Gene Information

Name : Adeg_0440 (Adeg_0440)
Accession : YP_003238442.1
Strain : Ammonifex degensii KC4
Genome accession: NC_013385
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 450572 - 452332 bp
Length : 1761 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; KEGG: dps:DP3116 pyruvate kinase

DNA sequence :
GTGCTACGGCACACCAAGATAGTCTGCACCATAGGGCCGTCAAGCTCAAACCCGGCGGTAATCGAGAGCCTGCTCCGGGC
GGGCATGGACGTGGCCCGGATAAACATGTCGCACGGCACGCAGGAGGAGCACCGGCAGAGGATCAGGCTTTTGCGGGAGA
TAGCCCAGCGGCTGGTAAAGAACCTCGGCATCCTGGTGGACATCCGGGGCCCGCGGATAAGAATAGGCGAGCTTCAGGGA
GGCAAGGTGGAGCTCCGGGAAGGGGAAGAGGTAGAGCTCGTTCCTGGAGACTTTCTGGGCACTTCCTCCCGCCTGCCGGT
AAACTACCCGGGTATCGTAGAGGACCTCAAACCCGGCGATCCGGTACTGCTGGCTGACGGGCTCATCGGCCTGCGGGTAA
AGGAGGTTTCTCCTTCCGGGGTCAGGTGCCGGGTAGAGGCGGGCGGGGAGCTTACTCCTCACAAGGGGGTCAACCTGCCG
GGGGTCAAGGTCAATCTGCCCTCCCTCACCGAGAAGGATGTGGAGGATATAAAGTTTGCCGTGAGCGAGCGGGTGGATTT
CTTAGCCCTCTCCTACGTGCGCCGGGCCGACGACGTGCTGGCGGCCCGGCGCCTCCTGGAGGAGCTGGGGGCAGGAGATC
TCTGGCTCATTGCCAAGATCGAAAACCGCGAGGGTGTGGAGAACCTGCATGCCATTTTAAAGGTGGCCGACGGTGTGATG
GTAGCCCGGGGGGATTTGGGACTGGAGATTCCCCTGGAGGAAGTTCCTTTGGTGCAAAAAGAGATTATTTCCCGCGCCAA
CGCCGCCGGTAAGCCGGTGATCACGGCTACCCAGATGCTGGAGTCCATGATCCAGCACCCGCGCCCCACCCGGGCCGAGG
TGGCCGACGTGGCTAACGCCATCCTGGACGGCACCGACGCGGTCATGCTCTCTGCTGAGACGGCCATCGGGCATTACCCG
GCGGAGACGGTGGCTACCATGGCTCGCATCGCGAGCCGAACCGAAGAGGCTTTCTCCTATGAGGATTCGCTGGAGCGCCG
GCGGGAGACACAGGCCAAGCACACCGTAACCGATGCCATAAGTTTCGCCACCTGTGCCGCCGCCCGGGACCTGGGGGCGG
CGGCCATAATCACCGCTACTCAGACCGGCTACACGGCCCGCATGGTGGCAAAGTACCGGCCACGGGCTCCTATCCTGGCG
GCGACGCCGCGGGTGGAAGTGATGCGGCGCCTAGCCTTGGTCTGGGGGGTATACCCTATCTTAGTGGAGCGTATGGAGAA
TACCGACCAGATGATAGATGAGGCGGTACGGGCGGCCATGGCCTCCGGCTACATCAAGTCAGGGGATCTGGTGGTAATAA
CGGCCGGCGTGCCCGTAGGAGTACACGGTACTACCAATCTTTTGAAGGTGCATACCGTGGGAGATGTGCTGGCACGAGGG
ATGGGCATAGGAGCCAAGTCGGTAACGGGAAGGGTAAGAATAGCGAAGACCGCCAAAGAAGCCCTGGAGAAGGTACAGCC
GGGGGACATTTTGGTGGCCCCGGCCACGGACAAAGAGTATATCCCGGCCATTCGGAAGTGCGCCGGGATCGTCACCGAAG
TGGGAGGGGTAACCTCCCACGCGGCCATCGTGGGCCTGGAGTTCGGCATCCCGGTCATCGTGGGGGTGGAAGGGGCTACG
GCCATCCTGCAGGACGGCCAGGAAGTGACCCTGGATGGGCAGAGGGGTATCATTTACCGGGGCTCGGCGCGGGTACTCTA
G

Protein sequence :
MLRHTKIVCTIGPSSSNPAVIESLLRAGMDVARINMSHGTQEEHRQRIRLLREIAQRLVKNLGILVDIRGPRIRIGELQG
GKVELREGEEVELVPGDFLGTSSRLPVNYPGIVEDLKPGDPVLLADGLIGLRVKEVSPSGVRCRVEAGGELTPHKGVNLP
GVKVNLPSLTEKDVEDIKFAVSERVDFLALSYVRRADDVLAARRLLEELGAGDLWLIAKIENREGVENLHAILKVADGVM
VARGDLGLEIPLEEVPLVQKEIISRANAAGKPVITATQMLESMIQHPRPTRAEVADVANAILDGTDAVMLSAETAIGHYP
AETVATMARIASRTEEAFSYEDSLERRRETQAKHTVTDAISFATCAAARDLGAAAIITATQTGYTARMVAKYRPRAPILA
ATPRVEVMRRLALVWGVYPILVERMENTDQMIDEAVRAAMASGYIKSGDLVVITAGVPVGVHGTTNLLKVHTVGDVLARG
MGIGAKSVTGRVRIAKTAKEALEKVQPGDILVAPATDKEYIPAIRKCAGIVTEVGGVTSHAAIVGLEFGIPVIVGVEGAT
AILQDGQEVTLDGQRGIIYRGSARVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-72 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-71 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-72 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-72 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Adeg_0440 YP_003238442.1 pyruvate kinase VFG0479 Protein 3e-72 44