Gene Information

Name : escN (ECO26_5271)
Accession : YP_003232153.1
Strain : Escherichia coli 11368
Genome accession: NC_013361
Putative virulence/resistance : Virulence
Product : T3SS structure protein EscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 5346943 - 5348283 bp
Length : 1341 bp
Strand : +
Note : Integrative element ECO26_IE08

DNA sequence :
ATGATTTTAGAGCATGATTCTGTATTGGAAAGATACCCACGTATCCAGAAAGTGCTCAATAGCACTGTGCCGACATTATC
ATTAAATTCGTCTACCAGATATGAAGGCAAGATTACCAATATCGGCGGGACGATTATCAAGGCGCGTTTACCAAAAGCGC
GTATTGGTGCCTTTTACAAGATAGAACCCAGTCAACGTTTAGCTGAGGTGATCGCTATTGATGAAGATGAGGTTTTCCTG
CTGCCTTTTGAGCATATTTCCGGCATGTATTGTGGCCAGTGGCTAAGTTATCAGGGGGAAGAGTTCAAGATTCGTGTTGG
GGACGAACTCCTTGGGCGACTGGTTGATGGTATAGGCAGACCAATGGGGAGCAATATTACTGCACCTTATCTTCCGTTTG
AACGCAGTTTGTATGCTGAACCCCCCGATCCTTTATTAAGGCAGGTTATTGATCAGCCATTTACGCTTGGCGTCAGGGCA
ATAGATGGTTTACTTACTTGCGGTATTGGGCAACGCATCGGTATTTTCGCGGGGTCCGGCGTTGGTAAAAGTACGCTTTT
GGGAATGATTTGTAATGGCGCATCCGCGGATATTATTGTCCTTGCCCTTATCGGCGAGCGTGGTCGCGAAGTAAATGAAT
TCCTCGCGCTTTTACCTCAATCCACGCTTTCTAAATGTGTACTGGTCGTCACAACGTCAGACCGTCCCGCGCTGGAAAGA
ATGAAGGCCGCATTTACGGCGACAACCATTGCAGAGTTCTTCCGGGATCAGGGCAAAAATGTATTATTAATGATGGATTC
CGTAACTCGTTATGCCCGAGCCGCGCGTGATGTTGGGCTTGCATCGGGAGAGCCTGATGTAAGAGGGGGATTCCCTCCGA
GTGTTTTTGCCTCGTTACCCAAATTATTAGAGCGTGCGGGACCTGCGCCAAAAGGTTCAATAACTGCGATTTATACGGTG
CTGTTAGAAAGCGATAATGTGAATGATCCCATCGGTGATGAAGTTCGCTCTATTCTTGATGGACATATTGTGCTTACCCG
AGAACTTGCAGAGGAAAACCATTTCCCTGCAATTGATATTGGTTTAAGCGCCAGTCGTGTTATGCATAACGTTGTTAAAT
CGGAACATTTACGTGCAGCGGCTGAATGCAAAAAGCTTATTGCAACCTATAAGAATATTGAACTGCTTATTCGTATTGGT
GAGTACACGATGGGGCAAGATCCTGAAGCGGATAAGGCAATAAAAAACAGGAAAGCAATTCAGAGCTTTATACAACAAAG
CACCAAAGATATCAGTAGTTACGAAAAAACGATTGAAAGCCTATTCAAAGTGGTTGCCTGA

Protein sequence :
MILEHDSVLERYPRIQKVLNSTVPTLSLNSSTRYEGKITNIGGTIIKARLPKARIGAFYKIEPSQRLAEVIAIDEDEVFL
LPFEHISGMYCGQWLSYQGEEFKIRVGDELLGRLVDGIGRPMGSNITAPYLPFERSLYAEPPDPLLRQVIDQPFTLGVRA
IDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALLPQSTLSKCVLVVTTSDRPALER
MKAAFTATTIAEFFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFASLPKLLERAGPAPKGSITAIYTV
LLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVKSEHLRAAAECKKLIATYKNIELLIRIG
EYTMGQDPEADKAIKNRKAIQSFIQQSTKDISSYEKTIESLFKVVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 0.0 100
escN AAL57542.1 EscN Virulence LEE Protein 0.0 99
escN CAC81862.1 EscN protein Virulence LEE II Protein 0.0 99
escN YP_003223475.1 translocator EscN Virulence LEE Protein 0.0 99
escN CAI43874.1 EscN protein Virulence LEE Protein 0.0 99
escN AAK26715.1 EscN Virulence LEE Protein 0.0 99
escN NP_290268.1 hypothetical protein Virulence LEE Protein 0.0 97
ECs4568 NP_312595.1 EscN Virulence LEE Protein 0.0 97
escN YP_003236088.1 translocator EscN Virulence LEE Protein 0.0 97
escN AAC38383.1 EscN Virulence LEE Protein 0.0 97
escN AAC31513.1 L0034 Virulence LEE Protein 0.0 97
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 0.0 97
unnamed AAL06369.1 EscN Virulence LEE Protein 0.0 95
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-155 77
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-155 77
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-84 52
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-85 51
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-85 51
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-85 51
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-85 51
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-85 51
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-94 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-77 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-78 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-79 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-77 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 7e-79 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 5e-79 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 5e-79 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-75 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-75 49
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-66 48
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 7e-66 48
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-66 48
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-66 48
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 7e-63 48
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-74 47
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 7e-74 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 6e-74 47
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-76 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 9e-70 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 9e-70 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 9e-65 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 5e-70 46
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-62 46
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-64 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-68 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 6e-65 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 6e-65 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-68 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
escN YP_003232153.1 T3SS structure protein EscN VFG0812 Protein 0.0 97
escN YP_003232153.1 T3SS structure protein EscN VFG0730 Protein 0.0 97
escN YP_003232153.1 T3SS structure protein EscN VFG0390 Protein 7e-88 52
escN YP_003232153.1 T3SS structure protein EscN VFG0515 Protein 3e-85 51
escN YP_003232153.1 T3SS structure protein EscN VFG0192 Protein 2e-88 51
escN YP_003232153.1 T3SS structure protein EscN VFG0048 Protein 5e-84 50
escN YP_003232153.1 T3SS structure protein EscN VFG1778 Protein 4e-65 50
escN YP_003232153.1 T3SS structure protein EscN VFG2144 Protein 2e-79 49
escN YP_003232153.1 T3SS structure protein EscN VFG0555 Protein 3e-66 48
escN YP_003232153.1 T3SS structure protein EscN VFG1254 Protein 3e-71 47
escN YP_003232153.1 T3SS structure protein EscN VFG2499 Protein 5e-70 46
escN YP_003232153.1 T3SS structure protein EscN VFG2459 Protein 7e-63 45
escN YP_003232153.1 T3SS structure protein EscN VFG2331 Protein 1e-68 45
escN YP_003232153.1 T3SS structure protein EscN VFG1008 Protein 1e-58 44