Gene Information

Name : D11S_1562 (D11S_1562)
Accession : YP_003256146.1
Strain : Aggregatibacter actinomycetemcomitans D11S-1
Genome accession: NC_013416
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 1485511 - 1486182 bp
Length : 672 bp
Strand : +
Note : identified by Glimmer3; putative

DNA sequence : 
ATGGCTAAAACCGTGATTGAAACACAGCATTTATATAAAAGATTCGGGCAAGTGACCGCACTTGAAGACATTAATATTCA
AATTGCCGAAGGGGAATTTGTTGCCATCATGGGCGCTTCCGGCTCGGGGAAAACCACCTTAATGAACATTCTCACCGGCT
TGGACACCGCCAGCGAAGGCAAAGTGATTTTAGACGGCGTAGATGCGGCGCAACTGGACGAAACGGGCAGGCAACGCTTC
CGTGCGGAGAAAATCGGCTTGGTGTTCCAACAATTCCATTTAATTCCCTATTTAACCGCGTTGGAAAACGTGATGTTGGC
GCAACATTATCACAGCGTGGTGGATGAAGCCGCCGCCAAAGCGGTGCTGGAACAGGTGGGGTTGGCACATCGAATGGATC
ACCGCCCTAGCCAACTTTCCGGCGGGGAACAGCAACGGGTGTGTATCGCCCGCGCATTGGTCAATCAACCGCCGGTGATT
TTTGCCGACGAACCGACAGGCAACCTCGACGAGAAAAATGAACATTTGGTGCTGGATTTGCTCACCGAGTTAAACCGACA
AGGACGCACGATCGTAATGGTGACCCACAACCCCGATTTAGGCAAACTCACCAATCGCATTCTTTATTTACAACACGGCA
AACTGTTAAGCGAGGAACAAAATGTGGGCTAA

Protein sequence : 
MAKTVIETQHLYKRFGQVTALEDINIQIAEGEFVAIMGASGSGKTTLMNILTGLDTASEGKVILDGVDAAQLDETGRQRF
RAEKIGLVFQQFHLIPYLTALENVMLAQHYHSVVDEAAAKAVLEQVGLAHRMDHRPSQLSGGEQQRVCIARALVNQPPVI
FADEPTGNLDEKNEHLVLDLLTELNRQGRTIVMVTHNPDLGKLTNRILYLQHGKLLSEEQNVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 3e-28 41
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-29 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 1e-29 41
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-29 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
D11S_1562 YP_003256146.1 macrolide export ATP-binding/permease MacB NC_008702.1.4606598. Protein 3e-34 45
D11S_1562 YP_003256146.1 macrolide export ATP-binding/permease MacB NC_012469.1.7685735. Protein 3e-39 44
D11S_1562 YP_003256146.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686878. Protein 1e-42 43
D11S_1562 YP_003256146.1 macrolide export ATP-binding/permease MacB CP001581.1.gene798.p Protein 4e-33 42