Gene Information

Name : D11S_1219 (D11S_1219)
Accession : YP_003255820.1
Strain : Aggregatibacter actinomycetemcomitans D11S-1
Genome accession: NC_013416
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 1134687 - 1135460 bp
Length : 774 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGACACAATTCACCGTGATCATTCCCGCCCGTTACGCCTCCAGCCGCTTACCGGGCAAACCCTTAGCCGACATTGCCGG
CAAGCCGATGATTAAACACGTTTTTGAACAAGCCAAACAATCCGGTGCCGACCGCGTCATTATCGCCACCGATAACGAAT
TGGTGGCAACCGCCGCAAGAAATTTCGGGGCGGAAGTGTGCATGACCGCCGAAAACCACAATTCCGGCACGGAACGCCTG
GCGGAAGTGGTGGAAAAACTGGCGCTGCCCGACAATGAAATTATCGTCAACATTCAAGGCGACGAACCGCTCATTCCGCC
CGTCATCGTGAAACAAGTGGCGGAAAACCTGGCAAAATACCCTGTGAACATGGCAAGCCTTGCGGTAAAAATTGATGACG
CAGAAGAATTGTTTAATCCCAATGTGGTAAAAGTGCTGACCAACAAAAACGGCTATGTGCTTTATTTCTCCCGCGCCGTG
ATTCCCTGGGATCGCGATCAATTTGCACAAATAGACGATGCGGCAAAGTTACGGCTGAATACCGAATATTTACGTCACAT
CGGCATTTACGCTTACCGTGCCGGATTCATTAAACAATACGTACAGTGGCAGCCGACTGCGCTGGAACACATCGAAAAAC
TGGAACAATTACGCGTGCTTTGGCATGGCGAAAAAATCCATGTAGAACTCGCTAAAGAAGTGCCTGCCGTGGGTGTGGAC
ACCGCCGAAGATCTGGAAAAAGTGCGGTCGATTTTATCGGAGAAATGCCGTTAA

Protein sequence :
MTQFTVIIPARYASSRLPGKPLADIAGKPMIKHVFEQAKQSGADRVIIATDNELVATAARNFGAEVCMTAENHNSGTERL
AEVVEKLALPDNEIIVNIQGDEPLIPPVIVKQVAENLAKYPVNMASLAVKIDDAEELFNPNVVKVLTNKNGYVLYFSRAV
IPWDRDQFAQIDDAAKLRLNTEYLRHIGIYAYRAGFIKQYVQWQPTALEHIEKLEQLRVLWHGEKIHVELAKEVPAVGVD
TAEDLEKVRSILSEKCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-39 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-38 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-39 42