Gene Information

Name : guaA (Za10_0073)
Accession : YP_003225211.1
Strain : Zymomonas mobilis NCIMB 11163
Genome accession: NC_013355
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 82010 - 83590 bp
Length : 1581 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCCGTTTCTTCAATCGCCGATAAAATTGTTTCTGAATCGATTCTCATTGTCGATTTCGGAAGCCAAGTCACCCAGCT
TATCGCTCGCCGTGTCCGTGAAGCCGGTGTATATAGCGAAATCGTCCCTTTTAACCGTGCAGAAGAAGCCTTTCAGCGCT
TGCAGCCAAAAGGTATTATCCTTTCGGGTAGTCCGGCTTCTGTTGTCGCAGAAGGCAGTCCGAGAGCGCCAGAATCCTTC
TTTCAGGCAGGTATTCCGATTTTCGGCATCTGCTATGGGCAGCAGGTTATGTGCCATCAATTGGGCGGCAAAGTTACCGC
CAATGATGTTGATGGCGAATTTGGCCGTGCCTTTATTGATGTAATCGCCCCCTCGCCTCTGTTTGAAAATTTGTGGAAGG
TCGGCGAAAAGCATCAGGTATGGATGAGCCATGCCGATCGGGTCGAGGCTTTGCCTGAAGGCTTTAAGCCTATTGCGGTT
TCTGATGGTGCGCCTTTCGCTTTGATCGCTGATGAAAAGCGCCGTTTCTATGGCATGCAATTTCATCCTGAAGTGGTGCA
TACCCCTGATGGAGGTAAGCTGATCGCTCATTTTGTCCATGACATCTGCGGTTTGGCCGGTGATTGGACGATGGCGGAAT
TTCGTCAGACAAAAATTGCTGAAATCCGCAAACAAGTCGGCGATGGTCGTGTTATTTGCGGCTTGTCTGGTGGTGTTGAT
TCTTCTGTGACTGCCGTTTTGGTGCATGAAGCTATTGGCGACCAGTTGACTTGTGTTTTTGTCGATCATGGTTTGATGCG
TCAGGGCGAAGCCGAGCAGGTCGTTTCCCTGTTCCGTGAGCATTATGGTATCAAACTGGTTCACGTGAATGCTGAAGACC
GCTTTTTGGCTGGTTTAAAGGGCGTAACTGACCCTGAAACTAAGCGGAAATTCATCGGCAAAACTTTTATCGAAATTTTT
GAAGAAGAAGCCAAGAAAATCGGTGGTGCCGACTTCCTTGCTCAAGGCACGCTTTATCCTGATGTGATCGAAAGCGTGAG
CTTCCTTGGAGGCCCTTCGGTAACGATTAAAAGCCATCATAATGTTGGTGGCTTGCCGGAACGCATGAATATGAAGCTGG
TCGAGCCGCTTCGTGAATTGTTCAAGGATGAAGTCCGCGATTTAGGGCGCGAATTGGGAATGCCTGACATCTTCGTCGAT
CGTCATCCCTTCCCAGGTCCTGGTCTGGCTATCCGTATTCCGGGCGAAGTGACCAAGGAACGCTGCGATATTCTCCGAAA
AGCAGACGCGGTCTATCTCGAAGAAATCCGTAACGCCGGTTTGTATAATGCGATTTGGCAGGCTTTTGCGGTATTGTTAC
CTGTCAGAACCGTTGGTGTGATGGGTGACGGCAGAACTTACGATTCTGTTTGCGCCTTGCGAGCGGTGACTTCGACCGAC
GGAATGACCGCTGAAATCTATCCTTTCCAGCCGGAATTTCTCGCCAATGTCGCCACCCGTATTGTGAATGAGGTCAGGGG
CATTAACCGTGTGACCTATGATTTCACCTCTAAGCCACCCGGAACGATTGAATGGGAATAG

Protein sequence :
MSVSSIADKIVSESILIVDFGSQVTQLIARRVREAGVYSEIVPFNRAEEAFQRLQPKGIILSGSPASVVAEGSPRAPESF
FQAGIPIFGICYGQQVMCHQLGGKVTANDVDGEFGRAFIDVIAPSPLFENLWKVGEKHQVWMSHADRVEALPEGFKPIAV
SDGAPFALIADEKRRFYGMQFHPEVVHTPDGGKLIAHFVHDICGLAGDWTMAEFRQTKIAEIRKQVGDGRVICGLSGGVD
SSVTAVLVHEAIGDQLTCVFVDHGLMRQGEAEQVVSLFREHYGIKLVHVNAEDRFLAGLKGVTDPETKRKFIGKTFIEIF
EEEAKKIGGADFLAQGTLYPDVIESVSFLGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRDLGRELGMPDIFVD
RHPFPGPGLAIRIPGEVTKERCDILRKADAVYLEEIRNAGLYNAIWQAFAVLLPVRTVGVMGDGRTYDSVCALRAVTSTD
GMTAEIYPFQPEFLANVATRIVNEVRGINRVTYDFTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-128 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-127 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-127 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-116 52