Gene Information

Name : tir (ECO103_3611)
Accession : YP_003223468.1
Strain : Escherichia coli 12009
Genome accession: NC_013353
Putative virulence/resistance : Virulence
Product : translocated intimin receptor Tir
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3689885 - 3691501 bp
Length : 1617 bp
Strand : -
Note : Integrative element ECO103_IE03

DNA sequence :
ATGCCTATTGGTAATCTTGGCCACAATCCCAATGTGAGAGCTTTAATTCCACCTGCACCGCCATTACCTTCACAAACCGA
CGGTGCAGGAGGTGCCCGTAATCAGCTCATTAACTCAAATGGCCCGATGGGGTCTCGTTTGCTATTTACGCCTATAAGGA
ATTCTGTTGCTGATGCTGCTGATTCTCGTGCCAGTGATATTCCCGGACTTCCTACAAATCCACTGCGCTTTGCTGCGTCC
GAGGTATCTTTGCATGGTGCGCTTGAAGTTCTTCATGATAAAGGGGGGCTTGATACTCTTAACTCTGCTATTGGATCTTC
GTTATTCCGTGTTGAAACTCGGGATGATGGCAGCCATGTTGCTATCGGGCAAAAAAATGGCCTCGAGACCACTGTTGTTT
TAAGTGATCAAGAGTTTTCTAGCTTACAGTCCCTTGATCCTGAAGGTAAAAACAAATTTGTATTTACTGGAGGCCGCGGT
GGCGCAGGGCATGCTATGGTCACGGTTGCTTCAGATATCGCCGAAGCCCGTCAGAGGATAATAGATAAATTAGAACCAAA
GGATACAAAGGAGACGAAGGAGCCAGGGGATCCAAATAGTGGCGAGGGAAAAATCATTGAAATTCATACCTCAACCTCAA
CTTCTAGCCTCCGTGCAGATCCTAAACTTTGGTTGTCATTGGGGACTATTGCTGCAGGTCTGATAGGGATGGCTGCGACG
GGTATTGCACAGGCTGTTGCGTTGACTCCAGAGCCGGATGATCCAACTACTACCGATCCTGATACTGCAGCAAGCACAGC
TGAAGCTGCGACAAAAGATCGGTTAACGCAGGAGGCATTCCAGGATCCAGATAAACAAAAAGTTAATATCGATGAGAACG
GAAATGCAATTCCGTCAGGGGAATTAATAGATGATGTTGTTGCGCAAATAGCAGAACAAGCTAAAGCGGCGGGGGAACAG
GCCAGACAGGAAGCTATTGAAAGTAATTCTCAGGCGCAGAAAAAATATGATGAGCAGCATGCTAAACGCGAACAGGAAAT
GTCTCTTTCATCGGGGGTTGGCTACGGTATTAGTGGGGCGCTGATTCTTGGCGGGGGAATTGGTGCCGGTGTTACTGCTG
CTCTTCATCGGAAAAACCAACCGGCAGAACAAACAATCACTACACGTACAGTAGTCGATAATCAGCCTACGAATAACGCA
TCTGCACAGGGCAATACTGACACAAGTGGGCCAGAAGAGTCCCCGGCGAGCAGGCGCAATTCGAATGCCAGCCTTGCATC
GAACGGGTCTGATACCTCCAGTACGGGCACGGTAGAGAATCCGTATGCTGACGTTGGAATGCCCAGAAATGATTCACTGG
CTCGTATTCCAGAGGAACCTATTTATGATGAGGTCGCTGCAGATCCTAATTATAGCGTCATTCAACATTTTTCAGGGAAC
AGCCCAGTTACCGGAAGGTTAGTGGGAACCCCAGGGCAAGGCATCCAAAGTACTTATGCGCTTCTGGCAAGCAGCGGCGG
ATTGCGTTTAGGTATGGGAGGATTAACGGGGGGGGGCGAGAGCGCAGTAAGTACTGCCAATGCCTCACCAACGCCGGGAC
CCGCACGTTTCGTTTAA

Protein sequence :
MPIGNLGHNPNVRALIPPAPPLPSQTDGAGGARNQLINSNGPMGSRLLFTPIRNSVADAADSRASDIPGLPTNPLRFAAS
EVSLHGALEVLHDKGGLDTLNSAIGSSLFRVETRDDGSHVAIGQKNGLETTVVLSDQEFSSLQSLDPEGKNKFVFTGGRG
GAGHAMVTVASDIAEARQRIIDKLEPKDTKETKEPGDPNSGEGKIIEIHTSTSTSSLRADPKLWLSLGTIAAGLIGMAAT
GIAQAVALTPEPDDPTTTDPDTAASTAEAATKDRLTQEAFQDPDKQKVNIDENGNAIPSGELIDDVVAQIAEQAKAAGEQ
ARQEAIESNSQAQKKYDEQHAKREQEMSLSSGVGYGISGALILGGGIGAGVTAALHRKNQPAEQTITTRTVVDNQPTNNA
SAQGNTDTSGPEESPASRRNSNASLASNGSDTSSTGTVENPYADVGMPRNDSLARIPEEPIYDEVAADPNYSVIQHFSGN
SPVTGRLVGTPGQGIQSTYALLASSGGLRLGMGGLTGGGESAVSTANASPTPGPARFV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tir CAI43867.1 translocated intimin receptor Not tested LEE Protein 0.0 100
tir YP_003223468.1 translocated intimin receptor Tir Virulence LEE Protein 0.0 100
tir AAL57549.1 Tir Virulence LEE Protein 0.0 98
espE CAC81869.1 EspE protein Virulence LEE II Protein 0.0 98
tir YP_003232160.1 translocated intimin receptor Tir Virulence LEE Protein 0.0 98
tir AAK26722.1 Tir Virulence LEE Protein 0.0 98
unnamed AAL06376.1 translocated intimin receptor Tir Virulence LEE Protein 2e-108 67
tir AAC38390.1 Tir Virulence LEE Protein 3e-109 66
tir NP_290261.1 translocated intimin receptor protein Not tested LEE Protein 4e-120 66
ECs4561 NP_312588.1 hypothetical protein Virulence LEE Protein 4e-120 66
tir AAC31506.1 L0027 Virulence LEE Protein 3e-120 66
tir AAY25392.1 translocated intimin receptor Virulence LEE Protein 3e-120 66
tir ACU09451.1 translocated intimin receptor protein Tir Virulence LEE Protein 3e-120 66
tir AAY25390.1 translocated intimin receptor Virulence LEE Protein 7e-120 65
tir AAY25391.1 translocated intimin receptor Virulence LEE Protein 7e-120 65
tir YP_003236081.1 putative translocated intimin receptor Tir Not tested LEE Protein 9e-98 63
tir AAY25393.1 translocated intimin receptor Virulence LEE Protein 4e-97 63
tir AAY25395.1 translocated intimin receptor Virulence LEE Protein 4e-97 63
tir AAY25394.1 translocated intimin receptor Virulence LEE Protein 3e-97 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tir YP_003223468.1 translocated intimin receptor Tir VFG0737 Protein 2e-109 66
tir YP_003223468.1 translocated intimin receptor Tir VFG0805 Protein 2e-120 66