Gene Information

Name : ECO26_4071 (ECO26_4071)
Accession : YP_003230995.1
Strain : Escherichia coli 11368
Genome accession: NC_013361
Putative virulence/resistance : Virulence
Product : bifunctional enterobactin receptor/adhesin protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG4771
EC number : -
Position : 4032151 - 4034241 bp
Length : 2091 bp
Strand : +
Note : IrgAue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor

DNA sequence :
ATGCGAATAACCACTCTGGCTTCCGTAGTCATTCCCTGTCTCGGATTTTCAGCCAGCAGCATAGCTGCTGCAGAGGATGT
GATGATTGTCTCGGCATCCGGCTATGAGAAAAAGCTGACTAACGCAGCCGCCAGTGTTTCTGTGATTAGCCAAGAGGAAT
TGCAGTCCAGCCAGTACCACGATCTGGCGGAGGCTCTGAGATCAGTAGAGGGTGTGGATGTTGAAAGTGGTACGGGTAAA
ACCGGTGGGCTGGAAATCAGCATCCGAGGAATGCCAGCCAGTTACACGCTGATACTGATTGATGGTGTTCGTCAGGGCGG
AAGCAGTGACGTGACTCCCAACGGTTTTTCTGCCATGAATACCGGGTTCATGCCCCCTCTGGCCGCCATTGAGCGTATTG
AGGTTATCAGGGGGCCGATGTCCACACTGTATGGCTCTGATGCGATGGGCGGTGTGGTGAATATCATTACCAGAAAGAAT
GCAGACAAATGGCTCTCTTCCGTCAATGCAGGGCTGAATCTGCAGGAAAGCAACAAATGGGGTAACAGCAGCCAGTTTAA
TTTCTGGAGCAGTGGTCCCCTTGTGGATGATTCTGTCAGCCTGCAGGTACGCGGTAGCACACAACAGCGTCAGGGCTCAT
CGGTCACATCACTGAGCGATACAGCAGCCACGCGTATTCCTTATCCCACGGAGTCACAGAATTATAATCTTGGTGCACGT
CTTGACTGGAAGGCGTCGGAGCAGGATGTGCTCTGGTTTGATATGGATACCACCCGGCAGCGTTATGATAACCGGGATGG
GCAACTGGGGAGTCTGACGGGGGGATATGACCGGACCCTGCGCTATGAGCGAAACAAAATTTCAGCTGGCTATGATCATA
CTTTCACCTTCGGAACATGGAAATCGTATCTGAACTGGAACGAGACGGAAAATAAAGGTCGTGAGCTTGTACGCAATGTA
CTGAAACGCGACAAATGGGGCCTTGCCGGTCAACTGCGGGAGCTTAAGGAATCTAACCTTATCCTGAATTCATTGCTGCT
TACCCCTCTGGGAGAATCTCATCTGGTTACTGTGGGGGGCGAGTATCAGAGTTCGTCCATGAAAGATGGGGTTGTCCTTG
CCAGCACAGGTGAAACTTTCCGGCAGAAAAGCTGGTCGGTATTTGCTGAGGACGAGTGGCATCTCACGGATGCACTTGCG
CTGACTGCGGGCAGCCGCTATGAACATCATGAGCAATTCGGGGGGCACTTCAGTCCGCGTGCATATCTGGTCTGGGATGT
GGCAGATGCCTGGACGCTGAAAGGCGGTGTGACCACGGGATATAAGGCACCCAGAATGGGGCAGCTCCATAAAGGGATTA
GTGGTGTGTCCGGGCAGGGAAAAACAAATCTACTTGGTAACCCCGACCTGAAGCCGGAAGAGAGCGTCAGTTATGAGGCT
GGGGTGTATTACGATAACCCCGCCGGTCTGAACGCCAATATCACAGGTTTTATGACTGACTTCTCTAACAAGATTGTCTC
TTATTCCATAAATGATAACACCAATAGCTATATAAACAGCGGAAAGGCCCGGTTGCACGGTGTGGAATTTGCCGGCACAT
TGCCGCTATGGTCAGAGGATGTCACGCTGTCGCTGAATTACACCTGGACCCGAAGTGAACAACGTGATGGTGATAATAAA
GGTGCACCGCTGAGTTATACCCCAGAACACATGGTGAATGCGAAACTGAACTGGCAGATCACCGAAGAGGTGGCATCATG
GCTGGGTGCCCGTTATCGCGGGAAAACACCACGTTTCACCCAGAATTATTCGTCGCTGAGCGCTGTACAGAAGAAAGTAT
ATGATGAGAAAGGAGAATACCTGAAAGCCTGGACGGTGGTGGATGCAGGTCTGTCGTGGAAGGTGACGGATGCCCTGACG
CTGAATGCGGCAGTGAATAACCTGCTCAACAAGGATTACAGTGACGTGAGTCTGTACAGTGCCGGTAAGAGTACGCTTTA
TGCCGGTGATTACTTCCAGACGGGATCATCAACAACGGGATATGTGATACCTGAGCGAAATTACTGGATGTCGCTGAACT
ATCAGTTCTGA

Protein sequence :
MRITTLASVVIPCLGFSASSIAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRSVEGVDVESGTGK
TGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN
ADKWLSSVNAGLNLQESNKWGNSSQFNFWSSGPLVDDSVSLQVRGSTQQRQGSSVTSLSDTAATRIPYPTESQNYNLGAR
LDWKASEQDVLWFDMDTTRQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHTFTFGTWKSYLNWNETENKGRELVRNV
LKRDKWGLAGQLRELKESNLILNSLLLTPLGESHLVTVGGEYQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALA
LTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLHKGISGVSGQGKTNLLGNPDLKPEESVSYEA
GVYYDNPAGLNANITGFMTDFSNKIVSYSINDNTNSYINSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNK
GAPLSYTPEHMVNAKLNWQITEEVASWLGARYRGKTPRFTQNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKVTDALT
LNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3610 NP_755485.1 bifunctional enterobactin receptor/adhesin protein Not tested PAI I CFT073 Protein 0.0 99
ECUMN_3356 YP_002414032.1 bifunctional enterobactin receptor/adhesin protein Virulence Not named Protein 0.0 99
Z1178 NP_286713.1 bifunctional enterobactin receptor/adhesin protein Virulence TAI Protein 0.0 99
Z1617 NP_287121.1 bifunctional enterobactin receptor/adhesin protein Not tested TAI Protein 0.0 99
r4 AAC61730.1 exogenous ferric siderophore receptor R4 Not tested PAI I CFT073 Protein 0.0 99
iha AAF36432.2 adhesin Virulence TAI Protein 0.0 99
unnamed CAC39288.1 hypothetical protein Not tested LPA Protein 0.0 96

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECO26_4071 YP_003230995.1 bifunctional enterobactin receptor/adhesin protein VFG1731 Protein 0.0 99