Gene Information

Name : tir (ECO111_3745)
Accession : YP_003236081.1
Strain : Escherichia coli 11128
Genome accession: NC_013364
Putative virulence/resistance : Virulence
Product : putative translocated intimin receptor Tir
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3731500 - 3733155 bp
Length : 1656 bp
Strand : -
Note : Integrative element ECO111_IE05

DNA sequence :
ATGCCTATTGGTAACCTTGGTAATAATGTAAATAGCAATAATTTAATTCCGCCTGCGCCGCCACTACCTTCACAAACAGA
CGGCGCGTCACGGGGAGGAGCGGGTCAACTAATTAACTCTACAGGAGCATTAGGATCTCGTTTATTGTTTTCTCCCCTGA
GAAATTCTATAGCTGATTCTGTCGATTCCAGAGATATTCCAGGACTTCCTGTACACCCATCGAGGCTTGCTACTGCTACA
TCAGAGATATGCTTGCTTGGAGGATTTGAAGTTCTCCATGATAAGGGACCACTTGATACTCTCAATAAGCAAATTGGAGC
CTCTGCATTTCGTATTGAACAGCAGTCAGATGGTTCTTATGCCGCTATTGGAGAAAAAAATGGTGTAGAGGTTAGCGTTA
TATTAAATTCTCAAGAATTGCAAAGCTTGCAAGCTATCGATATTGAGGATAAAGGCCGATTTGTTTTTACCGGGGGACGT
GGTGGTGGTGGGCATTCCATGGTCACTCCTGCATCAGATATCGCAGAAGCTCGTGCGAAAATACTGGCCAAATTAGACCC
AAACAATCATGGGGGAAGTCAAGCCAGGAACGTTGATACGCGTTCTGTTGGTGTTGGAAGTGCTTCGGGAATGGATGATA
GCGTTGTTAGCGAAACTCGTACTTCATCAACAGCTTCCAGCGTTCGTTCAGATCCTAAATTCTGGGTTTCTATCGGCGCA
ATTGCTGCTGGTTTAGCGGGGCTGGCGGCTACTGGTATTACACAGGCGTTGGCTTTGACACCGGAACCGGATGATCCTAC
AACCACCGATCCTGAGCAGGCTGCAAGTGCTGCAGAAAGTGCGACAAGAGATCAGTTAACGCAAGAAGCATTCAAGAATC
CTGAGAACCAGAAAGTTAGCATTGATGAGATCGGAAATTCTATTCCGTCTGGGGAATTAAAAGATGATGTTGTTGCTAAA
ATAGAAGAACAAGCTAAAGAGGCGGGTGAGGCGGCCAGACAGCAGGCTGTTGAAAGCAATGCACAGGCGCAGCAGCGATA
TGATACTCAGTATGCCAGACGTCAGGAGGAATTAGAGCTTTCATCGGGTATTGGTTACAGCCTCAGCAGTGCATTGATTG
TTGGTGGGGGAATTGGTGCTGGTGTAACGACTGCGCTTCATAGACGAAATCAGCCGGCAGAACAAACAACGACAACAACA
ACACATACGGTAGTGCAGCAGCAGACCGGAGGGAATACCCCAGCACAAGGTGGCACTGATGCCATAAGAGCGGAAGACAC
ATCTCTGAATAGACGTGATTCGCAGAGGAGTACGGCATCGACACACTGGTCAGATACTTCTAGCGCAGTGGTTAATCCAT
ATGCTGAAGTTGGGGAGGCTCGGAATAGTTCACCGGCTCGTCAGGCAGAAGAGCATATTTACGATGAGGTCGCTGCAGAT
CCTAATTATAGCGTCATTCAAAATTTCTCAGGGAATAACCAAGTTACCGGAAGGTTAATGGGAACTCCAGGGCAAGGTAT
CCAAAGTACTTATGCGATTCTGACAAACAACAGCGCTGGATTGCGTTTAGGTATGGGTGGATTAACGGGGAGTGGCGGGA
GCGCAGTAAATACTGCAAATGCCGCACCAACGCCGGGACCAGGACGTTTCGTTTAA

Protein sequence :
MPIGNLGNNVNSNNLIPPAPPLPSQTDGASRGGAGQLINSTGALGSRLLFSPLRNSIADSVDSRDIPGLPVHPSRLATAT
SEICLLGGFEVLHDKGPLDTLNKQIGASAFRIEQQSDGSYAAIGEKNGVEVSVILNSQELQSLQAIDIEDKGRFVFTGGR
GGGGHSMVTPASDIAEARAKILAKLDPNNHGGSQARNVDTRSVGVGSASGMDDSVVSETRTSSTASSVRSDPKFWVSIGA
IAAGLAGLAATGITQALALTPEPDDPTTTDPEQAASAAESATRDQLTQEAFKNPENQKVSIDEIGNSIPSGELKDDVVAK
IEEQAKEAGEAARQQAVESNAQAQQRYDTQYARRQEELELSSGIGYSLSSALIVGGGIGAGVTTALHRRNQPAEQTTTTT
THTVVQQQTGGNTPAQGGTDAIRAEDTSLNRRDSQRSTASTHWSDTSSAVVNPYAEVGEARNSSPARQAEEHIYDEVAAD
PNYSVIQNFSGNNQVTGRLMGTPGQGIQSTYAILTNNSAGLRLGMGGLTGSGGSAVNTANAAPTPGPGRFV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tir YP_003236081.1 putative translocated intimin receptor Tir Not tested LEE Protein 4e-175 100
tir AAY25393.1 translocated intimin receptor Virulence LEE Protein 1e-173 99
tir AAY25395.1 translocated intimin receptor Virulence LEE Protein 1e-173 99
tir AAY25394.1 translocated intimin receptor Virulence LEE Protein 3e-173 99
tir AAC38390.1 Tir Virulence LEE Protein 4e-148 84
unnamed AAL06376.1 translocated intimin receptor Tir Virulence LEE Protein 6e-125 73
tir CAI43867.1 translocated intimin receptor Not tested LEE Protein 6e-95 63
tir YP_003223468.1 translocated intimin receptor Tir Virulence LEE Protein 8e-95 63
tir AAK26722.1 Tir Virulence LEE Protein 3e-97 63
tir YP_003232160.1 translocated intimin receptor Tir Virulence LEE Protein 4e-97 63
tir AAL57549.1 Tir Virulence LEE Protein 3e-97 63
espE CAC81869.1 EspE protein Virulence LEE II Protein 3e-97 63
tir AAY25391.1 translocated intimin receptor Virulence LEE Protein 5e-84 60
tir AAY25390.1 translocated intimin receptor Virulence LEE Protein 5e-84 60
ECs4561 NP_312588.1 hypothetical protein Virulence LEE Protein 1e-83 59
tir AAC31506.1 L0027 Virulence LEE Protein 1e-83 59
tir AAY25392.1 translocated intimin receptor Virulence LEE Protein 1e-83 59
tir ACU09451.1 translocated intimin receptor protein Tir Virulence LEE Protein 1e-83 59
tir NP_290261.1 translocated intimin receptor protein Not tested LEE Protein 1e-83 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tir YP_003236081.1 putative translocated intimin receptor Tir VFG0737 Protein 2e-148 84
tir YP_003236081.1 putative translocated intimin receptor Tir VFG0805 Protein 6e-84 59