Gene Information

Name : GYMC61_2295 (GYMC61_2295)
Accession : YP_003253382.1
Strain : Geobacillus sp. Y412MC61
Genome accession: NC_013411
Putative virulence/resistance : Virulence
Product : 2-hydroxymuconic semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 2337578 - 2339053 bp
Length : 1476 bp
Strand : +
Note : KEGG: bld:BLi03994 hypothetical protein; TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase

DNA sequence : 
ATGAAAGCAAAAGTGACAGCCAGCGAGAAAGTAAAGGCATTTGACTGCCAACATTTCATCAACGGGCGGTTTTTGCCTTC
GCAAAGCGGCAAGATGTTTCAAAACATTAATCCTGCTACGGGGGAAGTGATCGGCACCGTCTGTGAAGGGGGGAAAGAAG
AGATTGACTTGGCGGTGGCCGCCGCAAAAAGGGCGCTTAGTGGACCATGGAAACGGATGACGACTGGGGAGCGGATCGCG
GTTTTGCGCCGTATCGGCGATCTCATTTTAGAGCGCAAAGAGGAACTGGCTCGCCTCGAGTCGCTCGATACGGGGAAGCC
ATACTCTCTCTCCCTCACGTTGGATATTCCGCGAGCAGCGTATAATTTCCACTTTTTCGCCGACTATTTGCGATCGGTCG
GCACGGAAGCGTATCAGACTGATGAGGTGGCCATCAACTATTCGATCCGCCGACCGGTGGGGGTCGTTGGGCTGATCAAT
CCGTGGAATTTGCCGTTGCTATTGTTGACGTGGAAGCTCGCCCCGTGTTTGGCAGCCGGGAACACGGCCGTCATCAAGCC
GGCGGAATGGACGCCGCTCACCGCAACTGTATTGGCCGAAATTTGCAAAGAAGCCGGGGTGCCGGATGGCGTTGTGAATG
TTGTCCACGGATTCGGTCCGGATTCGGCAGGGGCGGCGTTGACTGAGCATCCGGATGTTGATGCCATTACGTTCACTGGA
GAGACAACAACGGGAAAAGTCATTATGGCGGCGGCGGCGAAATCCTTGAAAAAGCTGTCTTATGAGTTGGGAGGGAAAAA
TCCGAACATCATTTTCGCTGATGCGGATTTGGACGAAGCGATCGAGACGACGTTGAAATCGAGTTTTATGAACCAAGGGG
AAGTGTGTCTGTGCGGATCAAGAATTTATGTAGAGAGGCCGGTTTATGAACAATTTTTGCAAAAGTTTGTGGCCAAAACG
AAAGAACTCGTTGTCGGCGATCCGTTCGATCCGAAAACAAATGTCGGCGCGCTCATCAGCGAAGAGCATTACGAACGGGT
GATGAGCTACATCGAGCTGGCGAAGGAGGAAGGCGGTCGTATTTTAACCGGTGGAAAGCGGCCGGATGGTTTGGATCGAG
GATATTATCTTGAACCGACGATTATTGTCGGTGTCAACCGAAATTGCCGCATCGTCCGCGAAGAAGTGTTCGGACCGGTG
GTGACAGTCATGCCGTTTGACGAAGAAGAGGAAGTGATCGCCCAAGCGAACGACACCCACTACGGATTGAGCGCGACGAT
TTGGACGAACGATTTGCGTCGGGCGCACCGGGTGGCGGCGCGCATTGAAGCCGGAATCGTTTGGGTCAATACGTGGTTTT
TGCGGGATTTGCGCACACCGTTTGGCGGCATGAAACAAAGCGGCATCGGGCGCGAAGGCGGCATGCATAGCTTTGAGTTT
TATACAGAGTTGACGAACATTTGCATTAAGCTTTAG

Protein sequence : 
MKAKVTASEKVKAFDCQHFINGRFLPSQSGKMFQNINPATGEVIGTVCEGGKEEIDLAVAAAKRALSGPWKRMTTGERIA
VLRRIGDLILERKEELARLESLDTGKPYSLSLTLDIPRAAYNFHFFADYLRSVGTEAYQTDEVAINYSIRRPVGVVGLIN
PWNLPLLLLTWKLAPCLAAGNTAVIKPAEWTPLTATVLAEICKEAGVPDGVVNVVHGFGPDSAGAALTEHPDVDAITFTG
ETTTGKVIMAAAAKSLKKLSYELGGKNPNIIFADADLDEAIETTLKSSFMNQGEVCLCGSRIYVERPVYEQFLQKFVAKT
KELVVGDPFDPKTNVGALISEEHYERVMSYIELAKEEGGRILTGGKRPDGLDRGYYLEPTIIVGVNRNCRIVREEVFGPV
VTVMPFDEEEEVIAQANDTHYGLSATIWTNDLRRAHRVAARIEAGIVWVNTWFLRDLRTPFGGMKQSGIGREGGMHSFEF
YTELTNICIKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-85 47
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-65 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-66 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-68 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-68 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-68 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-67 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GYMC61_2295 YP_003253382.1 2-hydroxymuconic semialdehyde dehydrogenase VFG0082 Protein 1e-66 42