Gene Information

Name : GYMC61_0744 (GYMC61_0744)
Accession : YP_003251897.1
Strain : Geobacillus sp. Y412MC61
Genome accession: NC_013411
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 734292 - 735782 bp
Length : 1491 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: gka:GK2772 NAD-dependent aldehyde dehydrogenase

DNA sequence :
ATGATTTCTATGAAAACAACAGAAGCTGGTTTATGGATTGGAGGAGAATGGCGGCCGGCGGCGGATGGCGCGATGTTTGA
CGTCATCGACCCGGCGACAGGCCAAGTGACGGCCCGTGTGGCCAACGCCGGGGAAAAAGATGTCGACGCGGCGGTCGCCA
TCGCCGAAGAGGCGTTTTCGGACCGGCGTTGGCTGTCGATTCCGCCGCTCGAGCGCGGGCGCATCTTGCGGCGCATCGCC
GAACTGATCCGCCAGCATCATGATGAACTCGCGCAGCTCATGACGCGGGAAAACGGCATGCCGATCAATCTAGCGTTGTT
TATTGAAATTCCGCTTGCCGCCGACTGCTTCGACTTTTTCGCCTCGCTCGTCGTCAAGCCGCAAGGGGAGGTGCTGCCGT
TTTCCGTCGCCGGCTCGGCGCCGGATTATATGGCGTGGACGATGAAGGAGCCGATCGGGGTGGCTGGGCTCATCACCCCG
TGGAACTTTCCGCTTTTGATGCCGACGTGGAAAATCGCCCCAGCGCTGGCGGCGGGCTGTACGATGGTGTTAAAACCGGC
GCCGGAAACGCCGCTGACGGCGTTGAAGCTTGCTGAGATTTGCCATGAGGCCGGCGTGCCGGAAGGCGTCATCAACGTCC
TGCCTGGACTCGATGAGGCCGGAAAAGCGCTCGTCAGCCACCCTGGCGTGCCGAAAATCGCGTTTACCGGCGAAACGGAA
ACCGGGCGCCGCATCTTGCAAGCGGCCGCTCCCCACATTAAGCGGGTGACGCTCGAGCTTGGCGGGAAGTCGCCGAATAT
CATCTTTGCGGACGCGGATCTTGAACAGGCGGCGAAAAGCGCGCTGTTTGGCGTGTTCTACAATTCAGGGCAAGTGTGCC
AAGCGGGAAGCCGCATTTTAGTCGAACGGCCGGTTTACGAAACGTTTGTCGAGCTGTTGGCCAGCAAAGCGAAAAAGCTG
AAAGTCGGGCCCGGCACGGATGCGCGCAGCGACCTTGGCCCCGTCATCAGCCGGGAGCAATACGAGAAAGTATTGCGCTA
CATTGACATCGGCAAGCAGGAAGGGGCGAAGCTCGTTGCGGGAGGGAGCGCTTTAGATGGGCTTGGCGGCGGCTATTTCA
TTGGACCGACCGTCTTTGCCGATGTATCGCCATCGATGTGCATCGCCCGTGAAGAAATTTTCGGGCCGGTCGCCGCTGTC
ATTCCGTTTCAAGATGAAGAGGAAGCCGCCTCCATTGCCAACGATACGATTTACGGCTTGGCGGCGGCGGTTTGGACGAA
TGACATCAAACGGGCGCTCCGCTTAGCGCGGCGGGTGAAAAGCGGAACCGTGTGGATCAACACGTACCAAGTGCTGTCGC
CGACTGCGCCGTTTGGCGGTTATAAGCAGAGCGGCCTCGGCCGCGAGCTCGGGATGCAGGCGCTTGAAGCGTATTTAGAA
ACGAAAACGGTCATTTGCGACCTCAATGAACGGCCGATGACGTTGTTTTAA

Protein sequence :
MISMKTTEAGLWIGGEWRPAADGAMFDVIDPATGQVTARVANAGEKDVDAAVAIAEEAFSDRRWLSIPPLERGRILRRIA
ELIRQHHDELAQLMTRENGMPINLALFIEIPLAADCFDFFASLVVKPQGEVLPFSVAGSAPDYMAWTMKEPIGVAGLITP
WNFPLLMPTWKIAPALAAGCTMVLKPAPETPLTALKLAEICHEAGVPEGVINVLPGLDEAGKALVSHPGVPKIAFTGETE
TGRRILQAAAPHIKRVTLELGGKSPNIIFADADLEQAAKSALFGVFYNSGQVCQAGSRILVERPVYETFVELLASKAKKL
KVGPGTDARSDLGPVISREQYEKVLRYIDIGKQEGAKLVAGGSALDGLGGGYFIGPTVFADVSPSMCIAREEIFGPVAAV
IPFQDEEEAASIANDTIYGLAAAVWTNDIKRALRLARRVKSGTVWINTYQVLSPTAPFGGYKQSGLGRELGMQALEAYLE
TKTVICDLNERPMTLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-82 46
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 1e-72 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-82 43
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-82 43
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-85 43
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-85 43
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-85 43
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-84 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GYMC61_0744 YP_003251897.1 betaine-aldehyde dehydrogenase VFG0082 Protein 1e-82 43