Gene Information

Name : leuS (GYMC61_0666)
Accession : YP_003251824.1
Strain : Geobacillus sp. Y412MC61
Genome accession: NC_013411
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 653900 - 656317 bp
Length : 2418 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCTTCAACCACCGCGAAATTGAACAAAAATGGCAGGACTATTGGGAGAAAAACAAAACGTTCCGCACGCCCGATGA
TGATGACAAGCCGAAGTTTTACGTTCTCGACATGTTCCCGTATCCATCCGGCGCCGGCTTGCACGTCGGCCATCCGGAAG
GATATACGGCGACCGATATTTTGGCGCGCATGAAGCGGATGCAAGGGTACAACGTCCTTCACCCGATGGGCTGGGACGCG
TTCGGGCTGCCGGCTGAGCAATATGCGCTCGATACCGGCAACGACCCGGCGGAGTTTACGCAAAAAAACATCGACAATTT
CCGCCGGCAAATCAAGTCGCTTGGCTTTTCGTACGACTGGGACCGGGAGATCAATACGACCGACCCGAACTATTACAAAT
GGACGCAATGGATTTTCTTGAAGCTGTATGAAAAAGGGCTCGCCTACATGGATGAAGTGCCGGTCAACTGGTGCCCGGCG
CTCGGCACGGTGCTGGCGAACGAAGAGGTGATCAACGGCCGGAGCGAGCGCGGCGGGCATCCGGTCATCCGCAAGCCGAT
GCGGCAATGGATGCTGAAAATCACCGCCTACGCCGACCGCCTGCTTGAAGATTTGGAAGAGCTCGACTGGCCGGAAAGCA
TTAAAGAGATGCAGCGCAACTGGATTGGCCGTTCGGAAGGAGCGGAAATCGAGTTTGCCGTCGACGGCCATGACGAAACA
TTCACCGTGTTCACGACGCGTCCGGATACGCTGTTTGGCGCGACGTACACCGTCTTGGCGCCGGAGCATCCGCTCGTTGA
GAAAATCACGACGCCGGAGCAAAAGCCAGCCGTTGACGCCTACTTAAAGGAAATTCAAAGCAAAAGCGACCTTGAGCGCA
CCGATTTGGCGAAAGAAAAAACGGGCGTGTTCACCGGCGCATACGCCATTCACCCGGTCACCGGCGATCGGCTTCCGATT
TGGATCGCCGACTACGTCTTGATGAGCTACGGCACCGGAGCGATCATGGCCGTGCCGGCGCACGATGAGCGCGACTACGA
GTTTGCAAAAAAATTCCACTTGCCGATGAAAGAAGTCGTCGCCGGTGGGAATATCGAAAAGGAAGCGTACACCGGAGATG
GCGAGCATATCAACTCCGAGTTTTTGAACGGCTTGAACAAGCAGGAAGCGATCGACAAAATGATCGCCTGGCTTGAGGAG
CACGGCAAAGGGCGGAAAAAAGTGTCGTACCGGCTGCGCGACTGGCTGTTCAGCCGCCAGCGCTACTGGGGCGAGCCGAT
TCCGATCATCCATTGGGAAGACGGCACGATGACGCCGGTGCCGGAAGAGGAATTGCCGCTTGTGTTGCCGAAAACGGATG
AAATCCGTCCGTCGGGAACGGGCGAGTCGCCGCTGGCCAACATCGAAGAATGGGTCAATGTTGTCGACCCGAAAACCGGG
AAAAAAGGGCGGCGCGAAACGAACACGATGCCGCAATGGGCCGGAAGCTGCTGGTATTATTTGCGCTACATCGACCCGCA
CAACGACAAGCAGCTCGCCGATCCAGAAAAGCTGAAAAAGTGGCTGCCGGTCGATGTCTACATCGGCGGGGCGGAGCACG
CGGTCCTGCATTTGCTTTATGCCCGCTTCTGGCATAAGTTTCTTTATGACCTTGGCATCGTGCCGACGAAAGAACCGTTC
CAAAAGCTGTTCAACCAAGGGATGATTTTAGGCGAAAACAACGAAAAAATGAGCAAATCAAAAGGCAACGTCGTCAACCC
GGACGACATCATCGAAAGCCATGGGGCCGACACCTTGCGGCTGTATGAAATGTTCATGGGGCCGCTTGAGGCGTCGATCG
CTTGGTCGACGAAAGGGCTTGACGGGGCGCGGCGCTTCCTCGACCGCGTCTGGAGACTCTTTGTCACCGAGAATGGCGAA
CTGAACCCGAACATTGTCGACGAACCGGCGAACGATACGCTCGAGCGCGTCTATCACCAAACGGTGAAAAAAGTGACGGA
AGACTATGAAGCGCTCCGCTTTAACACCGCCATTTCGCAGCTTATGGTGTTCATCAACGAAGCGTACAAAGCGGAGCAAA
TGAAAAAAGAATACATGGAAGGCTTCGTCAAGCTCTTGTCGCCGGTCTGCCCGCACATCGGCGAGGAGCTGTGGCAAAAG
CTTGGCCACACGGACACGATCGCCTATGAACCGTGGCCGACGTATGATGAAACGAAGCTTGTCGAGGACGTCGTGGAAAT
CGTCGTGCAAATCAACGGCAAAGTGCGGTCGCGTTTGCACGTGCCAGTTGACTTGCCAAAAGAAGCGCTCGAGGAGCGGG
CGCTCGCCGATGAAAAAATCAAAGAGCAGCTTGAGGGCAAAACGGTGCGCAAAGTGATCGCCGTCCCCGGCAAGCTCGTC
AATATCGTCGCCAACTAA

Protein sequence :
MSFNHREIEQKWQDYWEKNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDREINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPA
LGTVLANEEVINGRSERGGHPVIRKPMRQWMLKITAYADRLLEDLEELDWPESIKEMQRNWIGRSEGAEIEFAVDGHDET
FTVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKTGVFTGAYAIHPVTGDRLPI
WIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVAGGNIEKEAYTGDGEHINSEFLNGLNKQEAIDKMIAWLEE
HGKGRKKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTMTPVPEEELPLVLPKTDEIRPSGTGESPLANIEEWVNVVDPKTG
KKGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYARFWHKFLYDLGIVPTKEPF
QKLFNQGMILGENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLDRVWRLFVTENGE
LNPNIVDEPANDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEAYKAEQMKKEYMEGFVKLLSPVCPHIGEELWQK
LGHTDTIAYEPWPTYDETKLVEDVVEIVVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLV
NIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 67