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Name : CDR20291_1793 (CDR20291_1793) Accession : YP_003218283.1 Strain : Clostridium difficile R20291 Genome accession: NC_013316 Putative virulence/resistance : Unknown Product : DNA topoisomerase Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : - Position : 2095706 - 2097412 bp Length : 1707 bp Strand : + Note : - DNA sequence : ATGAAGTTAGTTATTGCAGAAAAGCCGAGTGTTGCAATCTCCATTGCAAAGGTTATTGGAGCAAATAAAAAGAAAGACGG ATATTATGAAGGAAACGGATATAGGGTGAGCTGGTGCGTTGGACACCTAATTCAAATGGCAAATCCGGATGCTTATGATG AAAAGTACGCCAAGTGGAATATGGCTGATTTACCGATTATTCCGAGCGACTACAAGTATGAAGTAGCAAAGGCAACCAAG AAGCAGTTTAACATCCTTAAAAAGCTGATGAATGATAAGGAGGTTGATACGGTTATCAATGCGTGCGATGCAGGGCGTGA GGGAGAAAGTATTTTTAGACTTGTATATAATCAAGTGAATTGTAAAAAGAAGATGAAACGCCTTTGGATTTCTTCAATGG AAGATAGTGCCATTAAAGAGGGTTTTGATAACCTAACAGACGGAAAAGACTATGATAATCTCTTTGAATCGGCACAGGCA AGAGCTATTGCGGATTGGTTAGTCGGAATGAATATTAGTAGGCTCTACTCTTGTCTGTATCAGCAAAATTACAGTGTTGG CAGAGTGCAGACACCTACCCTTGCCATGATTGTAAAAAGAGATGATGAGATAGCAAATTATCAGAAAGAAAAATATTACA CAGTAGAGCTTTCTATGAATGGATTTACACTCTCCACAGACAGAATTGATGATGAAGTTGCTGCTGAACAGCTTATAAGT TTAGTAGGCGATAAGATTGAAATTACTGATGTTATTCAAAAAGAAAAAATTACAAAGCCTGATTTACCTTTTGACCTAAC TACGCTTCAAAGGGAGTGCAATAAATATTTTGGATATAGTGCCAAGCAGACACTTGACTATACTCAAAGCCTGTATGAAA AGAAACTGATTACTTACCCCAGAACAGACAGCAGATGTTTAACAGAGGATATGATTGTGAGTACAGTCAACAACATTTTG GGTAAAAATGACTTTGATACAGAGCGTATCAAGGTAGTATTTAACTCTAAAAAGGTTACGGACCATCATGCAATCATACC GACAATCAGTTCAGTAAAAGAAGATGTTTCTGAATTACCTTTAAGTGAAGCAAAAGTTTACTTCCTTATATCCGATAAAT TTCATGCAAGTGTAGGCTATCCGCTTATTGAAAATACAACAAAGATTGTAGCTTCATTTGACGGTTTTGAATTTACAAGT TCAGGTAAGGTAATTAAGGATGAAGGCTTTAGCAAATACCTTAAAGAATACAAATCAAAAAAGAGTGAAGATGCTGTATT GCCCGATGTAAGTGTTGGTGATGTTTTGAGCGTTGAAAATAAAGAGGTTAAAGAAAAATTTACCCAACCTCCGAAACACT TTACTGAAGATACGCTCTTAAAGTCTATGGAGATTGCGGGAAATGATGCCTTAGAAAAAGGTGTAGAGGTGGAAAGAAAA GGTCTTGGCACTCCGGCAACAAGGGCAGGAATTATTGAAAATCTAATCTTTAAGAGATTTGTCGAAAGAGATAAGAAGAA TCTAATTGCAACGCATAAAGGAATCAGCCTTGTAACGATTGTAGCAGATACCTTTAAGTCGGCAGAAACGACAGCAAAGT GGGAAATGGAATTATCTGATATTGCTCAGGGTAAATCCTCTAAGAAAGAATTTTTAGATGCGATTGAAAATGAGATAAAA GAAGCGGTTTTGACATATCGCAAGTAA Protein sequence : MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLIQMANPDAYDEKYAKWNMADLPIIPSDYKYEVAKATK KQFNILKKLMNDKEVDTVINACDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDNLTDGKDYDNLFESAQA RAIADWLVGMNISRLYSCLYQQNYSVGRVQTPTLAMIVKRDDEIANYQKEKYYTVELSMNGFTLSTDRIDDEVAAEQLIS LVGDKIEITDVIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYTQSLYEKKLITYPRTDSRCLTEDMIVSTVNNIL GKNDFDTERIKVVFNSKKVTDHHAIIPTISSVKEDVSELPLSEAKVYFLISDKFHASVGYPLIENTTKIVASFDGFEFTS SGKVIKDEGFSKYLKEYKSKKSEDAVLPDVSVGDVLSVENKEVKEKFTQPPKHFTEDTLLKSMEIAGNDALEKGVEVERK GLGTPATRAGIIENLIFKRFVERDKKNLIATHKGISLVTIVADTFKSAETTAKWEMELSDIAQGKSSKKEFLDAIENEIK EAVLTYRK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| EFAU085_00720 | YP_008394244.1 | DNA topoisomerase III | Not tested | Not named | Protein | 5e-118 | 47 |
| topB-2 | NP_815968.1 | DNA topoisomerase III | Not tested | Not named | Protein | 2e-128 | 47 |
