Gene Information

Name : hemC (GYMC61_0872)
Accession : YP_003252021.1
Strain : Geobacillus sp. Y412MC61
Genome accession: NC_013411
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 868758 - 869690 bp
Length : 933 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGGAACATTGTCGTTGGCTCGCGGCGCAGCAAGCTTGCCTTGACCCAGACGAAGTGGGTGATCAACGAATTGAAACA
GCTTGGGGCGCCGTTTACGTTTGAAGTGAAAGAAATCGTCACGAAAGGAGATCGGGTGCTTGATGTTACGCTCTCGAAAG
TCGGGGGCAAAGGGTTGTTTGTGAAAGAGATTGAGCATGAATTGCTCGCCGGCGGCATCGATATGGCGGTCCATAGCATG
AAAGATATGCCGGCTGTGCTGCCCGAAGGTTTAGTGATCGGTGCGGTTCCGCGCCGCGAAGATGCACGCGATGTGCTTGT
CAGCAAAGGAAACCGGATGCTCTCCGACTTGCCGCCTGGGTCGGTCATTGGCACGAGCAGCTTGCGCCGTTCGGCGCAGC
TGCTTGCCTATCGCCCGGATTTGACGATCAAATGGATTCGCGGCAATATTGACACAAGGTTGGCGAAGCTCGAAAGCGAA
GAGTACGATGCGATCGTGCTGGCGGCGGCGGGTCTTGCGCGCATGGGTTGGGGCGATGACGTCATCAGCGACTATCTTCC
TTTTGATGTCTGTGTTCCGGCGGTCGGCCAAGGGGCGCTGGCGGTCGAATGCCGGGAGGATGATGACGAATTGCGCCAAT
GGCTCAGCCGGTTAAACGACGAGCAAACCGAGCGGGCTGTTCGGGCGGAGCGCGCCTTTTTGCAGCAAATGGAAGGCGGC
TGTCAAGTGCCGATTGCCGGCTACGCTGAAGCAGACGGCGGCATGGTGCGCCTCACGGCCCTTGTCGCTTCGCCGGATGG
AAAAGAAAAGTATAAAGAAATGGTCACGGGCGCCGATCCGGAGGCCGTCGGCCGGCAGGCGGCCGCTGTCTTGATCGAAC
AAGGGGCGAAAGCGCTCATCGAGCGGGTGAAACAGGAGTTGAGCCAATCATGA

Protein sequence :
MRNIVVGSRRSKLALTQTKWVINELKQLGAPFTFEVKEIVTKGDRVLDVTLSKVGGKGLFVKEIEHELLAGGIDMAVHSM
KDMPAVLPEGLVIGAVPRREDARDVLVSKGNRMLSDLPPGSVIGTSSLRRSAQLLAYRPDLTIKWIRGNIDTRLAKLESE
EYDAIVLAAAGLARMGWGDDVISDYLPFDVCVPAVGQGALAVECREDDDELRQWLSRLNDEQTERAVRAERAFLQQMEGG
CQVPIAGYAEADGGMVRLTALVASPDGKEKYKEMVTGADPEAVGRQAAAVLIEQGAKALIERVKQELSQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-57 47
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-57 47