Gene Information

Name : tir (ECO26_5278)
Accession : YP_003232160.1
Strain : Escherichia coli 11368
Genome accession: NC_013361
Putative virulence/resistance : Virulence
Product : translocated intimin receptor Tir
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5352385 - 5354001 bp
Length : 1617 bp
Strand : +
Note : Integrative element ECO26_IE08

DNA sequence :
ATGCCTATTGGTAATCTTGGCCACAATCCCAATGTGAGAGCTTTAATTCCACCTGCACCGCCATTACCTTCACAAACCGA
CGGTGCAGGAGGTGCCCGTAATCAGCTCATTAACTCAAATGGCCCGATGGGGTCTCGTTTGCTATTTACGCCTATAAGGA
ATTCTGTTGCTGATGCTGCTGATTCTCGTGCCAGTGATATTCCCGGACTTCCTACAAATCCACTGCGCTTTGCTGCGTCC
GAGGTATCTTTGCATGGTGCGCTTGAAGTTCTTCATGATAAAGGGGGGCTTGATACTCTTAACTCTGCTATTGGATCTTC
GTTATTCCGTGTTGAAACTCGGGATGATGGCAGCCATGTTGCTATCGGGCAAAAAAATGGCCTCGAGACCACTGTTGTTT
TAAGTGAGCAAGAGTTTTCTAGCTTACAGTCCCTTGATCCTGAAGGTAAAAACAAATTTGTATTTACTGGAGGCCGCGGT
GGCGCAGGGCATGCTATGGTCACGGTTGCTTCAGATATCGCCGAAGCCCGTCAGAGGATAATAGATAAATTAGAACCAAA
GGATACAAAGGAGACGAAGGAGCCAGGGGATCCAAATAGTGGCGAGGGAAAAATCATTGAAATTCATACCTCAACCTCAA
CTTCTAGCCTCCGTGCAGATCCTAAACTTTGGTTGTCATTGGGGACTATTGCTGCAGGTCTGATAGGGATGGCTGCGACG
GGGATTGCACAGGCTGTTGCGTTGACTCCAGAGCCGGATGACCCAATCACTACCGACCCTGATGCTGCAGCAAACACAGC
TGAAGCAGCGGCAAAAGATCAGTTAACGAAAGAAGCATTCCAGAACCCAGATAACCAGAAAGTTAATATCGATGAGAACG
GAAATGCAATTCCGTCCGGGGAACTAAAAGATGATGTTGTTGCGCAAATAGCAGAACAAGCTAAAGCGGCGGGTGAACAG
GCCAGACAGGAAGCTATTGAAAGTAATTCTCAGGCGCAGCAAAAATATGATGAACAGCATGCTAAACGCGAACAGGAAAT
GTCTCTTTCATCGGGGGTTGGCTACGGTATTAGTGGTGCGCTGATTCTTGGCGGGGGAATTGGTGCCGGTGTTACTGCTG
CTCTTCATCGGAAAAACCAACCGGCAGAACAAACAATCACTACACGTACGGTAGTCGATAATCAGCCTACGAATAACGCA
TCTGCGCAGGGCAATACTGACACAAGTGGGCCAGAAGAGTCCCCGGCGAGCAGACGTAATTCGAATGCCAGCCTCGCATC
GAACGGGTCTGACACCTCCAGCACGGGCACGGTAGAGAATCCGTATGCTGACGTTGGAATGCCCAGAAATGATTCACTGG
CTCGCATTTCAGAGGAACCTATTTATGATGAGGTCGCTGCAGATCCTAATTATAGCGTCATTCAACATTTTTCAGGGAAC
AGCCCAGTTACCGGAAGGTTAGTGGGAACCCCAGGGCAAGGTATCCAAAGTACTTATGCGCTTCTGGCAAGCAGCGGCGG
ATTGCGTTTAGGTATGGGAGGATTAACGGGGGGGGGCGAGAGCGCAGTAAGTACTGCCAATGCCGCACCAACGCCGGGAC
CCGCACGTTTCGTTTAA

Protein sequence :
MPIGNLGHNPNVRALIPPAPPLPSQTDGAGGARNQLINSNGPMGSRLLFTPIRNSVADAADSRASDIPGLPTNPLRFAAS
EVSLHGALEVLHDKGGLDTLNSAIGSSLFRVETRDDGSHVAIGQKNGLETTVVLSEQEFSSLQSLDPEGKNKFVFTGGRG
GAGHAMVTVASDIAEARQRIIDKLEPKDTKETKEPGDPNSGEGKIIEIHTSTSTSSLRADPKLWLSLGTIAAGLIGMAAT
GIAQAVALTPEPDDPITTDPDAAANTAEAAAKDQLTKEAFQNPDNQKVNIDENGNAIPSGELKDDVVAQIAEQAKAAGEQ
ARQEAIESNSQAQQKYDEQHAKREQEMSLSSGVGYGISGALILGGGIGAGVTAALHRKNQPAEQTITTRTVVDNQPTNNA
SAQGNTDTSGPEESPASRRNSNASLASNGSDTSSTGTVENPYADVGMPRNDSLARISEEPIYDEVAADPNYSVIQHFSGN
SPVTGRLVGTPGQGIQSTYALLASSGGLRLGMGGLTGGGESAVSTANAAPTPGPARFV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
espE CAC81869.1 EspE protein Virulence LEE II Protein 2e-180 100
tir YP_003232160.1 translocated intimin receptor Tir Virulence LEE Protein 2e-180 100
tir AAK26722.1 Tir Virulence LEE Protein 5e-180 99
tir AAL57549.1 Tir Virulence LEE Protein 5e-180 99
tir CAI43867.1 translocated intimin receptor Not tested LEE Protein 5e-177 98
tir YP_003223468.1 translocated intimin receptor Tir Virulence LEE Protein 7e-177 98
unnamed AAL06376.1 translocated intimin receptor Tir Virulence LEE Protein 7e-106 68
tir AAC38390.1 Tir Virulence LEE Protein 5e-105 67
tir ACU09451.1 translocated intimin receptor protein Tir Virulence LEE Protein 1e-115 66
tir NP_290261.1 translocated intimin receptor protein Not tested LEE Protein 2e-115 66
ECs4561 NP_312588.1 hypothetical protein Virulence LEE Protein 2e-115 66
tir AAC31506.1 L0027 Virulence LEE Protein 1e-115 66
tir AAY25392.1 translocated intimin receptor Virulence LEE Protein 1e-115 66
tir AAY25390.1 translocated intimin receptor Virulence LEE Protein 3e-115 65
tir AAY25391.1 translocated intimin receptor Virulence LEE Protein 3e-115 65
tir YP_003236081.1 putative translocated intimin receptor Tir Not tested LEE Protein 1e-94 63
tir AAY25395.1 translocated intimin receptor Virulence LEE Protein 3e-94 63
tir AAY25394.1 translocated intimin receptor Virulence LEE Protein 2e-94 63
tir AAY25393.1 translocated intimin receptor Virulence LEE Protein 3e-94 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tir YP_003232160.1 translocated intimin receptor Tir VFG0737 Protein 3e-105 67
tir YP_003232160.1 translocated intimin receptor Tir VFG0805 Protein 8e-116 66