolysin D VFG0908 Protein 8e-157 68
D11S_1817 YP_003256397.1 hemolysin D VFG1502 Protein 2e-156 68
D11S_1817 YP_003256397.1 hemolysin D VFG1556 Protein 2e-156 68
D11S_1817 YP_003256397.1 hemolysin D VFG0843 Protein 5e-119 53