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Name : guaA (D11S_1193) Accession : YP_003255795.1 Strain : Aggregatibacter actinomycetemcomitans D11S-1 Genome accession: NC_013416 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 1107757 - 1109316 bp Length : 1560 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGACCAACATCCATAACCATAAAATCCTCATCCTCGACTTCGGTTCCCAATATACCCAACTCATCGCCCGCCGTGTGCG TGAAATCGGGGTGTATTGTGAGCTTTGGGCGTGGGATGTGACCGAACAACAAATCCGTGATTTCAACCCAACGGGGATTA TTCTTTCCGGTGGTCCGGAAAGCACCACGGAAGAAAACAGCCCGCGCGCACCGGAATATGTCTTTCATGCCGGCGTGCCG GTATTAGGCATTTGCTACGGTATGCAAACCATGGCAATGCAGCTTGGCGGCTTAACGGAAACCTCTGATCACCGCGAGTT CGGTTATGCCTCCGTTTTAATAGAAAATCCGACCGCACTTTTTGCCCATTTAAATGACGGCGACAGCAAATTAGATGTGT GGATGAGCCACGGCGATAAAGTTACCCGCCTGCCGAAGGACTTCCAAATCACCGGCACCACGCCGACCTGCCCGATTGCC GCCATGTCTGATGAAAATCGTCGTTTCTACGGCGTGCAATTCCACCCTGAAGTAACCCACACCAAAAAAGGCTTGGAATT ATTAACCAATTTCGTAGTAAACATTTGTGGTTGCGAAACCAAATGGACGGCAGAAAACATCATTGAAGATGCCGTGGCGC GCATTAAAGCGCAAGTAGGTGATGACGAAGTGATTTTAGGCTTATCCGGCGGCGTGGATTCTTCCGTGGTGGCGCTGTTA TTACATCGCGCTATCGGCAAAAACTTACATTGCGTGTTCGTGGATAACGGTTTATTGCGTTTAAACGAAGGCGTTCAGGT GATGGAAATGTTCGGCGATAAATTCGGTTTGAACATTACCCGTGTTGATGCAGAAAGCCGTTTCTTGAGCGAGTTGGCGG GCGTTTCCGACCCTGAGGCAAAACGTAAAATTATCGGCAAAGTGTTTGTGGATGTGTTCGACGACGAATCGAAAAAACTC ACCAACGTAAAATGGCTCGCGCAAGGCACCATTTATCCTGACGTGATCGAATCCGCCGCCGGCAAAACCGGCAAAGCCCA TGTGATCAAATCCCACCATAACGTAGGCGGCTTGCCGGATTACATGAAATTAGGCTTAGTTGAGCCGTTACGCGAACTAT TCAAAGACGAAGTGCGCAAAATCGGCTTGGCATTAGGCTTACCGGCAGAAATGATCAACCGTCATCCGTTTCCCGGCCCG GGTTTAGGGGTGCGCGTACTCGGCGAAGTGAAAAAAGAATACTGCGATTTATTACGTCGCGCCGATGCAATTTTTATCGA AGAATTGCATAACAACGGTTGGTATGCGAAAACCAGCCAAGCCTTCAGCGTATTCCTGCCGGTGAAATCGGTAGGTGTGA TGGGCGACGGGCGTAAATATGACTGGGTTATCTCCCTGCGCGCCGTAGAAACGATCGATTTTATGACCGCACATTGGGCA CACCTGCCTTATGATTTGCTCGGCAGAATTTCCAATCGCATTATCAATGAAGTAAACGGCATTTCCCGTGTGGTATATGA CATCAGCGGAAAACCACCAGCAACGATTGAGTGGGAATAA Protein sequence : MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEQQIRDFNPTGIILSGGPESTTEENSPRAPEYVFHAGVP VLGICYGMQTMAMQLGGLTETSDHREFGYASVLIENPTALFAHLNDGDSKLDVWMSHGDKVTRLPKDFQITGTTPTCPIA AMSDENRRFYGVQFHPEVTHTKKGLELLTNFVVNICGCETKWTAENIIEDAVARIKAQVGDDEVILGLSGGVDSSVVALL LHRAIGKNLHCVFVDNGLLRLNEGVQVMEMFGDKFGLNITRVDAESRFLSELAGVSDPEAKRKIIGKVFVDVFDDESKKL TNVKWLAQGTIYPDVIESAAGKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMINRHPFPGP GLGVRVLGEVKKEYCDLLRRADAIFIEELHNNGWYAKTSQAFSVFLPVKSVGVMGDGRKYDWVISLRAVETIDFMTAHWA HLPYDLLGRISNRIINEVNGISRVVYDISGKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 7e-131 | 53 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 9e-131 | 53 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 7e-131 | 53 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 1e-110 | 48 |
