Gene Information

Name : ureB (ECO26_1281)
Accession : YP_003228330.1
Strain : Escherichia coli 11368
Genome accession: NC_013361
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0832
EC number : -
Position : 1312171 - 1312491 bp
Length : 321 bp
Strand : +
Note : ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzym

DNA sequence :
ATGATCCCTGGAGAATATAAGGTTAAACCTGGCTATATAGAGCTTAACATCGGCCGGGCTACCTGCAGTATTATCGTTGA
AAATCACGGAGACCGACCAATTCAGGTCGGTTCCCATTATCACTTCGCGGAGGTTAACCCGGCACTGAAGTTCGATCGCC
AGAAGGCAAGAGGCTATCGTCTCAATATCGCCGCCGGAACTGCAGTGCGCTTCGAACCAGGCCAAAAGCGTGAGGTTGAT
CTGGTGGCGCTGAGCGGTGCCCGTATCGTGCACGGTTTCCGCGGAGATATAATGGGTGAGCTGGAGGCAAATGATGAGTA
A

Protein sequence :
MIPGEYKVKPGYIELNIGRATCSIIVENHGDRPIQVGSHYHFAEVNPALKFDRQKARGYRLNIAAGTAVRFEPGQKREVD
LVALSGARIVHGFRGDIMGELEANDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureB NP_286679.1 urease subunit beta Virulence TAI Protein 4e-46 99
ureB NP_287087.1 urease subunit beta Not tested TAI Protein 4e-46 99
ureB YP_003784326.1 urease subunit beta Not tested PiCp 7 Protein 4e-22 54
ureB YP_005682175.1 Urease beta subunit Not tested PiCp 7 Protein 3e-22 54
ureB YP_005684267.1 Urease beta subunit Not tested PiCp 7 Protein 3e-22 54
ureB YP_005686359.1 Urease beta subunit Not tested PiCp 7 Protein 3e-22 54