Gene Information

Name : GYMC61_0979 (GYMC61_0979)
Accession : YP_003252126.1
Strain : Geobacillus sp. Y412MC61
Genome accession: NC_013411
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 978932 - 980065 bp
Length : 1134 bp
Strand : +
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGAGGCGGAAAACAATGCTCATTCATGGCGGCATTCCGGGGGATCCGCATACTGGAGCGGTGTCGGTTCCGATTTATCA
AGTGAGTACGTATAAGCAAGAAGAAGTTGGAAAGCATAAAGGGTTTGAATACTCGCGCACCGGCAACCCGACGCGCGCGG
CGCTTGAGAAGCTGATCGCCGATCTCGAGGGCGGCGAAGCCGGCTTTGCGTTCGCTTCCGGTATGGCGGCAATTACGGCC
GTCATGATGTTGTTTCAAAGCGGCGACCATCTGGTGCTCACTGACGATGTCTACGGCGGCACGTATCGCGTCATGACGAA
CGTGCTGAATCGGTTCGGGCTTGAGGCGACGTTCGTCGATACGAGCGATGTCGCCAACATCGAGGCGCACATCCGGCCGA
ATACGAAAGCCATCTATATCGAAACGCCGACGAACCCGCTGTTGAAAATCACTGACTTGCAAGCCGCCGCCGCCATTGCC
CGTGCGCATGGGCTGCTATTGATCGTCGATAACACGTTTTCCACTCCGTACTTTCAGACGCCGCTTGAGCTTGGCGCCGA
TATCGTCATTCATAGCGCGACGAAATATTTAGGCGGCCATAGCGACGTCGTCGCTGGGTTGGCGGTTGTCCGCACGCCGG
AGCTTGCCGAACGGCTCCATTACGTGCAAAATTCAACCGGCGGCGTGCTCGGGCCGCAGGATTCATGGTTATTGATGCGC
GGGATGAAAACGCTCGCCGTGCGGATGGAGGAACATGAAGAAAATGCGCGCCAAATCGCTGTTTTTTTGGCTGAACACAA
GGTGGTCAAGCGCGTCCATTACCCCGGGCTTCCGGATCATCCGAACCACGAGCTGGCGAAAAAACAAATGCGCGGATTTG
GCGGCATGATTTCGTTTGATGTCGGCAGCTTGGAGCGCGCCGAGAAAGTGCTGTCGCGCGTGCGCTACTTTACGCTTGCC
GAAAGCTTAGGGGCGGTCGAAAGTTTAATTTCGTTGCCAGGGAAAATGACGCACGCCTCGATCCCGAAGGAACGGCGCGA
ACAGCTCGGCATTACCGACGGCCTGATCCGTTTGTCGGTCGGGCTTGAAGATGTCAACGATCTGCTTGACGATTTGGCGC
AGGCGCTTGGCTGA

Protein sequence :
MRRKTMLIHGGIPGDPHTGAVSVPIYQVSTYKQEEVGKHKGFEYSRTGNPTRAALEKLIADLEGGEAGFAFASGMAAITA
VMMLFQSGDHLVLTDDVYGGTYRVMTNVLNRFGLEATFVDTSDVANIEAHIRPNTKAIYIETPTNPLLKITDLQAAAAIA
RAHGLLLIVDNTFSTPYFQTPLELGADIVIHSATKYLGGHSDVVAGLAVVRTPELAERLHYVQNSTGGVLGPQDSWLLMR
GMKTLAVRMEEHEENARQIAVFLAEHKVVKRVHYPGLPDHPNHELAKKQMRGFGGMISFDVGSLERAEKVLSRVRYFTLA
ESLGAVESLISLPGKMTHASIPKERREQLGITDGLIRLSVGLEDVNDLLDDLAQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-96 57
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-97 57
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-73 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GYMC61_0979 YP_003252126.1 cystathionine beta-lyase BAC0207 Protein 1e-63 46