Gene Information

Name : smpB (GYMC61_3124)
Accession : YP_003254164.1
Strain : Geobacillus sp. Y412MC61
Genome accession: NC_013411
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 3173680 - 3174147 bp
Length : 468 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGCCGAAAGGCGAAGGAAAAGTGATCGCCCAAAACAAAAAAGCGCACCACGACTATTTCATCGAAGAGACGTATGAAGC
CGGCCTTGTGCTGCAAGGGACGGAAATCAAATCGATCCGCAACGGCCGGGTGAATTTGAAAGATTCGTTCGCCAAAGTGG
AAAAAGGGGAAGTGTTTCTCCATAACATGCATATCAGCCCGTACGAACAAGGCAACCGCTACAACCATGATCCGCTGCGG
ACAAGAAAGCTCCTTTTGCACCGCCGCGAAATCAACAAGCTGATCGGCTACACGAAAGAGCAAGGGTATACGCTCGTGCC
GCTCAAATTGTATATCAAGAACGGCTTTGCCAAAGTGGAGCTCGGGGTGGCCAAAGGGAAGAAAAAATACGACAAACGGG
AAGACATGAAGCGGAGAGAAGCGCAGCGCGAAATCGAACGGGCGTTTCGCGAGCGGCAAAAACTGTAG

Protein sequence :
MPKGEGKVIAQNKKAHHDYFIEETYEAGLVLQGTEIKSIRNGRVNLKDSFAKVEKGEVFLHNMHISPYEQGNRYNHDPLR
TRKLLLHRREINKLIGYTKEQGYTLVPLKLYIKNGFAKVELGVAKGKKKYDKREDMKRREAQREIERAFRERQKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-43 64
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-35 53
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 4e-29 46