Gene Information

Name : Fisuc_1079 (Fisuc_1079)
Accession : YP_003249166.1
Strain : Fibrobacter succinogenes S85
Genome accession: NC_013410
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1334943 - 1336100 bp
Length : 1158 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: hhe:HH0062 cystathionine gamma-synthase

DNA sequence :
ATGTCAAACTTCAACAATATCGAAACAAAACTCATTCACGGCGGCATTGATGGCGACAAAACTACAGGAGCTGTAAACGT
CCCTATCTACCAGACTTCCACCTACAAGCAGGCAGGCCTTGGTGAAAACACGGGTTGGGAATATTCCCGCACAGGGAACC
CGACGCGCGCAGCATTGGAAACGCTGATTGCAGAACTCGAAGGAGGAGTCGCAGGCTTTGCATTTGCAAGCGGTATGGCT
GCAACAACAACCGTCCTTTCGCTTTTTAAGCAAGGAGACCGCATCATCATTTCGAGCAATGTCTATGGCGGCACTTTCCG
CGTTTTGGACAAAGTTTTCAAGAATCTCGGAATTACTTATTCCATCGAAGACACGACCGATTTGAAATTGCTTGAATCCA
AAATAACACCCGATGTGAAAGCATTCTTTGTCGAAAGCCCTGCAAATCCGCTCTTGACGGTAACAGACTTGGCAGGCGTT
GCCGCAATTGCCAAGAAGCACAACATTTTGACCATTGTCGATAACACATTTATGACGCCGTATCTGCAGCGTCCGATTGA
ATTGGGTGCTGACATTGTCGTGCATTCTGCGACAAAGTATTTAGGCGGTCACAGCGACTTGGTGGCAGGGCTTGCTGTTG
TCAATTCCAAGGAACTCGCTGAAAGACTCGCTTTTACGCAGAACGCAACCGGTGCTGTACTCGGACCTTTTGATTCATTC
CTCTTAATTCGCGGCATCAAGACGCTTGGCGTCCGCTTGGATCGTCATACTGAAAATGCCGAAACCATCGCAAAGTATCT
CGAAAAGCACGAAGCCGTAAAGCACGTGTATTATCCGGGACTCCCGACAGCACAAGGCTACGAAATCAACAAGAAACAGG
CCAAGAACGGTGGCGCTATGATTTCGTTCGAACTTCGTGAAAATTACGATATCAAAAAATTCTTCAAAGCTCTGAAACTC
GTTTCTCTTGCTGAAAGCTTGGGCGGAGTCGAAAGCCTCGTGTGCCATCCAGCCACAATGACGCATGCATCTATCCCAAA
GGAAATTCGCGAAAAAGTCGGCATCACTGACGGGCTCATTCGCTTATCCGTGGGCATTGAAAAAGTTGACGACATCATCG
CAGATGTTAACGCAGCCATTGAAGCCGCAAAAGCATAA

Protein sequence :
MSNFNNIETKLIHGGIDGDKTTGAVNVPIYQTSTYKQAGLGENTGWEYSRTGNPTRAALETLIAELEGGVAGFAFASGMA
ATTTVLSLFKQGDRIIISSNVYGGTFRVLDKVFKNLGITYSIEDTTDLKLLESKITPDVKAFFVESPANPLLTVTDLAGV
AAIAKKHNILTIVDNTFMTPYLQRPIELGADIVVHSATKYLGGHSDLVAGLAVVNSKELAERLAFTQNATGAVLGPFDSF
LLIRGIKTLGVRLDRHTENAETIAKYLEKHEAVKHVYYPGLPTAQGYEINKKQAKNGGAMISFELRENYDIKKFFKALKL
VSLAESLGGVESLVCHPATMTHASIPKEIREKVGITDGLIRLSVGIEKVDDIIADVNAAIEAAKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-91 52
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-93 52
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-67 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Fisuc_1079 YP_003249166.1 cystathionine gamma-synthase BAC0207 Protein 2e-75 46