Gene Information

Name : guaA (Fisuc_2984)
Accession : YP_003251046.1
Strain : Fibrobacter succinogenes S85
Genome accession: NC_013410
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3677810 - 3679645 bp
Length : 1836 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAAAACGTTGATACTATTGCCGTTTTGGACTTTGGTGGGCAGTATGCTCACTTGATTGCCAACCGTGTACGCCGTCT
TGGCGTGTTTACCGAAATCCACTCCCCTGCCGCCCCGGTTTCTGAACTCGAAGGCGTGAAGGGCATCATTTACAGTGGCG
GTCCGTCTAGCGTTTATGCGGCTGACGCTCCGGAATACAATCCTGAAATTTTGAACCTCCCGGTGCCGAAGCTCGGCATC
TGCTACGGCCACCAGCTCATCGCCCAGCAGTTGGGCGGTCACGTGGAACCGGGCAAGGTCAAGGAATACGGCATTGCAGA
CCTCATCGTGGGCGATGAAAAATGCCCGCTTTTGAAGGGTCTCCCGAAAGCATCCCCGATGTGGATGAGCCATGGCGACC
AGGTCACCAAGCTTCCCGAAGGCTACAAGATTGTGGCAAGCACCAAGGACTGCGAAATCGCCGCCGTTGCATTTGATAGC
GATAAGCCTGAACGCCAGATTTTCGGCATCCAGTTCCATCCCGAAGTCACGCACAGCAAGTTCGGCATGAAGCTTCTCGA
AAACTTCGTCGACTTTACGGGCGCCAAGAAGACTTGGAACATGAAGAGCTACTTGCCGCTCATCACGCAGCGCATTAAGG
ACCAAGTCAAGGACCGCAAGGTGTTCTTACTCGTCTCCGGTGGCGTGGACTCCACCGTGGCATTTGTGCTCTTGAACCGC
GTGCTCGGACCGGAAAAAGTTCTCGGCTTGCATGTGGATAACGGCATGATGCGCCTCGGCGAATCCCAGAAGATTATGGA
CTTCCTCACGAAGGAAGGTATGAACAACCTCAAGATCCGTGACGCTAGCAAACACTTCCTTGCCAAGCTCAAGGGCGTGA
CTGCTCCGGAAACCAAGCGCGGCATCATCGGTAAGGAATTCTTGACGGTCAAGGACGAGGAAATGGCTAAGCTCAACCTC
GATCCGAACGAATGGATGATGGCACAAGGTACCATCTACCCCGACACCATCGAAAGCGGCGGCACCAAGAATGCCGACAA
GATCAAGACGCACCACAACCGCGTGCAAGAAGTTTTGGACCTCATGGAAAAGGGTCTCGTCTTGGAACCGCTCGCCGACT
TGTACAAGGACGAAGTCCGCGCACTCGGCGAAGAACTCGGCATTCCGCACAACCTCGTGTGGCGCCACCCGTTCCCGGGT
CCAGGTCTCGGCGTTCGTTTGCTCTGCAGCGAAGGCAAGCTCACAAGCGACATGGTAAAGTTCGAAGACGTGAAGGACAC
CGCAGGTCAGTCCCTCGCCGATTACCTCAAGGCAAACAACATTGCTGGTCGCATGCTCCCGATTAAGAGCGTTGGCGTCC
AGGGTGACGGCCGTACTTACGCACAGCCGTTCCTCATCACCACTCCGGGCCTCAGCTGGAAGGAATGCGAAAAGTTCTCT
ACAGAACTTGCCAACCGCTTCAAGGCCATCAACCGCGTGATTTACCAGATTGGTAGCGTGGCAGACGAAGATCCGAAGCT
TGTTGAACAGTACGCCACCCGCGAAAACTTCGATACGCTCCGCAAGTTCGACAACATCTGCACCGAATTCTTGCAGGCAA
ACGACTTGTACGAAAAGATTTGGCAGATGCCGGTCGTGCTCGTTCCGCTCCGCACGGCTAACAAGCCCTGCATCGTGATG
CGCCCAGTGAACTCCACCGAAGCCATGACGGCAAACTTCGCCGAAATCGACCAGGGAATGCTCGCCGGTCTCTGGCGCAA
GTTCGAAGCCGAAGGCGCTGGCAGCCTGTGGTACGACGTGACGCACAAGCCCCCCGGAACCATTGAGTGGGAGTAA

Protein sequence :
MKNVDTIAVLDFGGQYAHLIANRVRRLGVFTEIHSPAAPVSELEGVKGIIYSGGPSSVYAADAPEYNPEILNLPVPKLGI
CYGHQLIAQQLGGHVEPGKVKEYGIADLIVGDEKCPLLKGLPKASPMWMSHGDQVTKLPEGYKIVASTKDCEIAAVAFDS
DKPERQIFGIQFHPEVTHSKFGMKLLENFVDFTGAKKTWNMKSYLPLITQRIKDQVKDRKVFLLVSGGVDSTVAFVLLNR
VLGPEKVLGLHVDNGMMRLGESQKIMDFLTKEGMNNLKIRDASKHFLAKLKGVTAPETKRGIIGKEFLTVKDEEMAKLNL
DPNEWMMAQGTIYPDTIESGGTKNADKIKTHHNRVQEVLDLMEKGLVLEPLADLYKDEVRALGEELGIPHNLVWRHPFPG
PGLGVRLLCSEGKLTSDMVKFEDVKDTAGQSLADYLKANNIAGRMLPIKSVGVQGDGRTYAQPFLITTPGLSWKECEKFS
TELANRFKAINRVIYQIGSVADEDPKLVEQYATRENFDTLRKFDNICTEFLQANDLYEKIWQMPVVLVPLRTANKPCIVM
RPVNSTEAMTANFAEIDQGMLAGLWRKFEAEGAGSLWYDVTHKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-85 42
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-85 42
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-85 42