Gene Information

Name : GYMC61_1668 (GYMC61_1668)
Accession : YP_003252783.1
Strain : Geobacillus sp. Y412MC61
Genome accession: NC_013411
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1686246 - 1687424 bp
Length : 1179 bp
Strand : +
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGGAACAGGAATGGGCGTTTTCGACGAAACTGCTCCATAACGAATGGAAAGTCGACCGCGAAACGGGGGCGGTGAGCGT
GCCGATCCAGCACGCCTCCACGTTCCATCAGTTCGATTTCGATTCATTCGGCAAATACGACTACAGCCGCTCCAGCAACC
CGACGCGCGAGGCGCTTGAGGAAACGATCGCGGCGTTAGAAGGCGGAACGCGCGGGTTTGCGTTCGCCTCTGGTATGGCG
GCTATTTCAACGGCGTTTTTGCTTCTCTCAAAAGGCGACCACGTGCTTGTGACCGAAGACGTCTATGGCGGCACGTACCG
GATGGTTACGGAGGTGCTCGGCCGCTTTGGCATTGAATATACGTTTGTCGATATGACCGATTTAAACGCAGTGGCGGAAA
ACATCCGGGCGAACACGAAAGTCATTTATATGGAAACGCCGTCCAATCCATTGTTAAAAGTGACCGATATTCAAGGCGTC
GTCAAGTTGGCGAAGGCGCATGGCTGTTTGACATTCTTGGATAATACGTTCATGACGCCGGCGCTGCAGCGGCCGCTTGA
TCTTGGAGTCGATGTCGTCCTTCACAGCGCCACGAAATTTTTAGCCGGCCATAGCGACGTCGTCGCAGGATTGGCGGTGG
TGAAAGATGAAGAATTGGGAAAAGAATTGTACAAACTGCAAAACGCGTTTGGCGCTGTCCTTGGCGTCCAAGATGCGTGG
CTTGTGCTGCGGGGATTAAAAACGCTCCACGTTCGGCTGAAGCAGTCGTCTGAATCAGCGGCCGCCATCGCCAAGTATTT
GGCTTGTCATCCAAAGGTCGAAAAAGTGTATTATCCGGGGCTTTCGCACCACCCAGGCCATGACATCCAGCGCCATCAGG
CGGCCGGGTTTGGCGCTGTGCTGTCGTTCCGCTTAGCCGATGAAGAAGCGGCTCGGACGTTCGTCCGAAACGTCCGCCTG
CCGGTGTTTGCTGTCAGCCTTGGGGCGGTCGAGTCAATTTTATCGCATCCAGCGAAAATGTCGCATGCGGCGATGCCAAA
AGAAGAGCGGCTCCGGCGCGGCATTACCGACGGCTTGCTGCGGCTGAGCGTCGGGCTTGAGGATGTGAACGATTTGATCC
GCGATTTCGAGCAGGCGTTGTCGTTTGTGAAAGAGCGGCCGTCGGTTTCAACGACATAG

Protein sequence :
MEQEWAFSTKLLHNEWKVDRETGAVSVPIQHASTFHQFDFDSFGKYDYSRSSNPTREALEETIAALEGGTRGFAFASGMA
AISTAFLLLSKGDHVLVTEDVYGGTYRMVTEVLGRFGIEYTFVDMTDLNAVAENIRANTKVIYMETPSNPLLKVTDIQGV
VKLAKAHGCLTFLDNTFMTPALQRPLDLGVDVVLHSATKFLAGHSDVVAGLAVVKDEELGKELYKLQNAFGAVLGVQDAW
LVLRGLKTLHVRLKQSSESAAAIAKYLACHPKVEKVYYPGLSHHPGHDIQRHQAAGFGAVLSFRLADEEAARTFVRNVRL
PVFAVSLGAVESILSHPAKMSHAAMPKEERLRRGITDGLLRLSVGLEDVNDLIRDFEQALSFVKERPSVSTT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-92 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-86 50
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-85 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GYMC61_1668 YP_003252783.1 cystathionine beta-lyase BAC0207 Protein 7e-66 42