Gene Information

Name : D11S_1582 (D11S_1582)
Accession : YP_003256166.1
Strain : Aggregatibacter actinomycetemcomitans D11S-1
Genome accession: NC_013416
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : -
Position : 1507060 - 1507947 bp
Length : 888 bp
Strand : -
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGATGCGTTGCTTAGCCTTAGATATCGGCGGAACCAAAATTGCCGCCGCCATTGTTGCTCAGAACCAAGTCACACAACG
GAAACAAATCCATACGCCACAGGAAAATGTGGTGGAAGCCATGCATCAGACTCTCGCGCAATTACTCAAGGATTATGCGG
GGCAATTTGATTATGTTGCGGTTGCATCAACGGGCATCATCAATAAAGGAATATTGACCGCATTGAATCCGAAAAATTTG
GGGGGACTTGCCTACTTCCCGTTAAAAGAAAGCCTTTCCAAGCATACGTCCAATCCGGTGTATTTATTAAATGATGCACA
GGCGGCGACTTATGCGGAATATCAACTGCAAGATAAAAATAACATTCAAAACTTTGCTTTTATTACCGTCTCCACCGGTG
TGGGAGGTGGGTTAATTTTAAATCGCCAATTACTTACCGAACCGAACGGCATTGCCGGTCATATCGGACACACCGTCGCG
GATCCGAACGGGCCTGTGTGCGGTTGCGGACGCGTGGGCTGTGTGGAAGCCATTGCGTCAGGGCGTGCCATTGAAGCAGT
TTCCAAACAATGGGACGATCCTTGCGAACCGAAAGAGGTGTTCGCCCGTTTTCGAAAAACGGACGAAAAAGCTACCGCAC
TTGTGTCCCTTTCGGCAAAAGCCATCGCCAATCTGGTGGCGGATTTGGTTATTGGTATGGATATTCAAAAAGTGGTTATC
GGCGGCAGCGTAGGACTGGCGGAAGGCTATTTGCCCCTGGTACAAGCCTATTTGCAACAAATGCCGGAAGTGTATCGCGG
CGCTATCGAATCGGCTCAACTAGGGCAAGATGCGGGGCTTATCGGTGCAGCTTCTTGGGCGCTGGCGCAAATTCAGGCTG
CCGCGTAA

Protein sequence : 
MMRCLALDIGGTKIAAAIVAQNQVTQRKQIHTPQENVVEAMHQTLAQLLKDYAGQFDYVAVASTGIINKGILTALNPKNL
GGLAYFPLKESLSKHTSNPVYLLNDAQAATYAEYQLQDKNNIQNFAFITVSTGVGGGLILNRQLLTEPNGIAGHIGHTVA
DPNGPVCGCGRVGCVEAIASGRAIEAVSKQWDDPCEPKEVFARFRKTDEKATALVSLSAKAIANLVADLVIGMDIQKVVI
GGSVGLAEGYLPLVQAYLQQMPEVYRGAIESAQLGQDAGLIGAASWALAQIQAAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 1e-32 46
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 8e-28 41
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 8e-28 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
D11S_1582 YP_003256166.1 N-acetylmannosamine kinase VFG1115 Protein 3e-28 41