Gene Information

Name : thiC (CDR20291_1600)
Accession : YP_003218095.1
Strain : Clostridium difficile R20291
Genome accession: NC_013316
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1886279 - 1887694 bp
Length : 1416 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTTAGGAGAAATTTGTCTAAGTGTATATACGATTATAAGAGTGCTTTCCAAACGAGGAAAAGCACTTTTTTTATTTTC
AAAAACTATAACTTTAATCTTGGAGGATTGTAATATGAACTATACAACACAAATGGATGCTGCTAGAAAAGGCATAATAA
CTAAAGAAATGGAAATCGTTTCTCAAAAAGAACAGGTAGATGTAAATGAATTAAGAGAATTAATAGCAAATGGACAAGTT
GTTATACCAGCTAATAAAAATCATAAATCTTTAAGTGCAGAAGGTGTAGGTAAAAATTTAAGAACAAAAATAAATGTAAA
TCTAGGAATTTCAAGAGATTGTAAGGATATAGAAAAAGAACTTGAAAAAGTTAGAGTAGCAATAGACATGAAAGCTGAAG
CTATAATGGATTTAAGTAATTATGGCAAAACTAGAGAATTTAGAGAAAAGGTTGTTGAAATGTCACCTGCAATGATAGGT
TCAGTACCTATGTATGATGCAGTAGGATATTTGGAAAAAGAATTAAAAGATATAACAGAAGAAGAGTTTTTAAATGTAAT
AAGACAACATGCTATTGATGGAGTAGACTTTATTACTATACATGCAGGTCTTACAAGAAGTGTTTGCCAAAAAATAAAAA
ATCATGAGAGATTGACTCATATAGTATCTCGTGGAGGTTCTTTATTGTTTGCATGGATGGAATTAAATAATAAGGAAAAT
CCTATTTATACTAATTTTGATAAAATATTGGATATATGTGAAGAATATGATGTTACATTGAGTTTAGGAGATGCTTGTAG
ACCAGGTTGTATAAAAGATTCTACTGATGGTGTTCAAATTCAAGAACTTGTAGTATTAGGTGAACTTACTAAAAGAGCAT
GGGAAAGAAATGTACAAGTAATGATAGAAGGTCCTGGACACATGGCTATTGATGAAATAGAAGCAAATGTAGTATTAGAA
AAGAGATTATGCCATGGAGCACCTTTTTATGTTCTTGGACCATTGGTTACAGATATAGCACCAGGTTATGACCATATAAC
AAGTGCAATAGGAGGAGCTTTAGCATGTGCTAAAGGAGTAGATTTTTTATGTTATGTAACTCCAGCAGAACATTTAAGAT
TGCCTAATTTAGATGATATGAAAGAGGGTATAATAGCTGCAAAGATAGCTGCTCATGCAGGAGATATAGCTAAAAATGTT
AAAGGTGCTCGTGAATGGGATAATAAGATGAGTAAAGCTAGAGCTGATTTAGACTGGTGTGAGATGTTTAGACTTGCAAT
AGACCCTGAAAAAGCTAAGAGATACAGAGATGAATCAACTCCTACTCATGAGGATAGTTGTACTATGTGTGGAAAAATGT
GCTCAATGAGAACAGTTAAGAAAATATTAAACAATGAGGAACTTAATCTAATATAA

Protein sequence :
MLGEICLSVYTIIRVLSKRGKALFLFSKTITLILEDCNMNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQV
VIPANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSNYGKTREFREKVVEMSPAMIG
SVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFITIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKEN
PIYTNFDKILDICEEYDVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIEANVVLE
KRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHLRLPNLDDMKEGIIAAKIAAHAGDIAKNV
KGAREWDNKMSKARADLDWCEMFRLAIDPEKAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-69 46
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-69 46