Gene Information

Name : ECO103_5061 (ECO103_5061)
Accession : YP_003224874.1
Strain : Escherichia coli 12009
Genome accession: NC_013353
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 5256863 - 5258107 bp
Length : 1245 bp
Strand : +
Note : Integrative element ECO103_IE06

DNA sequence : 
ATGGCTCTAACAGATATCAAAGTCAGAACAGCCAAGCCAACGGATAAGCAATATAAGCTGACCGATGGCAACGGTATGCA
CCTTCTTGTTCATCCAAATGGCTCTAAGTACTGGCGTCTGCAGTACCGATTTGGCGGAAAGCAAAAGATGCTGGCTCTGG
GTGTTTACCCTGACGTATCTCTTGCAGATGCCAGAGCTCGTCGCGATGACGCTCGTAAGCTTTTAGCAAACGGCATCGAT
CCGGGAGATAAAAAGAAAAATGATAAGATTGAGCAGGAGGAAGCACGTACTTTTGAGCAGCTTGCTATTGAGTGGCATGC
CACAAATAAAAAGTGGTCGGAAGAACATAGTCGACGAGTGCTTAAAAGCCTGGAGGACAATCTCTTCCCTGCCATAGGTA
AGCGGAATATCGCTGATCTTAAAACTAGAGACCTGCTGGCCCCAATCAAAGCGGTAGAACTGTCAGGACGGCTTGAGGTT
GCTTCACGATTACAACAGCGAACCACGGCAATTATGCGCTATGCCGTACAGAGTGGTTTACTGGACTATAACCCCGCGCA
GGAGATGGTTGGCGCTGTTGCTTCAAATAACAGGCAGCATCGACCTGCTCTTCAGTTGAAGCTAATCCCAGAACTATTAC
GGCGCATAGATAGTTATACCGGTAGACCTCTTACTAGACTTGCCGTCGAACTCACGCTCCTGGTATTCATTCGTTCAAGT
GAACTACGCTTTGCTCGTTGGTCTGAGATCGATTTCGAAACATCAATGTGGACAATACCTGCAGAGCGCGAAGCTATTGA
AGGAGTAAAGCATTCACAGCGTGGTTCAAAAATGCGTACGCCTCATCTGGTGCCGCTTTCTCATCAAGCTTTAGCAATTC
TTAAAGATGTTTACAAACTTAGTGGTGATCGCGATTTTGTTTTCATCGGCGATCATGACCATCGCAAACCGATGAGTGAA
AACACGGTGAACAAGGCGCTGCGCGTTATGGGTTATGACACGAAGGTAGAGGTTTGTGGGCACGGTTTCAGGACAATGGC
CTGTAGTTCATTGATCGAGTCTGGATTGTGGTCGAGGGATGCAGTGGAAAGGCAGATGAGCCATATGGAACGTAGCTCAG
TACGCGCAGCTTACATTCATAAGGCCGAACATCTTGATGAACGGCGACTGATGCTGCAGTGGTGGGCTGATTTTTTGGAT
GCGAATAGGGAAAGCGAAGTTAGCCCTTATGACTTTGGCAAGTAG

Protein sequence : 
MALTDIKVRTAKPTDKQYKLTDGNGMHLLVHPNGSKYWRLQYRFGGKQKMLALGVYPDVSLADARARRDDARKLLANGID
PGDKKKNDKIEQEEARTFEQLAIEWHATNKKWSEEHSRRVLKSLEDNLFPAIGKRNIADLKTRDLLAPIKAVELSGRLEV
ASRLQQRTTAIMRYAVQSGLLDYNPAQEMVGAVASNNRQHRPALQLKLIPELLRRIDSYTGRPLTRLAVELTLLVFIRSS
ELRFARWSEIDFETSMWTIPAEREAIEGVKHSQRGSKMRTPHLVPLSHQALAILKDVYKLSGDRDFVFIGDHDHRKPMSE
NTVNKALRVMGYDTKVEVCGHGFRTMACSSLIESGLWSRDAVERQMSHMERSSVRAAYIHKAEHLDERRLMLQWWADFLD
ANRESEVSPYDFGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 1e-156 84
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 5e-140 68
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 3e-140 68
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 2e-140 68
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 2e-140 68
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 4e-140 68
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 1e-139 68
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-140 68
int AAK16198.1 Int Not tested PAI-I AL862 Protein 9e-140 68
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 9e-140 68
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 8e-139 68
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 6e-139 68
int AAL51003.1 CP4-like integrase Not tested LEE Protein 4e-139 68
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 7e-139 67
int AAK00456.1 Int Not tested SHI-1 Protein 2e-130 67
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 4e-139 67
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 5e-139 67
int AAL51028.1 CP4-like integrase Not tested LEE Protein 4e-139 67
int-phe AAL60261.1 Int-phe Not tested LEE Protein 4e-139 67
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 3e-138 67
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 5e-139 67
int CAC81896.1 integrase Not tested LEE II Protein 7e-129 66
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 1e-125 62
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 1e-125 62
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 3e-114 58
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 6e-82 55
int CAA08754.1 integrase Not tested HPI Protein 3e-111 55
int CAA21384.1 - Not tested HPI Protein 1e-110 55
int CAB59974.1 integrase Not tested HPI Protein 7e-112 55
int YP_002346908.1 integrase Not tested HPI Protein 1e-110 55
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 1e-110 55
int2 NP_993013.1 integrase Not tested HPI Protein 1e-110 55
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 2e-112 55
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 2e-112 55
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 7e-95 55
unnamed AAD17660.1 unknown Not tested HPI Protein 5e-107 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 4e-102 52
int AAD44730.1 Int Not tested SHI-2 Protein 5e-82 45
int CAC39282.1 integrase Not tested LPA Protein 1e-82 45
aec33 AAW51716.1 Int Not tested AGI-3 Protein 1e-82 45
int AAC31482.1 CP4-like integrase Not tested LEE Protein 5e-81 44
int ACU09430.1 integrase Not tested LEE Protein 5e-81 44
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 7e-81 44
ECs4534 NP_312561.1 integrase Not tested LEE Protein 7e-81 44
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 1e-80 44
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 1e-80 44
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 9e-81 44
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 6e-74 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 1e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECO103_5061 YP_003224874.1 integrase VFG1536 Protein 7e-157 84
ECO103_5061 YP_003224874.1 integrase VFG0626 Protein 9e-141 68
ECO103_5061 YP_003224874.1 integrase VFG1693 Protein 1e-140 68
ECO103_5061 YP_003224874.1 integrase VFG0783 Protein 3e-81 44
ECO103_5061 YP_003224874.1 integrase VFG0598 Protein 5e-81 44