Gene Information

Name : clpB (CDR20291_1933)
Accession : YP_003218420.1
Strain : Clostridium difficile R20291
Genome accession: NC_013316
Putative virulence/resistance : Virulence
Product : chaperone
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2258208 - 2260802 bp
Length : 2595 bp
Strand : -
Note : -

DNA sequence :
ATGGACGTAGAAAAAATGACTTTAAGAGTTCAAAAAAGTTTAAATGAGGCTTATAACGAAGCAGTAAAAAATCATAACCA
ACAAGTAGATGTAATTCATCTTTTCTCAGCACTTATTAATCAAGAGGATGGATTGATACCAAATATAATCGAAAAAATGA
ATATATCAATTGATTCTTTGAGAAATACTGTAAACTTTGAAATTGATAAGCTTCCAAAAGTATATGGAGAAGGTGCTGAC
TCACAAGGAGTATCAGCTACTAGAAAAATAAATGAGGTGCTTATAAAGGCAGAGAGTATTTCTAAAGAATTTAAAGATTC
ATATATAAGTGTAGAGCATGTTATGCTTGCAATGATGGAAACAGAATCAAAATCAGCTGTTGGTAAAATATTAAAACAAT
ATAATATAAATAAGAATGACTTTTTAAATATTTTATCACAAGTGAGAGGTAGTCAAAGAGTAGAAACACAAGACCCAGAA
GGCACATATGATGCACTTGCTAGATATGGAACAAACTTAGTAGATTTAGCCAAGAAAAATAAATTAGACCCTGTAATTGG
GAGAGATGAAGAAATAAGAAGGATTATAAGAATTTTATCAAGAAGAACAAAAAATAATCCTGTATTGATTGGTGAGCCAG
GTGTAGGTAAAACTGCAATTGTAGAAGGGTTAGCAGAGAGAATAGTAAGAGGAGATGTCCCAGAAGGTTTAAAAGATAAG
ATTGTATTCTCACTTGATATGGGAGCTTTAATTGCTGGTGCAAAATATAGAGGTGAATTTGAAGAAAGATTAAAGGCAGT
TTTAAAAGAAGTTCAAAGTTCTGATGGAAAGATTATACTGTTTATAGATGAGATTCATACTATCGTTGGAGCTGGTAAAA
CAGAAGGTTCAATGGATGCAGGTAATCTTATTAAACCTATGCTTGCAAGAGGTGAATTGAACTGTATTGGTGCAACTACT
TTTGATGAATATAGAAAGTATATAGAAAAAGATAAGGCTCTTGAAAGACGTTTTCAGCCTGTAATTGCAGAAGAACCTAC
TGTTGAAGACACAATATCTATACTTAGAGGTTTAAAAGAAAGATTTGAGATACATCATGGAGTAAGAATACATGATAATG
CTATTGTAGCAGCAGCAAAACTTTCTCATAGATATATACAAGATAGATTTTTACCAGATAAAGCAATTGATTTAATTGAT
GAAGCTGGAGCTATGATTCGTAGTGAAATAGATTCATTGCCAACAGAATTAGATGTTGTTAGAAGAAAGTTATTTACATT
AGAAACTGAAAGAGAAGCATTACTTAAAGAAAATGATGATAAAAGCAAATCAAGATTGGATGATATTCAAAAAGAAATAG
CAGAGTTAAAATCTAAAAATGATGAAATGACAGCAAAATATGAAAAAGAAAAGAGTCAAATATTAGATATTAAAAACTTA
AAGGCTCAATTAGACGAAGCTAAAGGTAAAGCTGAAAAGTATGAAAGAGAATATGATTTCAACAAAGCAGCAGAGGTTAA
ATATGGTGAAATACCTAAGTTAGAAGAACAAATAAAGCAGTACGAAGAAAATATGAATGATGGTTCTGAAAATTCTCTTT
TAAAAGAAGAAGTTACTGAAGAAGAAATATCTAGCATTGTATCAAAGTGGACAGGTATACCAGTAACTAAACTAGTTGAA
GGAGAAAGAGAAAAATTACTTAAACTAGAAGATGAACTTCATAAAAGAGTTATTGGACAAGATGAAGCAGTTACAGCAGT
TTCAAATGCAGTAATACGTGCAAGAGCAGGATTAAAAGATGAAAGAAAACCAATTGGTTCATTTATTTTCTTAGGCCCTA
CAGGTGTTGGTAAAACTGAACTTGCAAAAACTCTTGCTAGAAATTTATTCGATAGTGACGATAATATAATAAGAATAGAT
ATGTCTGAATACATGGAAAAACATGCTGTATCAAGACTAGTTGGACCTCCTCCAGGGTACGTGGGATATGAAGAGGGTGG
TCAACTTACAGAAGCAGTTAGACGTGCTCCTTATTCTGTAATACTATTTGATGAGATAGAAAAAGCACATGAGGATGTAT
TTAACATGTTCTTACAGATATTAGATGATGGTAGACTTACTGATAATAAAGGTAAGACAGTAGACTTTAAAAATACTCTT
ATAATAATGACTTCTAATATAGGAAGTAATTATCTATTAGAAGCAGGAGGAAATATAACAGAGACTACTAACAATTTAGT
AATGAATGAAATGAAGCATAGATTTAAACCTGAGTTTTTAAACAGAGTAGATGATATTATAATGTTTAAGCCTTTAGACC
AAGAAAATATCAAGAAAATTATAGATATATTTATGAAAGATTTAAAAAATAGATTAAAAGAAAAAGATATTACTATTGAA
GTTACAAATTCAGCAAAAGATGTTATGGTGAGAGAAGGATATGACCCTGTATATGGAGCAAGACCTCTTAAGAGATATAT
AGGAAATACATTAGAAACTATAATTGCAAAGAAACTTATTGCTGGAGATGTGTATAATGGATGTACTATAGTTATAGATG
GAAAAGATGAAAATATTGAAGTTTTAGTTAAATAA

Protein sequence :
MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDGLIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGAD
SQGVSATRKINEVLIKAESISKEFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKTAIVEGLAERIVRGDVPEGLKDK
IVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDGKIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATT
FDEYRKYIEKDKALERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLPDKAIDLID
EAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQKEIAELKSKNDEMTAKYEKEKSQILDIKNL
KAQLDEAKGKAEKYEREYDFNKAAEVKYGEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVE
GEREKLLKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKTLARNLFDSDDNIIRID
MSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVILFDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTL
IIMTSNIGSNYLLEAGGNITETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDITIE
VTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKDENIEVLVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-89 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003218420.1 chaperone VFG2076 Protein 8e-86 41