Gene Information

Name : escU (ECO26_5259)
Accession : YP_003232141.1
Strain : Escherichia coli 11368
Genome accession: NC_013361
Putative virulence/resistance : Virulence
Product : secretion system apparatus protein SsaU
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4792
EC number : -
Position : 5337674 - 5338711 bp
Length : 1038 bp
Strand : +
Note : member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli

DNA sequence :
ATGAGTGAAAAAACAGAAAAGCCCACACCCAAAAAACTAAGGGATCTAAAAAAGAAGGGCGATGTAACAAAAAGTGAAGA
GGTAATGGCTGCAGTGCAGTCATTAATCTTATTTTCATTTTTTTCTTTATATGGTGCGAGTTTTTTCGTTGAGGTTGTTG
AGTTAGTTAATACGACTATAGACTCGCTAAATAGACCGTTTTTGTATGCCATTCGTGAAATATTAGGTGCGGTATTAAAC
ATATTTTTATTGTATATTTTGCCAATTTCTTTGATTGTCTTTGTTGGAACTGTTACAACTGGTGTATCACAAACAGGATT
CATCTTTGCGGTTGAAAAAATAAAACCATCGGCTCAGAAGATTAGTGTAAAAAATAACCTGAAAAATATTTTTTCTGTAA
AGAGTATTTTTGAGCTGCTTAAGTCAGTATTTAAGTTAGTGATAATTACTCTCATTTTTTACTTTATGGGGCATTCATAT
GCAAATGAGTTTGCAAATTTCACAAGACTGAACGCATATCAAACTCTTGTCGTTGTTGCCTTTTTTGTTTTTCTTTTATG
GAAAGGCGTGTTATTCGGATATCTACTCTTTTCAGTATTTGATTTCTGGTTCCAGAAGCATGAGGGACTGAAGAAAATGA
AAATGAGTAAAGATGAGGTGAAACGAGAAGCCAAGGATACTGATGGTAACCCTGAAATTAAAGGGGAGCGCCGTCGCCTT
CATTCTGAGATACAAAGTGGAAGTCTGGCTAATAACATCAAAAAATCAACCGTGATCGTCAAAAACCCGACTCACATTGC
GATTTGCCTATACTATAAACTCGGGGAGACTCCATTGCCTTTAGTTATTGAAACAGGAAAAGATGCCAAAGCTCTACAGA
TCATTAAACTGGCTGAACTCTATGATATTCCAGTGATTGAAGATATTACTTTGGCAAGAAGTCTTTATAAGAACATACAT
AAAGGACAATACATAACAGAAGACTTTTTTGAACCTGTAGCACAATTGATTCGTATAGCAATAGATCTTGATTATTAA

Protein sequence :
MSEKTEKPTPKKLRDLKKKGDVTKSEEVMAAVQSLILFSFFSLYGASFFVEVVELVNTTIDSLNRPFLYAIREILGAVLN
IFLLYILPISLIVFVGTVTTGVSQTGFIFAVEKIKPSAQKISVKNNLKNIFSVKSIFELLKSVFKLVIITLIFYFMGHSY
ANEFANFTRLNAYQTLVVVAFFVFLLWKGVLFGYLLFSVFDFWFQKHEGLKKMKMSKDEVKREAKDTDGNPEIKGERRRL
HSEIQSGSLANNIKKSTVIVKNPTHIAICLYYKLGETPLPLVIETGKDAKALQIIKLAELYDIPVIEDITLARSLYKNIH
KGQYITEDFFEPVAQLIRIAIDLDY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escU CAC81850.1 EscU protein Virulence LEE II Protein 3e-144 100
escU YP_003232141.1 secretion system apparatus protein SsaU Virulence LEE Protein 5e-144 100
escU CAI43886.1 EscU protein Virulence LEE Protein 9e-144 99
escU AAK26703.1 EscU Virulence LEE Protein 9e-144 99
escU YP_003223487.1 T3SS structure protein EscU Virulence LEE Protein 1e-143 99
escU AAL57530.1 EscU Virulence LEE Protein 9e-144 99
escU AAC31525.1 L0046 Virulence LEE Protein 2e-141 98
escU NP_290280.1 secretion system apparatus protein SsaU Virulence LEE Protein 3e-141 98
escU ACU09470.1 secretion system apparatus protein SsaU Virulence LEE Protein 2e-141 98
ECs4580 NP_312607.1 secretion system apparatus protein SsaU Virulence LEE Protein 3e-141 98
escU AAC38372.1 EscU Virulence LEE Protein 2e-141 98
escU YP_003236100.1 T3SS structure protein EscU Virulence LEE Protein 2e-141 98
unnamed AAL06357.1 EscU Virulence LEE Protein 7e-137 92
escU AFO66307.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-113 75
escU AFO66403.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-113 75
YPO0273 YP_002345355.1 secretion system apparatus protein SsaU Virulence Not named Protein 6e-58 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
escU YP_003232141.1 secretion system apparatus protein SsaU VFG0718 Protein 1e-141 98
escU YP_003232141.1 secretion system apparatus protein SsaU VFG0824 Protein 1e-141 98