Gene Information

Name : escN (ECO111_3752)
Accession : YP_003236088.1
Strain : Escherichia coli 11128
Genome accession: NC_013364
Putative virulence/resistance : Virulence
Product : translocator EscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 3737104 - 3738444 bp
Length : 1341 bp
Strand : -
Note : Integrative element ECO111_IE05

DNA sequence :
ATGATTTCAGAGCATGATTCTGTATTGGAAAGATACCCACGTATTCAGAAAGTGCTCAATAGCACTGTGCCGGCATTATC
ATTAAATTCGTCTACCAGATATGAAGGTAAAATTACCAATATCGGCGGGACGATTATTAAGGCGCGTTTACCAAAAGCGC
GTATTGGCGCCTTTTACAAGATAGAACCCAGTCAACGTTTAGCCGAGGTGATCGCTATTGATGAAGATGAGGTTTTCCTG
TTGCCTTTTGAGCATGTTTCCGGCATGTACTGTGGTCAGTGGTTAAGTTATCAGGGGGATGAGTTCAAGATTCGTGTTGG
AGACGCACTACTTGGGCGGCTTGTTGATGGCATTGGCAGACCAATGGAGAGTAATATTGCTGCTCCCTATCTTCCGTTTG
AACGCAGCTTGTATGCTGAACCACCAGATCCTTTATTAAGGCAGGTTATTGATCAGCCATTTATACTTGGCGTCAGGGCA
ATTGATGGGTTACTAACTTGCGGTATTGGGCAGCGTATCGGTATTTTTGCCGGTTCAGGCGTTGGTAAAAGTACGCTTTT
GGGGATGATTTGTAATGGCGCATCCGCAGATATTATTGTCCTTGCTCTTATCGGCGAACGTGGTCGCGAAGTAAATGAAT
TCCTCGCGCTTTTACCTCAATCCACGCTTTCTAAATGTGTGCTGGTCGTCACAACGTCAGACCGCCCCGCACTGGAAAGG
ATGAAAGCCGCATTTACGGCGACGACTATTGCAGAGTACTTCCGCGATCAGGGTAAAAATGTATTATTAATGATGGATTC
TGTAACTCGTTATGCCCGAGCCGCGCGTGATGTTGGGCTTGCATCGGGAGAACCTGATGTAAGGGGGGGATTCCCTCCGA
GTGTTTTTTCCTCGTTACCTAAATTATTAGAGCGAGCGGGGCCTGCGCCAAAAGGTTCAATAACCGCGATTTATACGGTG
TTGTTAGAAAGCGATAATGTTAATGATCCTATTGGCGATGAAGTCCGCTCTATTCTTGATGGGCATATCGTACTTACCCG
AGAACTTGCAGAGGAAAACCATTTCCCTGCAATTGATATTGGTTTAAGTGCCAGTCGTGTTATGCATAACGTTGTTACAT
CGGAGCATTTGCGTGCGGCGGCAGAATGCAAAAAGCTTATTGCGACTTATAACAATGTTGAGCTGCTTATTCGTATTGGT
GAGTACACGATGGGGCAAGATCCTGAAGCGGATAAGGCAATAAAAAATAGGAAATTAATTCAGAGCTTTATACAGCAAAG
CACCAAAGATATCAGTAGTTACGAAAAAACGATTGAAAACCTATTCAAAGTGGTTGCCTGA

Protein sequence :
MISEHDSVLERYPRIQKVLNSTVPALSLNSSTRYEGKITNIGGTIIKARLPKARIGAFYKIEPSQRLAEVIAIDEDEVFL
LPFEHVSGMYCGQWLSYQGDEFKIRVGDALLGRLVDGIGRPMESNIAAPYLPFERSLYAEPPDPLLRQVIDQPFILGVRA
IDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALLPQSTLSKCVLVVTTSDRPALER
MKAAFTATTIAEYFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKLLERAGPAPKGSITAIYTV
LLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRAAAECKKLIATYNNVELLIRIG
EYTMGQDPEADKAIKNRKLIQSFIQQSTKDISSYEKTIENLFKVVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escN YP_003236088.1 translocator EscN Virulence LEE Protein 0.0 100
escN AAC38383.1 EscN Virulence LEE Protein 0.0 99
escN AAC31513.1 L0034 Virulence LEE Protein 0.0 99
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 0.0 99
escN NP_290268.1 hypothetical protein Virulence LEE Protein 0.0 99
ECs4568 NP_312595.1 EscN Virulence LEE Protein 0.0 99
escN AAL57542.1 EscN Virulence LEE Protein 0.0 97
escN CAI43874.1 EscN protein Virulence LEE Protein 0.0 97
escN CAC81862.1 EscN protein Virulence LEE II Protein 0.0 97
escN YP_003223475.1 translocator EscN Virulence LEE Protein 0.0 97
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 0.0 97
escN AAK26715.1 EscN Virulence LEE Protein 0.0 97
unnamed AAL06369.1 EscN Virulence LEE Protein 0.0 95
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-161 78
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-161 78
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-91 52
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 7e-92 51
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-92 51
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-92 51
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 8e-92 51
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-91 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-86 51
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-86 51
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-84 51
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-85 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-84 51
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-86 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-86 51
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-99 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-82 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-82 49
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-71 49
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-71 49
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-71 49
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-71 49
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-69 48
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-82 47
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-76 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-76 47
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-76 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 6e-72 47
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-68 47
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-70 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-71 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 8e-66 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 6e-71 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 6e-70 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-66 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-66 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-69 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
escN YP_003236088.1 translocator EscN VFG0730 Protein 0.0 99
escN YP_003236088.1 translocator EscN VFG0812 Protein 0.0 99
escN YP_003236088.1 translocator EscN VFG0390 Protein 2e-94 52
escN YP_003236088.1 translocator EscN VFG0515 Protein 4e-92 51
escN YP_003236088.1 translocator EscN VFG0192 Protein 2e-95 51
escN YP_003236088.1 translocator EscN VFG0048 Protein 4e-91 51
escN YP_003236088.1 translocator EscN VFG1778 Protein 3e-70 50
escN YP_003236088.1 translocator EscN VFG2144 Protein 1e-85 49
escN YP_003236088.1 translocator EscN VFG0555 Protein 1e-71 49
escN YP_003236088.1 translocator EscN VFG1254 Protein 2e-76 47
escN YP_003236088.1 translocator EscN VFG2499 Protein 1e-74 46
escN YP_003236088.1 translocator EscN VFG2459 Protein 5e-69 45
escN YP_003236088.1 translocator EscN VFG2331 Protein 3e-71 45
escN YP_003236088.1 translocator EscN VFG1008 Protein 3e-65 44